Pyruvate, phosphate dikinase (original) (raw)
Die Pyruvat-Phosphat-Dikinase (PPDK) (EC 2.7.9.1) gehört zur Enzymklasse der Phoshphotransferasen und katalysiert die ATP-abhängige Phosphorylierung von Pyruvat zu Phosphoenolpyruvat. Erstmals beschrieben wurde die PPDK in Gräsern und der parasitär lebenden Amöbe Entamoeba histolytica. Einige hauptsächlich anaerob lebende Bakterien und Protozoen nutzen diese Reaktion in umgekehrter, Pyruvat formender Richtung zur Gewinnung von ATP.
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| dbo:abstract | Die Pyruvat-Phosphat-Dikinase (PPDK) (EC 2.7.9.1) gehört zur Enzymklasse der Phoshphotransferasen und katalysiert die ATP-abhängige Phosphorylierung von Pyruvat zu Phosphoenolpyruvat. Erstmals beschrieben wurde die PPDK in Gräsern und der parasitär lebenden Amöbe Entamoeba histolytica. Einige hauptsächlich anaerob lebende Bakterien und Protozoen nutzen diese Reaktion in umgekehrter, Pyruvat formender Richtung zur Gewinnung von ATP. (de) La piruvato, fosfato dicinasa (PPDK) (número EC 2.7.9.1) es una enzima que cataliza la reacción: Piruvato + fosfato + ATP Fosfoenolpiruvato + difosfato + AMP Esta enzima se ha estudiado principalmente en las plantas, pero también se ha estudiado en algunas bacterias. Es una enzima clave en la gluconeogénesis y en la fotosíntesis, y es responsable de la reacción inversa que cataliza la piruvato cinasa en la glucólisis. Se ha demostrado que la piruvato, fosfato dicinasa sufre regulación día/noche por la proteína reguladora de la piruvato dicinasa (PDRP) que fosforila reversiblemente la Thr-456. (es) Pyruvate, phosphate dikinase, or PPDK (EC 2.7.9.1) is an enzyme in the family of transferases that catalyzes the chemical reaction ATP + pyruvate + phosphate AMP + phosphoenolpyruvate + diphosphate This enzyme has been studied primarily in plants, but it has been studied in some bacteria as well. It is a key enzyme in gluconeogenesis and photosynthesis that is responsible for reversing the reaction performed by pyruvate kinase in Embden-Meyerhof-Parnas glycolysis. It should not be confused with pyruvate, water dikinase. It belongs to the family of transferases, to be specific, those transferring phosphorus-containing groups (phosphotransferases) with paired acceptors (dikinases). This enzyme participates in pyruvate metabolism and carbon fixation. (en) La pyruvate, phosphate dikinase est une phosphotransférase qui catalyse la réaction : ATP + pyruvate + Pi AMP + phosphoénolpyruvate + PPi. Cette enzyme a été étudiée essentiellement chez les plantes, ainsi que chez certaines bactéries. Le phosphoénolpyruvate formé est un substrat de la phosphoénolpyruvate carboxylase qui permet la fixation du dioxyde de carbone CO2 sous forme d'ion bicarbonate HCO3− dans le cadre de la fixation du carbone en C4. (fr) |
| dbo:ecNumber | 2.7.9.1 |
| dbo:thumbnail | wiki-commons:Special:FilePath/1kc7.jpg?width=300 |
| dbo:wikiPageID | 14680754 (xsd:integer) |
| dbo:wikiPageLength | 17234 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1044464252 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Carbon_dioxide dbr:Carbon_fixation dbr:Amebicide dbr:Pyruvate_kinase dbr:Entamoeba_histolytica dbr:List_of_enzymes dbr:Messenger_RNA dbr:Nucleotide dbr:Base_(chemistry) dbr:Hybrid_(biology) dbr:D-alanine—D-alanine_ligase dbr:Intron dbr:Limiting_factor dbr:KDa dbr:(Pyruvate,_phosphate_dikinase)-phosphate_phosphotransferase dbc:Enzymes_of_known_structure dbr:Chemical_reaction dbr:Pyrophosphatase dbr:Pyruvate,_water_dikinase dbr:Enzyme dbr:Glutamic_acid dbr:Glycolysis dbr:Angstrom dbr:Maize dbr:Clostridium dbr:Point_mutation dbr:Protein_Data_Bank dbr:Protein_subunit dbr:Stroma_(fluid) dbr:Swivel dbr:C4_carbon_fixation dbr:Adenylate_kinase dbr:Threonine dbr:Crystal_structures dbr:Adenosine_monophosphate dbr:Adenosine_triphosphate dbr:Amino_acid dbr:Amino_acids dbr:Cysteine dbc:EC_2.7.9 dbr:Evolution dbr:PH dbr:Dikinase dbr:Protein dbr:Regulation dbr:Rice dbr:Histidine dbr:CDNA dbr:Arginine dbr:Asparagine dbr:Binding_site dbr:Homotetramer dbr:Terminator_(genetics) dbr:Tertiary_structure dbr:Translation_(geometry) dbr:C-terminus dbr:Photosynthesis dbr:Exergonic dbr:Catalysis dbr:Reaction_mechanism dbr:Rotation dbr:Species dbr:N-terminus dbr:Phosphorylation dbr:Phosphotransferase dbr:Inorganic_phosphate dbr:Mesophyll_tissue dbr:Transferase dbr:Enzyme_substrate dbr:Phosphoenolpyruvate dbr:Diphosphate dbr:Pyruvate dbr:Pyruvate_metabolism dbr:Bundle_sheath dbr:Irreversible_reaction dbr:Oxaloacetate dbr:File:PPDK_Regulatory_Protein.jpg dbr:File:PPDK_reaction.svg |
| dbp:below | CATH domains 1vbgA01-1vbgA04 (en) See domains below. (en) |
| dbp:caption | Pyruvate phosphate dikinase dimer, Clostridium symbiosum (en) |
| dbp:casNumber | 9027 (xsd:integer) |
| dbp:cath | 1 (xsd:integer) |
| dbp:ecNumber | 2.700000 (xsd:double) |
| dbp:goCode | 50242 (xsd:integer) |
| dbp:interpro | IPR000121 (en) IPR002192 (en) IPR008279 (en) IPR010121 (en) |
| dbp:iubmbEcNumber | 2 (xsd:integer) |
| dbp:name | Pyruvate, phosphate dikinase (en) PEP-utilizing enzyme, C-terminal PEP-binding (en) PEP-utilizing enzyme, Central motile domain (en) Pyruvate phosphate dikinase, N-teminal ATP-grasp (en) pyruvate, phosphate dikinase (en) |
| dbp:pfam | PF00391 (en) PF01326 (en) PF02896 (en) |
| dbp:prosite | PS00370 (en) PS00742 (en) |
| dbp:scop | d1vbga1 (en) d1vbga2 (en) d1vbga3 (en) |
| dbp:symbol | PPDK (en) PEP-utilizers (en) PEP-utilizers_C (en) PPDK_N (en) |
| dbp:wikiPageUsesTemplate | dbt:UniProt dbt:Cite_journal dbt:EC_number dbt:Enzyme dbt:Enzymes dbt:Kinases dbt:PDB_link dbt:Portal_bar dbt:Refbegin dbt:Refend dbt:Reflist dbt:PDB dbt:Pfam_box |
| dcterms:subject | dbc:Enzymes_of_known_structure dbc:EC_2.7.9 |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfKnownStructure |
| rdfs:comment | Die Pyruvat-Phosphat-Dikinase (PPDK) (EC 2.7.9.1) gehört zur Enzymklasse der Phoshphotransferasen und katalysiert die ATP-abhängige Phosphorylierung von Pyruvat zu Phosphoenolpyruvat. Erstmals beschrieben wurde die PPDK in Gräsern und der parasitär lebenden Amöbe Entamoeba histolytica. Einige hauptsächlich anaerob lebende Bakterien und Protozoen nutzen diese Reaktion in umgekehrter, Pyruvat formender Richtung zur Gewinnung von ATP. (de) La piruvato, fosfato dicinasa (PPDK) (número EC 2.7.9.1) es una enzima que cataliza la reacción: Piruvato + fosfato + ATP Fosfoenolpiruvato + difosfato + AMP Esta enzima se ha estudiado principalmente en las plantas, pero también se ha estudiado en algunas bacterias. Es una enzima clave en la gluconeogénesis y en la fotosíntesis, y es responsable de la reacción inversa que cataliza la piruvato cinasa en la glucólisis. Se ha demostrado que la piruvato, fosfato dicinasa sufre regulación día/noche por la proteína reguladora de la piruvato dicinasa (PDRP) que fosforila reversiblemente la Thr-456. (es) La pyruvate, phosphate dikinase est une phosphotransférase qui catalyse la réaction : ATP + pyruvate + Pi AMP + phosphoénolpyruvate + PPi. Cette enzyme a été étudiée essentiellement chez les plantes, ainsi que chez certaines bactéries. Le phosphoénolpyruvate formé est un substrat de la phosphoénolpyruvate carboxylase qui permet la fixation du dioxyde de carbone CO2 sous forme d'ion bicarbonate HCO3− dans le cadre de la fixation du carbone en C4. (fr) Pyruvate, phosphate dikinase, or PPDK (EC 2.7.9.1) is an enzyme in the family of transferases that catalyzes the chemical reaction ATP + pyruvate + phosphate AMP + phosphoenolpyruvate + diphosphate This enzyme has been studied primarily in plants, but it has been studied in some bacteria as well. It is a key enzyme in gluconeogenesis and photosynthesis that is responsible for reversing the reaction performed by pyruvate kinase in Embden-Meyerhof-Parnas glycolysis. It should not be confused with pyruvate, water dikinase. (en) |
| rdfs:label | Pyruvat-Phosphat-Dikinase (de) Piruvato, fosfato dicinasa (es) Pyruvate phosphate dikinase (fr) Pyruvate, phosphate dikinase (en) |
| owl:sameAs | freebase:Pyruvate, phosphate dikinase http://www4.wiwiss.fu-berlin.de/drugbank/resource/targets/3450 wikidata:Pyruvate, phosphate dikinase dbpedia-de:Pyruvate, phosphate dikinase dbpedia-es:Pyruvate, phosphate dikinase dbpedia-fr:Pyruvate, phosphate dikinase dbpedia-sh:Pyruvate, phosphate dikinase dbpedia-sr:Pyruvate, phosphate dikinase https://global.dbpedia.org/id/2L9BD yago-res:Pyruvate, phosphate dikinase |
| prov:wasDerivedFrom | wikipedia-en:Pyruvate,_phosphate_dikinase?oldid=1044464252&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/1kc7.jpg wiki-commons:Special:FilePath/PPDK_Regulatory_Protein.jpg wiki-commons:Special:FilePath/PPDK_reaction.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Pyruvate,_phosphate_dikinase |
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