Direct interaction of two polarity complexes implicated in epithelial tight junction assembly (original) (raw)
References
Bhat, M.A. et al. Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity. Cell96, 833–845 (1999). ArticleCAS Google Scholar
Hong, Y., Stronach, B., Perrimon, N., Jan, L.Y. & Jan, Y.N. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature414, 634–638 (2001). ArticleCAS Google Scholar
Bachmann, A., Schneider, M., Thellenberg, E., Grawe, F. & Knust, E. Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity. Nature414, 638–643 (2001). ArticleCAS Google Scholar
Roh, M.H. et al. The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost. J. Cell Biol.157, 161–172 (2002). ArticleCAS Google Scholar
Wodarz, A., Ramrath, A., Grimm, A. & Knust, E. Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts. J. Cell Biol.150, 1361–1374 (2000). ArticleCAS Google Scholar
Petronczki, M. & Knoblich, J.A. DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila. Nature Cell Biol.3, 43–49 (2001). ArticleCAS Google Scholar
Joberty, G., Petersen, C., Gao, L. & Macara, I.G. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nature Cell Biol.2, 531–539 (2000). ArticleCAS Google Scholar
Lin, D. et al. A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nature Cell Biol.2, 540–547 (2000). ArticleCAS Google Scholar
Yeaman, C., Grindstaff, K.K. & Nelson, W.J. New perspectives on mechanisms involved in generating epithelial cell polarity. Physiol. Rev.79, 73–98 (1999). ArticleCAS Google Scholar
Hung, A.Y. & Sheng, M. PDZ domains: structural modules for protein complex assembly. J. Biol. Chem.277, 5699–5702 (2002). ArticleCAS Google Scholar
Wodarz, A. Establishing cell polarity in development. Nature Cell Biol.4, E39–E44 (2002). ArticleCAS Google Scholar
Tepass, U. & Knust, E. Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster. Dev. Biol.159, 311–326 (1993). ArticleCAS Google Scholar
Doerks, T. et al. L27, a novel heterodimerization domain in receptor targeting proteins Lin-2 and Lin-7. Trends Biochem. Sci.25, 317–318 (2000). ArticleCAS Google Scholar
Tepass, U. Adherens junctions: new insight into assembly, modulation and function. Bioessays24, 690–695 (2002). ArticleCAS Google Scholar
Gao, L., Joberty, G. & Macara, I.G. Assembly of epithelial tight junctions is negatively regulated by Par6. Curr. Biol.12, 221–225 (2002). ArticleCAS Google Scholar
Suzuki, A. et al. Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J. Cell Biol.152, 1183–1196 (2001). ArticleCAS Google Scholar
Qiu, R.G., Abo, A. & Martin, S.G. A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCζ signaling and cell transformation. Curr. Biol.10, 697–707 (2000). ArticleCAS Google Scholar
Tabuse, Y. et al. Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans. Development125, 3607–3614 (1998). CASPubMed Google Scholar
Izumi, Y. et al. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J. Cell Biol.143, 95–106 (1998). ArticleCAS Google Scholar
Makarova, O., Roh, M.H., Liu, C.J., Laurinec, S. & Margolis, B. Mammalian Crumbs3 is small transmembrane protein linked to Pals1. Gene (in the press).
Lemmers, C. et al. hINADl/PATJ, a homolog of Discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells. J. Biol. Chem.277, 25408–25415 (2002). ArticleCAS Google Scholar
Itoh, M. et al. Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions. J. Cell Biol.154, 491–497 (2001). ArticleCAS Google Scholar
Ebnet, K. et al. The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM). EMBO J.20, 3738–3748 (2001). ArticleCAS Google Scholar
Ohno, S. Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity. Curr. Opin Cell Biol.13, 641–648 (2001). ArticleCAS Google Scholar
Horne-Badovinac, S. et al. Positional cloning of heart and soul reveals multiple roles for PKC λ in zebrafish organogenesis. Curr. Biol.11, 1492–1502 (2001). ArticleCAS Google Scholar
Etienne-Manneville, S. & Hall, A. Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCζ. Cell106, 489–498 (2001). ArticleCAS Google Scholar
Gotta, M., Abraham, M.C. & Ahringer, J. CDC-42 controls early cell polarity and spindle orientation in C. elegans. Curr. Biol.11, 482–488 (2001). ArticleCAS Google Scholar
Kay, A.J. & Hunter, C.P. CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans. Curr. Biol.11, 474–481 (2001). ArticleCAS Google Scholar