Dynamic programming of CD8+ T lymphocyte responses (original) (raw)

References

  1. Harty, J.T., Tvinnereim, A.R. & White, D.W. CD8+ T cell effector mechanisms in resistance to infection. Annu. Rev. Immunol. 18, 275–308 (2000).
    Article CAS PubMed Google Scholar
  2. Kaech, S.M., Wherry, E.J. & Ahmed, R. Effector and memory T-cell differentiation: implications for vaccine development. Nat. Rev. Immunol. 2, 251–262 (2002).
    Article CAS PubMed Google Scholar
  3. Murali-Krishna, K. et al. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8, 177–187 (1998).
    Article CAS PubMed Google Scholar
  4. Butz, E.A. & Bevan, M.J. Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. Immunity 8, 167–175 (1998).
    Article CAS PubMed PubMed Central Google Scholar
  5. Blattman, J.N. et al. Estimating the precursor frequency of naive antigen-specific CD8 T cells. J. Exp. Med. 195, 657–664 (2002).
    Article CAS PubMed PubMed Central Google Scholar
  6. Lanzavecchia, A. & Sallusto, F. Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 290, 92–97 (2000).
    Article CAS PubMed Google Scholar
  7. Heath, W.R. & Carbone, F.R. Cross-presentation, dendritic cells, tolerance and immunity. Annu. Rev. Immunol. 19, 47–64 (2001).
    Article CAS PubMed Google Scholar
  8. Steinman, R.M. & Nussenzweig, M.C. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc. Natl. Acad. Sci. USA 99, 351–8 (2002).
    Article CAS PubMed PubMed Central Google Scholar
  9. Iezzi, G., Karjalainen, K. & Lanzavecchia, A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 8, 89–95 (1998).
    Article CAS PubMed Google Scholar
  10. Iezzi, G., Scotet, E., Scheidegger, D. & Lanzavecchia, A. The interplay between the duration of TCR and cytokine signaling determines T cell polarization. Eur. J. Immunol. 29, 4092–4101 (1999).
    Article CAS PubMed Google Scholar
  11. van Stipdonk, M.J., Lemmens, E.E. & Schoenberger, S.P. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat. Immunol. 2, 423–429 (2001).
    Article CAS PubMed Google Scholar
  12. Kaech, S.M. & Ahmed, R. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2, 415–422 (2001).
    Article CAS PubMed PubMed Central Google Scholar
  13. Wong, P. & Pamer, E. Antigen-independent CD8 T cell proliferation. J. Immunol. 166, 5864–5868 (2001).
    Article CAS PubMed Google Scholar
  14. Miller, M.J., Wei, S.H., Parker, I. & Cahalan, M.D. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296, 1869–1873 (2002).
    Article CAS PubMed Google Scholar
  15. Stoll, S., Delon, J., Brotz, T.M. & Germain, R.N. Dynamic imaging of T cell–dendritic cell interactions in lymph nodes. Science 296, 1873–1876 (2002).
    Article PubMed Google Scholar
  16. Schoenberger, S.P. et al. Efficient direct priming of tumor-specific cytotoxic T lymphocyte in vivo by an engineered APC. Cancer Res. 58, 3094–3100 (1998).
    CAS PubMed Google Scholar
  17. Hogquist, K.A. et al. T cell receptor antagonist peptides induce positive selection. Cell 76, 17–27 (1994).
    Article CAS PubMed Google Scholar
  18. Plas, D., Rathmell, J. & Thompson, C. Homeostatic control of lymphocyte survival: potential origins and implications. Nat. Immunol. 3, 515–521 (2002).
    Article CAS PubMed Google Scholar
  19. Chao, D. et al. Bcl-XL and Bcl-2 repress a common pathway of cell death. J Exp Med 182, 821–828 (1995).
    Article CAS PubMed Google Scholar
  20. Strasser, A., Harris, A. & Cory, S. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67, 889–899 (1991).
    Article CAS PubMed Google Scholar
  21. Dai, Z., Konieczny, B. & Lakkis, F. The dual role of IL-2 in the generation and maintenance of CD8+ memory T cells. J. Immunol. 165, 3031–3036 (2000).
    Article CAS PubMed Google Scholar
  22. Oehen, S. & Brduscha-Riem, K. Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division. J. Immunol. 161, 5338–5346 (1998).
    CAS PubMed Google Scholar
  23. Kurts, C., Kosaka, H., Carbone, F.R., Miller, J.F. & Heath, W.R. Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8+ T cells. J. Exp. Med. 186, 239–245 (1997).
    Article CAS PubMed PubMed Central Google Scholar
  24. Kurts, C. et al. CD4+ T cell help impairs CD8+ T cell deletion induced by cross- presentation of self-antigens and favors autoimmunity. J. Exp. Med. 186, 2057–2062 (1997).
    Article CAS PubMed PubMed Central Google Scholar
  25. Nelson, B. & Willerford, D. The biology of the interleukin-2 receptor. Adv. Immunol. 70, 1–81 (1998).
    Article CAS PubMed Google Scholar
  26. Liu, K. et al. Immune tolerance after delivery of dying cells to dendritic cells in situ. J. Exp. Med. 196, 1091–1097 (2002).
    Article CAS PubMed PubMed Central Google Scholar

Download references