Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1 (original) (raw)
Ferrara, N. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am. J. Physiol. Cell. Physiol.280, C1358–C1366 (2001). ArticleCASPubMed Google Scholar
Post, M.J., Laham, R., Sellke, F.W. & Simons, M. Therapeutic angiogenesis in cardiology using protein formulations. Cardiovasc Res.49, 522–531 (2001). ArticleCASPubMed Google Scholar
Carmeliet, P. & Jain, R.K. Angiogenesis in cancer and other diseases. Nature407, 249–257 (2000). ArticleCASPubMed Google Scholar
Veikkola, T., Karkkainen, M., Claesson-Welsh, L. & Alitalo, K. Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res.60, 203–212 (2000). CASPubMed Google Scholar
Hiratsuka, S., Minowa, O., Kuno, J., Noda, T. & Shibuya, M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl. Acad. Sci. USA95, 9349–9354 (1998). ArticleCASPubMedPubMed Central Google Scholar
Shibuya, M. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct. Funct.26, 25–35 (2001). ArticleCASPubMed Google Scholar
Persico, M.G., Vincenti, V. & DiPalma, T. Structure, expression and receptor-binding properties of placenta growth factor (PlGF). Curr. Top. Microbiol. Immunol.237, 31–40 (1999). CASPubMed Google Scholar
Fong, G.H., Rossant, J., Gertsenstein, M. & Breitman, M.L. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature376, 66–70 (1995). ArticleCASPubMed Google Scholar
Park, J.E., Chen, H.H., Winer, J., Houck, K.A. & Ferrara, N. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J. Biol. Chem.269, 25646–25654 (1994). CASPubMed Google Scholar
Carmeliet, P. et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nature Med.7, 575–583 (2001). ArticleCASPubMed Google Scholar
Hiratsuka, S. et al. Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. Cancer Res.61, 1207–1213 (2001). CASPubMed Google Scholar
Weng, D.E. & Usman, N. Angiozyme: a novel angiogenesis inhibitor. Curr. Oncol. Rep.3, 141–146 (2001). ArticleCASPubMed Google Scholar
Ishida, A. et al. Expression of vascular endothelial growth factor receptors in smooth muscle cells. J. Cell. Physiol.188, 359–368 (2001). ArticleCASPubMed Google Scholar
van Royen, N. et al. Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive disease. Cardiovasc. Res.49, 543–553 (2001). ArticleCASPubMed Google Scholar
Hoefer, I.E., van Royen, N., Buschmann, I.R., Piek, J.J. & Schaper, W. Time course of arteriogenesis following femoral artery occlusion in the rabbit. Cardiovasc. Res.49, 609–617 (2001). ArticleCASPubMed Google Scholar
Pettersson, A. et al. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab. Invest.80, 99–115 (2000). ArticleCASPubMed Google Scholar
Dvorak, H.F., Dvorak, A.M., Manseau, E.J., Wiberg, L. & Churchill, W.H. Fibrin gel investment associated with line 1 and line 10 solid tumor growth, angiogenesis, and fibroplasia in guinea pigs Role of cellular immunity, myofibroblasts, microvascular damage, and infarction in line 1 tumor regression. J. Natl. Cancer Inst.62, 1459–1472 (1979). CASPubMed Google Scholar
McLeod, D.S. et al. Localization of VEGF receptor-2 (KDR/Flk-1) and effects of blocking it in oxygen-induced retinopathy. Invest. Ophthalmol. Vis. Sci.43, 474–482 (2002). PubMed Google Scholar
Celletti, F.L. et al. Vascular endothelial growth factor enhances atherosclerotic plaque progression. Nature Med.7, 425–429 (2001). ArticleCASPubMed Google Scholar
Moulton, K.S. Plaque angiogenesis and atherosclerosis. Curr. Atheroscler. Rep.3, 225–233 (2001). ArticleCASPubMed Google Scholar
Weber, A.J. & De Bandt, M. Angiogenesis: general mechanisms and implications for rheumatoid arthritis. Joint Bone Spine67, 366–383 (2000). CASPubMed Google Scholar
Miotla, J., Maciewicz, R., Kendrew, J., Feldmann, M. & Paleolog, E. Treatment with soluble VEGF receptor reduces disease severity in murine collagen-induced arthritis. Lab. Invest.80, 1195–1205 (2000). ArticleCASPubMed Google Scholar
Sone, H. et al. Neutralization of vascular endothelial growth factor prevents collagen-induced arthritis and ameliorates established disease in mice. Biochem. Biophys. Res. Commun.281, 562–568 (2001). ArticleCASPubMed Google Scholar
Courtenay, J.S., Dallman, M.J., Dayan, A.D., Martin, A. & Mosedale, B. Immunisation against heterologous type II collagen induces arthritis in mice. Nature283, 666–668 (1980). ArticleCASPubMed Google Scholar
Bottomley, M.J. et al. Placenta growth factor (PlGF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is co-expressed with VEGF in synovial fluid. Clin. Exp. Immunol.119, 182–188 (2000). ArticleCASPubMedPubMed Central Google Scholar
Lyden, D. et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nature Med.7, 1194–1201 (2001). ArticleCASPubMed Google Scholar
Riessen, R., Kearney, M., Lawler, J. & Isner, J.M. Immunolocalization of thrombospondin-1 in human atherosclerotic and restenotic arteries. Am. Heart J.135, 357–364 (1998). ArticleCASPubMed Google Scholar
Carmeliet, P. VEGF gene therapy: stimulating angiogenesis or angioma-genesis?. Nature Med.6, 1102–1103 (2000). ArticleCASPubMed Google Scholar
Lazarous, D.F. et al. Basic fibroblast growth factor in patients with intermittent claudication: results of a phase I trial. J. Am. Coll. Cardiol.36, 1239–1244 (2000). ArticleCASPubMed Google Scholar
Hattori, K. et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment. Nature Med.8, advance online publication, 1 July 2002 (doi:10.1038/nm740).
Sawano, A. et al. Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. Blood97, 785–791 (2001). ArticleCASPubMed Google Scholar
Clauss, M. Functions of the VEGF receptor-1 (FLT-1) in the vasculature. Trends Cardiovasc. Med.8, 241–245 (1998). ArticleCASPubMed Google Scholar
Brenchley, P.E. Angiogenesis in inflammatory joint disease: a target for therapeutic intervention. Clin. Exp. Immunol.121, 426–429 (2000). ArticleCASPubMedPubMed Central Google Scholar
Libby, P. What have we learned about the biology of atherosclerosis? The role of inflammation. Am. J. Cardiol.88, 3J–6J (2001). CASPubMed Google Scholar
Lutgens, E. et al. Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype. Proc. Natl. Acad. Sci. USA97, 7464–7469 (2000). ArticleCASPubMedPubMed Central Google Scholar
Simons, M. et al. Clinical trials in coronary angiogenesis: issues, problems, consensus: an expert panel summary. Circulation102, E73–E86 (2000). ArticleCASPubMed Google Scholar
Witte, L. et al. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy. Cancer Metastasis Rev.17, 155–161 (1998). ArticleCASPubMed Google Scholar
Luttun, A. et al. Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein-deficient mice. Arterioscler. Thromb. Vasc. Biol.22, 499–505 (2002). ArticleCASPubMed Google Scholar
Matthys, P. et al. Enhanced autoimmune arthritis in IFN-γ receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells. J. Immunol.163, 3503–3510 (1999). CASPubMed Google Scholar
Matthys, P. et al. Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-γ receptor-deficient mice. Eur. J. Immunol.28, 2143–2151 (1998). ArticleCASPubMed Google Scholar
Priller, J. et al. Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment. Nature Med.7, 1356–1361 (2001). ArticleCASPubMed Google Scholar
Matsumoto, K., Ishihara, K., Tanaka, K., Inoue, K. & Fushiki, T. An adjustable-current swimming pool for the evaluation of endurance capacity of mice. J. Appl. Physiol.81, 1843–1849 (1996). ArticleCASPubMed Google Scholar
Carmeliet, P. et al. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nature Med.5, 495–502 (1999). ArticleCASPubMed Google Scholar