HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages (original) (raw)
Stahl-Hennig, C. et al. Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus. Science285, 1261–1265 (1999). ArticleCAS Google Scholar
Zhang, Z. et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science286, 1353–1357 (1999). ArticleCAS Google Scholar
Granelli-Piperno, A., Delgado, E., Finkel, V., Paxton, W. & Steinman, R.M. Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells. J. Virol.72, 2733–2737 (1998). CASPubMedPubMed Central Google Scholar
Hu, J., Gardner, M.B. & Miller, C.J. Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells. J. Virol.74, 6087–6095 (2000). ArticleCAS Google Scholar
Rescigno, M. et al. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol.2, 361–367 (2001). ArticleCAS Google Scholar
Geijtenbeek, T.B. et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell100, 587–597 (2000). ArticleCAS Google Scholar
Banchereau, J. et al. Immunobiology of dendritic cells. Annu. Rev. Immunol.18, 767–811 (2000). ArticleCAS Google Scholar
Mellman, I. & Steinman, R.M. Dendritic cells: specialized and regulated antigen processing machines. Cell106, 255–258 (2001). ArticleCAS Google Scholar
Huang, Q. et al. The plasticity of dendritic cell responses to pathogens and their components. Science294, 870–875 (2001). ArticleCAS Google Scholar
Tortorella, D., Gewurz, B.E., Furman, M.H., Schust, D.J. & Ploegh, H.L. Viral subversion of the immune system. Annu. Rev. Immunol.18, 861–926 (2000). ArticleCAS Google Scholar
Engelmayer, J. et al. Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. J. Immunol.163, 6762–6768 (1999). CAS Google Scholar
Grosjean, I. et al. Measles virus infects human dendritic cells and blocks their allostimulatory properties for CD4+ T cells. J. Exp. Med.186, 801–812 (1997). ArticleCAS Google Scholar
de Noronha, C.M. et al. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science294, 1105–1108 (2001). ArticleCAS Google Scholar
Viscidi, R.P., Mayur, K., Lederman, H.M. & Frankel, A.D. Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1. Science246, 1606–1608 (1989). ArticleCAS Google Scholar
New, D.R., Ma, M., Epstein, L.G., Nath, A. & Gelbard, H.A. Human immunodeficiency virus type 1 Tat protein induces death by apoptosis in primary human neuron cultures. J. Neurovirol.3, 168–173 (1997). ArticleCAS Google Scholar
Swingler, S. et al. HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nature Med.5, 997–1103 (1999). ArticleCAS Google Scholar
Simmons, A., Aluvihare, V. & McMichael, A. Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity14, 763–777 (2001). ArticleCAS Google Scholar
Messner, D. et al. Endogenously expressed nef uncouples cytokine and chemokine prouction from membrane phenotypic maturation in dendritic cells. J. Immunol.169, 4172–4182 (2002). Article Google Scholar
Wu, Y. & Marsh, J.W. Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA. Science293, 1503–1506 (2001). ArticleCAS Google Scholar
Jones, K.A. Taking a new TAK on tat transactivation. Genes Dev.11, 2593–2599 (1997). ArticleCAS Google Scholar
Demarchi, F., Gutierrez, M.I. & Giacca, M. Human immunodeficiency virus type 1 tat protein activates transcription factor NF-κB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR. J. Virol.73, 7080–7086 (1999). CASPubMedPubMed Central Google Scholar
Marzio, G. & Giacca, M. Chromatin control of HIV-1 gene expression. Genetica106, 125–130 (1999). ArticleCAS Google Scholar
Chartier, C. et al. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J. Virol.70, 4805–4810 (1996). CASPubMedPubMed Central Google Scholar
Zhang, L. & Pagano, J.S. Review: structure and function of IRF-7. J. Interferon Cytokine Res.22, 95–101 (2002). Article Google Scholar
Ramana, C.V., Gil, M.P., Schreiber, R.D. & Stark, G.R. Stat1-dependent and -independent pathways in IFN-γ-dependent signaling. Trends Immunol.23, 96–101 (2002). ArticleCAS Google Scholar
Bazan, J.F. et al. A new class of membrane-bound chemokine with a CX3C motif. Nature385, 640–644 (1997). ArticleCAS Google Scholar
Luster, A.D., Unkeless, J.C. & Ravetch, J.V. γ-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature315, 672–676 (1985). ArticleCAS Google Scholar
Piali, L. et al. The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig. Eur. J. Immunol.28, 961–972 (1998). ArticleCAS Google Scholar
Van Damme, J., Proost, P., Lenaerts, J.P. & Opdenakker, G. Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family. J. Exp. Med.176, 59–65 (1992). ArticleCAS Google Scholar
Wu, L. et al. Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. Proc. Natl. Acad. Sci. USA99, 1568–1573 (2002). ArticleCAS Google Scholar
Smith, S.G., Patel, P.M., Selby, P.J. & Jackson, A.M. The response of human dendritic cells to recombinant adenovirus, recombinant Mycobacterium bovis Bacillus Calmette Guerin and biolistic methods of antigen delivery: different induction of contact-dependant and soluble signals. Immunol. Lett.76, 79–88 (2001). ArticleCAS Google Scholar
Douek, D.C. et al. HIV preferentially infects HIV-specific CD4+ T cells. Nature417, 95–98 (2002). ArticleCAS Google Scholar
Agostini, C. et al. CXC chemokines IP-10 and mig expression and direct migration of pulmonary CD8+/CXCR3+ T cells in the lungs of patients with HIV infection and T-cell alveolitis. Am. J. Respir. Crit. Care Med.162, 1466–1473 (2000). ArticleCAS Google Scholar
Frankel, A.D. & Pabo, C.O. Cellular uptake of the tat protein from human immunodeficiency virus. Cell55, 1189–1193 (1988). ArticleCAS Google Scholar
Sen, G.C. Novel functions of interferon-induced proteins. Semin. Cancer Biol.10, 93–101 (2000). ArticleCAS Google Scholar
Chang, Y.E. & Laimins, L.A. Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31. J. Virol.74, 4174–4182 (2000). ArticleCAS Google Scholar
Fujii, N., Yokosawa, N. & Shirakawa, S. Suppression of interferon response gene expression in cells persistently infected with mumps virus, and restoration from its suppression by treatment with ribavirin. Virus Res.65, 175–185 (1999). ArticleCAS Google Scholar
Weihua, X. et al. The polyoma virus T antigen interferes with interferon-inducible gene expression. Proc. Natl. Acad. Sci. USA95, 1085–1090 (1998). ArticleCAS Google Scholar
Miura, Y. et al. Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice. J. Exp. Med.193, 651–660 (2001). ArticleCAS Google Scholar
Katsikis, P.D. et al. Interleukin-1 beta converting enzyme-like protease involvement in Fas-induced and activation-induced peripheral blood T cell apoptosis in HIV infection. TNF-related apoptosis-inducing ligand can mediate activation-induced T cell death in HIV infection. J. Exp. Med.186, 1365–1372 (1997). ArticleCAS Google Scholar
Fanales-Belasio, E. et al. Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. J. Immunol.168, 197–206 (2002). ArticleCAS Google Scholar
Bender, A., Sapp, M., Schuler, G., Steinman, R.M. & Bhardwaj, N. Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. J. Immunol. Methods196, 121–135 (1996). ArticleCAS Google Scholar
Liu, Y.J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell106, 259–262 (2001). ArticleCAS Google Scholar
Waldrop, S.L., Pitcher, C.J., Peterson, D.M., Maino, V.C. & Picker, L.J. Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency. J. Clin. Invest.99, 1739–1750 (1997). ArticleCAS Google Scholar
Poon, D.T., Wu, J. & Aldovini, A. Charged amino acid residues of human immunodeficiency virus type 1 nucleocapsid p7 protein involved in RNA packaging and infectivity. J. Virol.70, 6607–6616 (1996). CASPubMedPubMed Central Google Scholar