Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4+ very small embryonic-like stem cells (original) (raw)

• Evans MJ, Kaufman MH . Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292: 154–156.
  Article CAS Google Scholar
• Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 2007; 448: 196–199.
  Article CAS Google Scholar
• Matsui Y, Zsebo K, Hogan BLM . Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell 1992; 70: 841–847.
  Article CAS Google Scholar
• Takahashi K, Yamanaka S . Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663–676.
  Article CAS Google Scholar
• Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007; 448: 318–324.
  Article CAS Google Scholar
• Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41–49.
  Article CAS Google Scholar
• D'Ippolito G, Diabira S, Howard GA, Menei P, Roos BA, Schiller PC . Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential. J Cell Sci 2004; 117: 2971–2981.
  Article CAS Google Scholar
• Liedtke S, Enczmann Jg, Waclawczyk S, Wernet P, Kogler G . Oct4 and its pseudogenes confuse stem cell research. Cell Stem Cell 2007; 1: 364–366.
  Article CAS Google Scholar
• Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, Gokhale S et al. Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell 2007; 1: 403–415.
  Article CAS Google Scholar
• Kucia M, Reca R, Campbell FR, Zuba-Surma E, Majka M, Ratajczak J et al. A population of very small embryonic-like (VSEL) CXCR4+SSEA-1+Oct-4+ stem cells identified in adult bone marrow. Leukemia 2006; 20: 857–869.
  Article CAS Google Scholar
• Kucia M, Halasa M, Wysoczynski M, Baskiewicz-Masiuk M, Moldenhawer S, Zuba-Surma E et al. Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood - preliminary report. Leukemia 2006; 21: 297–303.
  Article Google Scholar
• Kucia M, Zhang YP, Reca R, Wysoczynski M, Machalinski B, Majka M et al. Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following stroke. Leukemia 2005; 20: 18–28.
  Article Google Scholar
• Wojakowski W, Tendera M, Kucia M, Zuba-Surma E, Paczkowska E, Ciosek J et al. Mobilization of bone marrow-derived Oct-4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction. J Am Coll Cardio 2009; 53: 1–9.
  Article CAS Google Scholar
• Paczkowska E, Kucia M, Koziarska D, Halasa M, Safranow K, Masiuk M et al. Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke. Stroke 2009; 40: 1237–1244.
  Article CAS Google Scholar
• Ratajczak MZ, Machalinski B, Wojakowski W, Ratajczak J, Kucia M . A hypothesis for an embryonic origin of pluripotent Oct-4+ stem cells in adult bone marrow and other tissues. Leukemia 2007; 21: 860–867.
  Article CAS Google Scholar
• Reik W, Walter J . Genomic imprinting: parental influence on the genome. Nat Rev Genet 2001; 2: 21–32.
  Article CAS Google Scholar
• Yamazaki Y, Mann MR, Lee SS, Marh J, McCarrey JR, Yanagimachi R et al. Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning. Proc Natl Acad Sci USA 2003; 100: 12207–12212.
  Article CAS Google Scholar
• Horii T, Kimura M, Morita S, Nagao Y, Hatada I . Loss of genomic imprinting in mouse parthenogenetic embryonic stem cells. Stem Cells 2008; 26: 79–88.
  Article CAS Google Scholar
• Pannetier Ml, Feil R . Epigenetic stability of embryonic stem cells and developmental potential. Trends Biotechnol 2007; 25: 556–562.
  Article CAS Google Scholar
• Delaval K, Feil R . Epigenetic regulation of mammalian genomic imprinting. Curr Opin Genet Dev 2004; 14: 188–195.
  Article CAS Google Scholar
• Lopes S, Lewis A, Hajkova P, Dean W, Oswald J, Forne T et al. Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions. Hum Mol Genet 2003; 12: 295–305.
  Article CAS Google Scholar
• Kobayashi H, Suda C, Abe T, Kohara Y, Ikemura T, Sasaki H . Bisulfite sequencing and dinucleotide content analysis of 15 imprinted mouse differentially methylated regions (DMRs): paternally methylated DMRs contain less CpGs than maternally methylated DMRs. Cytogenet Genome Res 2006; 113: 130–137.
  Article CAS Google Scholar
• Mager J, Montgomery ND, de Villena FP-M, Magnuson T . Genome imprinting regulated by the mouse Polycomb group protein Eed. Nat Genet 2003; 33: 502–507.
  Article CAS Google Scholar
• Fournier C, Goto Y, Ballestar E, Delaval K, Hever AM, Esteller M et al. Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes. EMBO J 2002; 21: 6560–6570.
  Article CAS Google Scholar
• O'Neill LP, VerMilyea MD, Turner BM . Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nat Genet 2006; 38: 835–841.
  Article CAS Google Scholar
• Carr IM, Valleley EMA, Cordery SF, Markham AF, Bonthron DT . Sequence analysis and editing for bisulphite genomic sequencing projects. Nucl Acids Res 2007; 35: e79.
  Article Google Scholar
• Feldman N, Gerson A, Fang J, Li E, Zhang Y, Shinkai Y et al. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol 2006; 8: 188–194.
  Article CAS Google Scholar
• Margueron R, Trojer P, Reinberg D . The key to development: interpreting the histone code? Curr Opin Genet Dev 2005; 15: 163–176.
  Article CAS Google Scholar
• Kono T, Obata Y, Wu Q, Niwa K, Ono Y, Yamamoto Y et al. Birth of parthenogenetic mice that can develop to adulthood. Nature 2004; 428: 860–864.
  Article CAS Google Scholar
• Hajkova P, Erhardt S, Lane N, Haaf T, El-Maarri O, Reik W et al. Epigenetic reprogramming in mouse primordial germ cells. Mech Dev 2002; 117: 15–23.
  Article CAS Google Scholar
• Pant V, Mariano P, Kanduri C, Mattsson A, Lobanenkov V, Heuchel R et al. The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains. Genes Dev 2003; 17: 586–590.
  Article CAS Google Scholar
• Yoon B, Herman H, Hu B, Park YJ, Lindroth A, Bell A et al. Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Mol Cell Biol 2005; 25: 11184–11190.
  Article CAS Google Scholar
• Shovlin TC, Durcova-Hills G, Surani A, McLaren A . Heterogeneity in imprinted methylation patterns of pluripotent embryonic germ cells derived from pre-migratory mouse germ cells. Dev Biol 2008; 313: 674–681.
  Article CAS Google Scholar
• Zhu T-N, He H-J, Kole S, D′Souza T, Agarwal R, Morin PJ et al. Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells. J Biol Chem 2007; 282: 14816–14826.
  Article CAS Google Scholar
• Lefebvre L, Viville S, Barton SC, Ishino F, Keverne EB, Surani MA . Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest. Nat Genet 1998; 20: 163–169.
  Article CAS Google Scholar
• Chen T, Ueda Y, Dodge JE, Wang Z, Li E . Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 2003; 23: 5594–5605.
  Article CAS Google Scholar
• Bourc'his D, Xu G-L, Lin C-S, Bollman B, Bestor TH . Dnmt3 L and the establishment of maternal genomic imprints. Science 2001; 294: 2536–2539.
  Article CAS Google Scholar
• Durcova-Hills G, Tang F, Doody G, Tooze R, Surani MA . Reprogramming primordial germ cells into pluripotent stem cells. PLoS ONE 2008; 3: e3531.
  Article Google Scholar
• Eggenschwiler J, Ludwig T, Fisher P, Leighton PA, Tilghman SM, Efstratiadis A . Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. Genes Dev 1997; 11: 3128–3142.
  Article CAS Google Scholar
• Hao Y, Crenshaw T, Moulton T, Newcomb E, Tycko B . Tumour-suppressor activity of H19 RNA. Nature 1993; 365: 764–767.
  Article CAS Google Scholar
• Ludwig T, Eggenschwiler J, Fisher P, D'Ercole AJ, Davenport ML, Efstratiadis A . Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality inIgf2 and Igf1r null backgrounds. Dev Biol 1996; 177: 517–535.
  Article CAS Google Scholar
• Font de Mora J, Esteban LM, Burks DJ, Nunez A, Garces C, Garcia-Barrado MJ et al. Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis. EMBO J 2003; 22: 3039–3049.
  Article CAS Google Scholar
• Scandura JM, Boccuni P, Massague J, Nimer SD . Transforming growth factor β-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proc Natl Acad Sci USA 2004; 101: 15231–15236.
  Article CAS Google Scholar
• Umemoto T, Yamato M, Nishida K, Yang J, Tano Y, Okano T . p57Kip2 is expressed in quiescent mouse bone marrow side population cells. Biochem Biophys Res Commun 2005; 337: 14–21.
  Article CAS Google Scholar