Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells (original) (raw)
van der Oost, J., Jore, M.M., Westra, E.R., Lundgren, M. & Brouns, S.J.J. CRISPR-based adaptive and heritable immunity in prokaryotes. Trends Biochem. Sci.34, 401–407 (2009). ArticleCASPubMed Google Scholar
Deveau, H., Garneau, J.E. & Moineau, S. CRISPR/Cas system and its role in phage-bacteria interactions. Annu. Rev. Microbiol.64, 475–493 (2010). ArticleCASPubMed Google Scholar
Horvath, P. & Barrangou, R. CRISPR/Cas, the immune system of bacteria and archaea. Science327, 167–170 (2010). ArticleCASPubMed Google Scholar
Mojica, F.J.M., Díez-Villaseñor, C., García-Martínez, J. & Almendros, C. Short motif sequences determine the targets of the prokaryotic CRISPR defence system. Microbiology155, 733–740 (2009). ArticleCASPubMed Google Scholar
Gasiunas, G. & Siksnys, V. RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing? Trends Microbiol.21, 562–567 (2013). ArticleCASPubMed Google Scholar
Wang, T., Wei, J.J., Sabatini, D.M. & Lander, E.S. Genetic screens in human cells using the CRISPR-Cas9 system. Science343, 80–84 (2014). ArticleCASPubMed Google Scholar
Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science343, 84–87 (2014). ArticleCASPubMed Google Scholar
Jiang, W., Bikard, D., Cox, D., Zhang, F. & Marraffini, L.A. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat. Biotechnol.31, 233–239 (2013). ArticleCASPubMedPubMed Central Google Scholar
Wu, Y. et al. Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9. Cell Stem Cell13, 659–662 (2013). ArticleCASPubMed Google Scholar
Schwank, G. et al. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell13, 653–658 (2013). ArticleCASPubMed Google Scholar
Dickinson, D.J., Ward, J.D., Reiner, D.J. & Goldstein, B. Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. Nat. Methods10, 1028–1034 (2013). ArticleCASPubMedPubMed Central Google Scholar
Qi, L.S. et al. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell152, 1173–1183 (2013). ArticleCASPubMedPubMed Central Google Scholar
Cheng, A.W. et al. Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cell Res.23, 1163–1171 (2013). ArticleCASPubMedPubMed Central Google Scholar
Mali, P. et al. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol.31, 833–838 (2013). ArticleCASPubMedPubMed Central Google Scholar
Pattanayak, V. et al. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol.31, 839–843 (2013). ArticleCASPubMedPubMed Central Google Scholar
Cradick, T.J., Fine, E.J., Antico, C.J. & Bao, G. CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity. Nucleic Acids Res.41, 9584–9592 (2013). ArticleCASPubMedPubMed Central Google Scholar
Chiu, H., Schwartz, H.T., Antoshechkin, I. & Sternberg, P.W. Transgene-free genome editing in Caenorhabditis elegans using CRISPR-Cas. Genetics195, 1167–1171 (2013). ArticleCASPubMedPubMed Central Google Scholar
Cho, S.W. et al. Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res.24, 132–141 (2014). ArticleCASPubMedPubMed Central Google Scholar
Fu, Y. et al. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol.31, 822–826 (2013). ArticleCASPubMedPubMed Central Google Scholar
Sternberg, S.H., Redding, S., Jinek, M., Greene, E.C. & Doudna, J.A. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. Nature507, 62–67 (2014). ArticleCASPubMedPubMed Central Google Scholar
Teytelman, L., Thurtle, D.M., Rine, J. & van Oudenaarden, A. Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins. Proc. Natl. Acad. Sci. USA110, 18602–18607 (2013). ArticleCASPubMedPubMed Central Google Scholar
Stadler, M.B. et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature480, 490–495 (2011). ArticleCASPubMed Google Scholar
Orioli, A. et al. Widespread occurrence of non-canonical transcription termination by human RNA polymerase III. Nucleic Acids Res.39, 5499–5512 (2011). ArticleCASPubMedPubMed Central Google Scholar
Nielsen, S., Yuzenkova, Y. & Zenkin, N. Mechanism of eukaryotic RNA polymerase III transcription termination. Science340, 1577–1580 (2013). ArticleCASPubMedPubMed Central Google Scholar
Jinek, M. & Doudna, J.A. A three-dimensional view of the molecular machinery of RNA interference. Nature457, 405–412 (2009). ArticleCASPubMed Google Scholar
Langmead, B., Trapnell, C., Pop, M. & Salzberg, S.L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol.10, R25 (2009). ArticlePubMedPubMed Central Google Scholar