Mahsa Ahmadi - Academia.edu (original) (raw)

Related Authors

Noe Cornago

University of the Basque Country, Euskal Herriko Unibertsitatea

Uploads

Papers by Mahsa Ahmadi

Introduction to the biogenic Ag nanozyme for the control and eradication of microbes and environmental pollutants

Materials Chemistry and Physics

Antiviral activity of biosynthesized copper nanoparticle by Juglans regia green husk aqueous extract and Iron nanoparticle: molecular docking and in-vitro studies

Iranian Journal of Microbiology

Background and Objectives: The interaction between nanoparticles (NPs) and viruses is attracting ... more Background and Objectives: The interaction between nanoparticles (NPs) and viruses is attracting interest because of the antiviral potential of NPs. This study aims to investigate the antiviral potential of NPs against Herpes simplex virus types 1 (HSV-1). Materials and Methods: Molecular docking studies were conducted by Molegro virtual docker software. An extract of Juglans regia green husk was utilized to biosynthesize copper-oxide nanoparticles (CuNPs). The cytotoxicity of NPs was evaluated by MTT assay. Different treatment assays were conducted. Another assay was designed to employ the concentration of 300 μg/ml of CuNPs, which is the highest concentration that did not precipitate. Finally, chemically synthesized Iron oxide nanoparticles (FeNPs) were utilized to adsorb CuNPs. The antiviral effect of FeNPs was investigated, separately. Results: Docking results confirmed that NPs could interact with the HSV-1 glycoproteins and prevent viral entry. MTT assay results illustrated th...

Mediterranean Journal of Infection, Microbes and Antimicrobials, Sep 16, 2021

Herpes simplex virus type-1 (HSV-1) is a prevalent pathogen that causes various outcomes from ora... more Herpes simplex virus type-1 (HSV-1) is a prevalent pathogen that causes various outcomes from oral and facial lesions to fatal encephalitis and herpetic keratitis. Acyclovir (ACV) is a current treatment option for HSV-1 infection. However, considering the emergence of ACV-resistant HSV-1 and the detrimental side effects of prolonged administration of ACV such as acute kidney injury, the development of novel antiviral therapeutic agents and new drug delivery systems appear indispensable. With the advent of nanotechnology, nanoparticles (NPs) have attracted great attention as antimicrobial agents and drug carriers because of their unique physical and chemical properties. This review focused on the antiviral activity of NPs against HSV-1 infection and their application in the delivery of ACV.

Guillain–Barre syndrome

Reviews in Medical Microbiology

Introduction to the biogenic Ag nanozyme for the control and eradication of microbes and environmental pollutants

Materials Chemistry and Physics

Antiviral activity of biosynthesized copper nanoparticle by Juglans regia green husk aqueous extract and Iron nanoparticle: molecular docking and in-vitro studies

Iranian Journal of Microbiology

Background and Objectives: The interaction between nanoparticles (NPs) and viruses is attracting ... more Background and Objectives: The interaction between nanoparticles (NPs) and viruses is attracting interest because of the antiviral potential of NPs. This study aims to investigate the antiviral potential of NPs against Herpes simplex virus types 1 (HSV-1). Materials and Methods: Molecular docking studies were conducted by Molegro virtual docker software. An extract of Juglans regia green husk was utilized to biosynthesize copper-oxide nanoparticles (CuNPs). The cytotoxicity of NPs was evaluated by MTT assay. Different treatment assays were conducted. Another assay was designed to employ the concentration of 300 μg/ml of CuNPs, which is the highest concentration that did not precipitate. Finally, chemically synthesized Iron oxide nanoparticles (FeNPs) were utilized to adsorb CuNPs. The antiviral effect of FeNPs was investigated, separately. Results: Docking results confirmed that NPs could interact with the HSV-1 glycoproteins and prevent viral entry. MTT assay results illustrated th...

Mediterranean Journal of Infection, Microbes and Antimicrobials, Sep 16, 2021

Herpes simplex virus type-1 (HSV-1) is a prevalent pathogen that causes various outcomes from ora... more Herpes simplex virus type-1 (HSV-1) is a prevalent pathogen that causes various outcomes from oral and facial lesions to fatal encephalitis and herpetic keratitis. Acyclovir (ACV) is a current treatment option for HSV-1 infection. However, considering the emergence of ACV-resistant HSV-1 and the detrimental side effects of prolonged administration of ACV such as acute kidney injury, the development of novel antiviral therapeutic agents and new drug delivery systems appear indispensable. With the advent of nanotechnology, nanoparticles (NPs) have attracted great attention as antimicrobial agents and drug carriers because of their unique physical and chemical properties. This review focused on the antiviral activity of NPs against HSV-1 infection and their application in the delivery of ACV.

Guillain–Barre syndrome

Reviews in Medical Microbiology

Log In