Actinonin, a Naturally Occurring Antibacterial Agent, Is a Potent Deformylase Inhibitor (original) (raw)

The Crystal Structures of Four Peptide Deformylases Bound to the Antibiotic Actinonin Reveal Two Distinct Types: A Platform for the Structure-based Design of Antibacterial Agents

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Antibiotic Activity and Characterization of BB3497, a Novel Peptide Deformylase Inhibitor

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A new human peptide deformylase inhibitable by actinonin

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Mechanism of Time-Dependent Inhibition of Polypeptide Deformylase by Actinonin

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Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin

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2002

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In Silico Study of the Selective Inhibition of Bacterial Peptide Deformylases by Several Drugs

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New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity

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New Antibiotic Molecules: Bypassing the Membrane Barrier of Gram Negative Bacteria Increases the Activity of Peptide Deformylase Inhibitors

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Non-streptomycete actinomycetes nourish the current microbial antibiotic drug discovery

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Deformylase as a novel antibacterial target

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Actinobacteria: From Biodiversity to Biotechnology

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Peptide Deformylase in Staphylococcus aureus: Resistance to Inhibition Is Mediated by Mutations in the Formyltransferase Gene

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Antimicrobial Agents and Chemotherapy, 2000

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Peptide Deformylase As An Antibacterial Drug Target: Target Validation and Resistance Development

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Antimicrobial agents …, 2001

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New Dimensions of Research on Actinomycetes: Quest for Next Generation Antibiotics

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Frontiers in Microbiology, 2016

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Update on Bioactive Molecules of Actinomycetes

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Biosciences Biotechnology Research Asia, 2014

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Exploration of Actinobacteria for Multifaceted Applications: Lessons to Learn from the Genome, Proteome and Metabolome of Pristine Microbial Majority

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