Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage (original) (raw)
Aggrecan Turnover in Human Articular Cartilage: Use of Aspartic Acid Racemization as a Marker of Molecular Age
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A comparison of different purification methods of aggrecan fragments from human articular cartilage and synovial fluid
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Influence of aging on the synthesis and morphology of the aggrecans synthesized by differentiated human articular chondrocytes
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The mechanism of aggrecan release from cartilage differs with tissue origin and the agent used to stimulate catabolism
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Biochemical Journal, 2002
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ELISA for the core protein of the cartilage large aggregating proteoglycan, aggrecan: Comparison with the concentrations of immunogenic keratan sulphate in synovial fluid, serum and urine
Jens-christian Poulsen
Clinica Chimica Acta, 1994
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Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants
Karena Last
2000
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Distribution of hyaluronan in articular cartilage as probed by a biotinylated binding region of aggrecan
Markku Tammi
Histochemistry and Cell Biology, 1996
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The structure of aggrecan fragments in human synovial fluid. evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis
John Sandy
Arthritis & Rheumatism, 1993
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Aggrecan heterogeneity in articular cartilage from patients with osteoarthritis
William Fisher
BMC musculoskeletal disorders, 2016
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Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments1
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Osteoarthritis and Cartilage, 2006
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Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2)
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Arthritis & Rheumatism, 2004
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Molecular and Biochemical Assays of Cartilage Components
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Cartilage and Osteoarthritis, 2004
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Peter Roughley
European cells & materials, 2006
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Immunohistochemical localization of articular cartilage proteoglycan and link protein in situ using monoclonal antibodies and lectin-binding methods
Sibylle Hoedt-Schmidt
Histochemistry, 1993
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Proteoglycan aggregates in adult human costal cartilage
jeffrey Pearson
Biochimica et Biophysica Acta (BBA) - General Subjects, 1979
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Coincubation of Bovine Synovial or Capsular Tissue with Cartilage Generates a Soluble “Aggrecanase” Activity
David Buttle
Biochemical and Biophysical Research Communications, 1999
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Comparison of proteoglycans from bovine articular cartilage
Subhash pal Subhash pal
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1975
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Aggrecanase" activity is implicated in tumour necrosis factor alpha mediated cartilage aggrecan breakdown but is not detected by an in vitro assay
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Molecular Pathology, 1997
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Histochemistry of glycosaminoglycans in cartilage ground substance
Silvana Geleff
Histochemistry, 1986
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Biochemical Journal, 1980
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Turnover of proteoglycans in cultures of bovine articular cartilage
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Biochemical and morphologic studies of cartilage from the adult human sacroiliac joint
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Arthritis & Rheumatism, 1983
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Aggrecanase: A Target for the Design of Inhibitors of Cartilage Degradation
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Annals of the New York Academy of Sciences, 1999
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The High Molecular Weight Cat-301 Chondroitin Sulfate Proteoglycan from Brain Is Related to the Large Aggregating Proteoglycan from Cartilage, Aggrecan
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Chemical and Immunological Assay of the Nonreducing Terminal Residues of Chondroitin Sulfate from Human Aggrecan
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Journal of Biological Chemistry, 1997
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The Interglobular Domain of Cartilage Aggrecan Is Cleaved by Hemorrhagic Metalloproteinase HT-d (Atrolysin C) at the Matrix Metalloproteinase and Aggrecanase Sites
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Proteoglycan Structure and Metabolism in Normal and Osteoarthritic Cartilage of Guinea Pigs
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Age-related changes in the sulphation of the chondroitin sulphate linkage region from human articular cartilage aggrecan
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Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro
Peter Roughley
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An enzyme-linked immunoassay for the cartilage proteoglycan
V. Hascall
Archives of Biochemistry and Biophysics, 1981
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Fixation, decalcification, and tissue processing effects on articular cartilage proteoglycans
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