Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6 (original) (raw)

a Novel Inducer of Blimp1 and Bcl6 and Plasma Cell Generation by IL21, Regulation of B Cell Differentiation

Rosanne Spolski

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The role of IL-21 in regulating B-cell function in health and disease

Stefan Kuchen

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IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from human marginal zone B cells as well as from circulating peripheral blood B cells from autoimmune patients

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B Cells Pathways Induced by IL21 in Human Intermediates and Molecular Identification of Cellular

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IL-21 is the primary common chain-binding cytokine required for human B-cell differentiation in vivo

Joanne Smart

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IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus–like Disease of BXSB.Yaa Mice

Thomas Sproule

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IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus-like Disease of BXSB.Yaa Mice

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IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice

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IL-21 Regulates the Differentiation of a Human γδ T Cell Subset Equipped with B Cell Helper Activity

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IL22, in contrast to IL10, does not induce Ig production, due to absence of a functional IL22 receptor on activated human B cells

Martin Garcia

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A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

Rosanne Spolski

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IL-21 induces death of marginal zone B cells during chronic inflammation

Christoph Mueller

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into Antibody-Secreting Plasma Cells Human Naive and Memory B Cells IL21 Induces Differentiation of

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IL-21 and CD40L Synergistically Promote Plasma Cell Differentiation through Upregulation of Blimp-1 in Human B Cells

Hongshan Chen

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IL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivo

Morton Cowan

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Follicular Helper Cells T + of IL21 Produced by CXCR5 Ig-Secreting Cells: Predominant Role Human B Cell Differentiation into Cytokine-Mediated Regulation of

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Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells

Sandrine Lécart

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Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

Stefan Kuchen

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Inflammation In Vivo and In Vitro Roles of IL-21 in

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Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

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IL-21 Induces Differentiation of Human Naive and Memory B Cells into Antibody-Secreting Plasma Cells

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Faculty of 1000 evaluation for The cellular source and target of IL-21 in K/BxN autoimmune arthritis

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Therapy implications for the role of IL-21 in lupus

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Expert Review of Clinical Immunology, 2016

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IL-21 ensures TGF-β1-induced IgA isotype expression in mouse Peyer’s patches

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IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

Shane Crotty

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IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

Mark Smyth

Journal of Experimental Medicine, 2010

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Cutting Edge: IL-21 Derived from Human Follicular Helper T Cells Acts as a Survival Factor for Secondary Lymphoid Organ, but Not for Bone Marrow, Plasma Cells

Beatriz Rodríguez Bayona

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IL-21 Induces Apoptosis of Antigen-Specific CD8+ T Lymphocytes

Brianne Barker

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IL-21: a novel IL-2–family lymphokine that modulates B, T, and natural killer cell responses

Tarek Habib

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IL-21 Mediates Suppressive Effects via Its Induction of IL-10

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IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts

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