Identification of the glucagon receptor by covalent labeling with a radiolabeled photoreactive glucagon analog (original) (raw)
Binding of a glucagon photoaffinity label to rat liver plasma membranes and its effect on adenylate cyclase activity before and after photolysis
Richard Epand
Biochemistry, 1982
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Direct Evidence of a Glucagon-Dependent Regulation of the Concentration of Glucagon Receptors in the Liver
Angel Santos
European Journal of Biochemistry, 1982
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The glucagon receptor of rat liver plasma membrane can couple to adenylate cyclase without activating it
Robin Hesketh
Biochimica Et Biophysica Acta-biomembranes, 1976
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Structural requirements for glucagon receptor binding and activation of adenylate cyclase in liver. Study of chemically modified forms of the hormone, including N alpha-trinitrophenyl glucagon, an antagonist
Richard Epand
The Journal of biological chemistry, 1981
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Binding and biologic activity of glucagon in liver cell membranes of chronically hyperglucagonemic rats
Coimbatore Srikant
Journal of Biological Chemistry
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Antibodies against specific extracellular epitopes of the glucagon receptor block glucagon binding
Aaron Cypess
Proceedings of the National Academy of Sciences, 1996
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Physiological effect of circulating glucagon on the hepatic membrane potential
Erwin Scharrer
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2001
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Non-equivalence of the carboxyl groups of glucagon in the carbodiimide-promoted reaction with nucleophiles and the role of carboxyl groups in the ability of glucagon to stimulate the adenyl cyclase of rat liver
Richard Epand
Biochimica et Biophysica Acta (BBA) - General Subjects, 1974
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Receptor binding and adenylate cyclase activities of glucagon analogs modified in the N-terminal region
Victor Hruby
Biochemistry, 1986
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Characterization of glucagon‐like peptide‐I(7–36)amide receptors of rat lung membranes by covalent cross‐linking
Burkhard Göke
FEBS Letters, 1991
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Effect of specific trinitrophenylation of the lysine epsilon amino group of glucagon on receptor binding and adenylate cyclase activation
Richard Epand
Archives of Biochemistry and Biophysics, 1983
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Divalent cations regulate glucagon binding. Evidence for actions on receptor-N/sub s/ complexes and on receptors uncoupled from N/sub s/
Robert Maki
1988
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Development of a radiolabeled glucagon compound for imaging
Alireza Doroudi
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Divalent cations regulate glucagon binding. Evidence for actions on receptor-Ns complexes and on receptors uncoupled from Ns
Robert Maki
Biochemistry, 1988
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Inhibition by glucagon of the calcium pump in liver plasma membranes
Richard Epand
The Journal of biological chemistry, 1984
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Identification of glucagon in the gastrointestinal tract
Coimbatore Srikant
Journal of Clinical Investigation, 1975
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Stimulation and inhibition of cAMP accumulation by glucagon in canine hepatocytes
Victor Hruby
Journal of Biological Chemistry, 1987
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Glucagon binding to receptors on the surface of chicken adipocytes
Patrick Oscar
Journal of Animal Science, 1995
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Structure activity studies on the N-terminal region of glucagon
Valentine Lance
Journal of Medicinal Chemistry, 1984
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Glucagon-(19-29), a Ca2+ pump inhibitory peptide, is processed from glucagon in the rat liver plasma membrane by a thiol endopeptidase
nguyen le
Journal of Biological Chemistry, 1990
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Synthesis and expression of a gene for the rat glucagon receptor. Replacement of an aspartic acid in the extracellular domain prevents glucagon binding
C. Carruthers, Cecilia Unson
The Journal of biological chemistry, 1994
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N-Ethylmaleimide uncouples the glucagon receptor from the regulatory component of adenylyl cyclase
Kenneth Lipson
Biochemistry, 1986
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Evaluation of Commercially Available Glucagon Receptor Antibodies and Glucagon Receptor Expression
Reidar Albrechtsen
2021
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Fate of injected glucagon taken up by rat liver in vivo. Degradation of internalized ligand in the endosomal compartment
Florence Lederer
Biochemical Journal, 1990
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Receptor binding of glucagon and adenosine 3′,5′-monophosphate accumulation in isolated rat fat cells
Ole Sonne
Biochimica et Biophysica Acta (BBA) - General Subjects, 1977
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Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method
Pascale Vertongen
Peptides, 2011
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Absence of insulinotropic glucagon-like peptide-I(7–37) receptors on isolated rat liver hepatocytes
Svetlana Mojsov
FEBS Letters, 1991
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Effect of glucagon on insulin receptor phosphorylation in intact liver cells
Tarik Issad
FEBS Letters, 1992
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Conformational and biological properties of glucagon fragments containing residues 1-17 and 19-29
Richard Epand
International Journal of Peptide and Protein Research, 1983
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Insulin receptor: Interaction with nonreceptor glycoprotein from liver cell membranes
Morley Hollenberg
Proceedings of the National Academy of Sciences, 1978
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Glucagon acts through its own receptors in the presence of functional glucagon-like peptide-1 receptors on hamster insulinoma
Jean-claude Marie
Endocrinology, 1996
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Semisynthetic glucagon derivatives for structure-function studies
Victor Hruby
Metabolism, 1976
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Roles of Specific Extracellular Domains of the Glucagon Receptor in Ligand Binding and Signaling †
Cecilia Unson
Biochemistry, 2002
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Glucagon receptor recycling: role of carboxyl terminus, -arrestins, and cytoskeleton
Cecilia Unson
AJP: Cell Physiology, 2008
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The relation of structure to storage and receptor binding of glucagon
Tom Blundell
Metabolism, 1976
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