Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis (original) (raw)
Generating long-lived CD8+T-cell memory: Insights from epigenetic programs
Hossam Abdelsamed
European Journal of Immunology, 2016
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Epigenetic Maintenance of Acquired Gene Expression Programs during Memory CD8 T Cell Homeostasis
Hossam Abdelsamed
Frontiers in Immunology, 2018
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Cutting Edge: Chromatin Remodeling as a Molecular Basis for the Enhanced Functionality of Memory CD8 T Cells
John K. Northrop, MD, PhD
The Journal of Immunology, 2008
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Epigenetic Remodeling of theIL-2andIFN-γ Loci in Memory CD8 T Cells Is Influenced by CD4 T Cells
John K. Northrop, MD, PhD
The Journal of Immunology, 2006
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Plasticity of DNA methylation in mouse T cell activation and differentiation
Stephen Ohms
BMC Molecular Biology, 2012
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Histone H3K27 Demethylase Negatively Controls the Memory Formation of Antigen-Stimulated CD8+ T Cells
Yuuki Imai
The Journal of Immunology
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DNA Methylation by DNA Methyltransferase 1 Is Critical for Effector CD8 T Cell Expansion
John Altman
The Journal of Immunology, 2006
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Lineage relationship of CD8+ T cell subsets is revealed by progressive changes in the epigenetic landscape
Manikandan Narayanan
Cellular and Molecular Immunology, 2015
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Origin and differentiation of human memory CD8 T cells after vaccination
Hossam Abdelsamed
Nature, 2017
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T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate
David Hildeman
Cell Death & Differentiation, 2019
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Curtailed T-cell activation curbs effector differentiation and generates CD8(+) T cells with a naturally-occuring memory stem cell phenotype
Alessandra Roberto
European journal of immunology, 2017
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Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development
Thomas Ulas
Immunity, 2016
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Lineage relationships, homeostasis, and recall capacities of central– and effector–memory CD8 T cells in vivo
Philippe Kourilsky
Journal of Experimental Medicine, 2005
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Epitope Density Influences CD8+ Memory T Cell Differentiation
Juju Gmail
PloS one, 2010
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Signals for antigen-independent differentiation of memory CD8+ T cells
Eliza Mari Kwesi-Maliepaard
Cellular and molecular life sciences : CMLS, 2021
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Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development
Sema Kurtulus
Frontiers in Immunology, 2013
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Lineage relationship and protective immunity of memory CD8 T cell subsets
Rafi Ahmed
Nature Immunology, 2003
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Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
Surojit Sarkar
Journal of Experimental Medicine, 2008
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A genome-wide regulatory network identifies key transcription factors for memory CD8+ T-cell development
Jianzhu Chen
Nature Communications, 2013
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Epigenetic control of CD8+T cell tissue homing and tissue resident memory T cell precursors by the histone methyltransferase SUV39H1
Jaime Fuentealba
bioRxiv (Cold Spring Harbor Laboratory), 2024
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Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
M. Edinger
Genome Research, 2009
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Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes
Pärt Peterson
Scientific Reports, 2015
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In vitro Homeostatic Proliferation of Human CD8 T Cells
Hossam Abdelsamed
BIO-PROTOCOL, 2017
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Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation
Charmaine Brown
Cell Reports, 2021
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The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells
Eliza Mari Kwesi-Maliepaard
2019
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DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine
Subhasis Mohanty, Ruth R Montgomery
Journal of immunology (Baltimore, Md. : 1950), 2015
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CD8+ T Cells Sabotage Their Own Memory Potential through IFN- -Dependent Modification of the IL-12/IL-15 Receptor Axis on Dendritic Cells
Andrew Zloza, Tamson Moore, Jeremy O’Sullivan
The Journal of Immunology, 2012
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CD8 T cell memory: it takes all kinds
Sara Hamilton
Frontiers in immunology, 2012
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Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation
David Blair
Nature Immunology, 2013
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CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia
Charmaine Brown
Cell Reports, 2021
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Activated-memory T cells influence naive T cell fate: A novel non-cytotoxic function of human CD8 T cells
Hossam Abdelsamed
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A committed tissue-resident memory T cell precursor within the circulating CD8+ effector T cell pool
Jos Urbanus
Journal of Experimental Medicine
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Mapping histone methylation dynamics during virus-specific CD8+ T cell differentiation in response to infection
Jolie Cullen
Immunity, 2017
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CD137 (4-1BB) costimulation modifies DNA methylation in CD8+ T-cell relevant genes
Juan Sandoval
Cancer immunology research, 2017
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