{"content"=>"IL-21 drives expansion and plasma cell differentiation of autoreactive CD11cT-bet B cells in SLE.", "sup"=>[{"content"=>"hi"}, {"content"=>"+"}]} (original) (raw)

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

Rosanne Spolski

Proceedings of the National Academy of Sciences, 2009

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Therapy implications for the role of IL-21 in lupus

davide di fusco

Expert Review of Clinical Immunology, 2016

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IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus–like Disease of BXSB.Yaa Mice

Thomas Sproule

Journal of Immunology, 2013

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IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus-like Disease of BXSB.Yaa Mice

Thomas Sproule

The Journal of Immunology, 2013

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Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus

Johanna Westra, Wayel Abdulahad

Arthritis Research & Therapy, 2011

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IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice

Quintus Medley, Heath Guay

The Journal of Immunology, 2012

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Interleukin-21 Receptor Blockade Inhibits Secondary Humoral Responses and Halts the Progression of Preestablished Disease in the (NZB × NZW)F1 Systemic Lupus Erythematosus Model

Palaniswami Rathanaswami

Arthritis & rheumatology, 2015

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IL-21R blockade inhibits secondary humoral responses and halts the progression of pre-established disease in NZB/W F1 systemic lupus erythematosus

Palaniswami Rathanaswami

Arthritis & rheumatology (Hoboken, N.J.), 2015

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IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage inlyn−/−mice

Toñi Gutiérrez

European Journal of Immunology, 2012

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Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R

Kitti Pazmandi

International Journal of Molecular Sciences

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ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

Amanda Poholek

Journal of Experimental Medicine, 2008

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The role of IL-21 in regulating B-cell function in health and disease

Stefan Kuchen

Immunological Reviews, 2008

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B-cell-attracting chemokine CXCL13 as a marker of disease activity and renal involvement in systemic lupus erythematosus (SLE)

Hermann Haller

Nephrology Dialysis Transplantation, 2009

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IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from human marginal zone B cells as well as from circulating peripheral blood B cells from autoimmune patients

A. Grammer

Arthritis Research & Therapy, 2007

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T Follicular Helper Cells Mediate Expansion of Regulatory B Cells via IL-21 in Lupus-Prone MRL/lpr Mice

Yiwei Chu

PLoS ONE, 2013

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Faculty of 1000 evaluation for The cellular source and target of IL-21 in K/BxN autoimmune arthritis

Jason McDougall

F1000 - Post-publication peer review of the biomedical literature, 2014

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Dysfunctional B cells in systemic lupus erythematosus

Christophe Jamin, Yves Renaudineau, Jacques-olivier Pers

Autoimmunity Reviews, 2004

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IL-21 is the primary common chain-binding cytokine required for human B-cell differentiation in vivo

Joanne Smart

Blood, 2011

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Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6

Daniel Shaffer

The Journal of Immunology, 2004

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Expanded Population of Activated Antigen-Engaged Cells within the Naive B Cell Compartment of Patients with Systemic Lupus Erythematosus

D. Gladman

The Journal of Immunology, 2008

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Differential control of CD22 ligand expression on B and T lymphocytes, and enhanced expression in murine systemic lupus

Liliane Fossati-Jimack

Arthritis & Rheumatism, 2003

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T Follicular Helper Cells and Regulatory B Cells Dynamics in Systemic Lupus Erythematosus

Yiwei Chu

PLoS ONE, 2014

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CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

Edward A Clark

Frontiers in immunology, 2018

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The Role of B-Cells and B-Cell Targeted Therapies in Lupus Nephritis

Marta Blanco

Diseases of Renal Parenchyma, 2012

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Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse

Kaoru Tanaka

Immunology Letters, 2012

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In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis

Anthony Chang

The Journal of Immunology, 2011

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A novel subpopulation of B1 cells is enriched with autoreactivity in normal and lupus-prone mice

Wenda Gao

Arthritis and Rheumatism, 2009

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Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease

Thomas Sproule

Cell reports, 2017

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Meant to B: B cells as a therapeutic target in systemic lupus erythematosus

betty diamond

Journal of Clinical Investigation, 2021

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The role of B cells in lupus pathogenesis

betty diamond

The International Journal of Biochemistry & Cell Biology, 2010

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Autoantibody-dependent and autoantibody-independent roles for B cells in systemic lupus erythematosus: Past, present, and future

William Stohl

Autoimmunity, 2010

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Cd22a PRE-mRNA Dysregulated Expression of the Cd22 Gene as a Result of a Short Interspersed Nucleotide Element Insertion in Cd22a Lupus-Prone Mice

Daniel Parzy

The Journal of Immunology, 2000

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B-cell Biology and Related Therapies in Systemic Lupus Erythematosus

Sadia Ahmed

Rheumatic Disease Clinics of North America, 2010

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into Antibody-Secreting Plasma Cells Human Naive and Memory B Cells IL21 Induces Differentiation of

Rachel Fairhurst

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a Novel Inducer of Blimp1 and Bcl6 and Plasma Cell Generation by IL21, Regulation of B Cell Differentiation

Rosanne Spolski

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