The Tau N279K Exon 10 Splicing Mutation Recapitulates Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Tauopathy in a Mouse Model (original ) (raw )Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease
Jonathan Samuel
Proceedings of the National Academy of Sciences, 2003
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Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders
Max Holzer
Molecular Brain Research, 1999
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Tau with three and four microtubule-binding repeats in human brain of Alzheimer's disease and frontotemporal dementia
Nenad Bogdanovic
Neurobiology of Aging, 2000
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Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17
G. Varani
Proceedings of the National Academy of Sciences, 1999
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Microtubule-dependent Oligomerization of Tau: IMPLICATIONS FOR PHYSIOLOGICAL TAU FUNCTION AND TAUOPATHIES
victoria makrides
Journal of Biological Chemistry, 2003
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Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration
Mary Jordan
Molecular Biology of the Cell, 2004
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Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
Yann Verdier
Scientific Reports, 2015
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Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains
Jennifer Osetek
Acta Neuropathologica, 2007
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FTDP-17 Mutations Compromise the Ability of Tau to Regulate Microtubule Dynamics in Cells
Mary Jordan
Journal of Biological Chemistry, 2006
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Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
Caroline Smet-Nocca
Frontiers in Aging Neuroscience
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Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies
Abdala Ussif
Molecular and Cellular Neuroscience, 2017
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Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy
Juan Ferrario
Cell reports, 2018
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Atypical, non-standard functions of the microtubule associated Tau protein
Marie-christine Galas
Acta neuropathologica communications, 2017
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Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects
Bernard Schneider
Scientific reports, 2017
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High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the Netherlands
rivka ravid
American Journal of Human Genetics, 1999
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FTDP-17 Mutations in Tau Alter the Regulation of Microtubule Dynamics
Mary Jordan
Journal of Biological Chemistry, 2008
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Tau protein in neurodegenerative diseases - a review
simona bondari
2017
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Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy
Magdalena De León
Brain, 2021
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Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
Mohamed Senouci
Proceedings of the National Academy of Sciences, 1998
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Oligomerization of the Microtubule Associated Protein Tau is Mediated by its N-Terminal Sequences: Implications for Normal and Pathological Tau Action
Srinivasan Ramachandran
Journal of neurochemistry, 2016
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Three- and Four-repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners
Mary Jordan
Journal of Biological Chemistry, 2005
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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work
Valérie Buée-Scherrer
Brain Research Reviews, 2000
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SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy
Juan Ferrario
Frontiers in Bioengineering and Biotechnology
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A genomic sequence analysis of the mouse and human microtubule-associated protein tau
Yang Zhou
Mammalian Genome, 2001
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Familial FTDP-17 Missense Mutations Inhibit Microtubule Assembly-promoting Activity of Tau by Increasing Phosphorylation at Ser202 in Vitro
Hamid Yaqoob Qureshi
Journal of Biological Chemistry, 2009
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Tau-based treatment strategies in neurodegenerative diseases
Anja Schneider
Neurotherapeutics, 2008
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Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
Katerina Markopoulou
Proceedings of the National Academy of Sciences, 1998
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A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration
Zbigniew Wszolek
Neurology, 1999
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Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability
Frida Kleiman
Frontiers in cellular neuroscience, 2018
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Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau
Lidia Bakota
Frontiers in Neurology, 2020
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