Effect of alkylating antitumor agents on the binding of DNA to protein (original) (raw)

Mechanism of inhibition of DNA synthesis in Ehrlich ascites tumour cells by diazoacetyl glycine-amide

Tullio Giraldi

Biochemical Pharmacology, 1973

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The effects of bifunctional alkylating anti-tumor agents on oncogene structure and function in the human tumor cell line Colo 3320 HSR

Bernard Futscher

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Detection of sequence-specific antitumor alkylating agent DNA damage from cells treated in culture and from a patient

George Ogata

Cancer research, 1994

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Alkylating agent interactions with the nuclear matrix

Philip Schein, MD DSc(hon)

Biochemical Pharmacology, 1983

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Studies on DNA repair in human lymphocytes treated with proximate carcinogens and alkylating agents

Stewart Sell

Cancer Research

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Utilization of in vivo alkylated metabolites as a possible cause of increased sensitivity of tumor cells to alkylating agents

Michael Lerman

Molecular Biology Reports, 1975

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An inhibitor of DNA-synthesis, isolated from rat tumor-induced ascites

Jens Krøll

Virchows Archiv B Cell Pathology Including Molecular Pathology, 1982

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The antitumour activity of alkylating agents is not correlated with the levels of glutathione, glutathione transferase and O6-alkylguanine-DNA-alkyltransferase of human tumour xenografts

Maurizio D'Incalci

European Journal of Cancer, 1998

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Human O6-alkylguanine-DNA alkyltransferase: protection against alkylating agents and sensitization to dibromoalkanes

carmen pueyo

Carcinogenesis, 1999

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The interaction of chromatin with alkylating agents. The monofunctional action of bis(2-chloroethyl)methylamine

aharon Yerushalmi

European journal of biochemistry / FEBS, 1980

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Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells

Neil Gibson

Cancer research, 1984

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DNA alkylation in the hamster induced by two pancreatic carcinogens

Demetrius Kokkinakis

Cancer research, 1989

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Effects of the antitumor drugs 3-nitrobenzothiazolo {3,2-a}quinolinium and fagaronine on nucleic acid and protein synthesis

Adriana Báez

Biochemical Pharmacology, 1986

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Mutagenic and chemotherapeutic activity in L1210 leukemia of several monofunctional alkylating agents

Bipin Mehta

Cancer research, 1985

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Exposure of HeLa cells to 06-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents

Christopher Corsico

Biochemical and Biophysical Research Communications, 1985

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Repair of O6-alkylguanines in the nuclear DNA of human lymphocytes and leukaemic cells: analysis at the single-cell level

Michael Mueller

British Journal of Cancer, 1994

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Differences in the rate of destruction of alkylated RNA, protein, and lipid molecules in normal and tumor cells

Michael Lerman

Bulletin of Experimental Biology and Medicine, 1973

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Effect of chlorambucil on synthesis of protein and nucleic acids in tumor-bearing mice

Sanchari Pradhan

Cancer research, 1960

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DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase

James Hartley

British journal of cancer, 1997

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Binding of chlorozotocin and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea to chromatin and nucleosomal fractions of HeLa cells

Philip Schein, MD DSc(hon)

Cancer Research

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Interaction of the Alkylating Antitumor Agent 2,3,5Tris(ethyleneimino)- benzoquinone with the Plasma Membrane of Ehrlich Ascites Tumor Cells1

Michael Harrer

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Sedimentation of DNA from L1210 cells after treatment with 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) or 1-beta-D-arabinofuranosylcytosine or both drugs

Charles Peck

Cancer research, 1980

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Alkylating agents induced secondary malignancies -A review

QUEST JOURNALS

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ALTERATIONS IN 3H-THYMIDINE INCORPORATION INTO DNA INDUCED BY METHYL CCNU [1-(2-CHLOROETHYL)-3-(4METHYL CYCLOHEXYL)-1NITROSOUREA] IN NORMAL AND TUMOROUS TISSUES IN VIVO

Diana Goldberg

Cell Proliferation, 1976

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Mammalian 06-Alkylguanine-DNA Alkyltransferase: Regulation and Importance in Response to Alkylating Carcinogenic and Therapeutic Agents

Anthony Pegg

1990

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DNA binding activity and inhibition of DNA-protein interactions

Enea Menegatti

Biochemical Pharmacology, 1992

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Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes

Kunihiko Sakumi

Proceedings of the National Academy of Sciences, 1998

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Preservation of DNA integrity in human and mouse leukemic cells induced to terminally differentiate by chemical agents

kurt kohn

Developmental Biology, 1981

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The Alkylating Agent, Dimethyl Sulphate, Stimulates ADP-Ribosylation of Histone H1 and Other Proteins in Permeabilised Mouse Lymphoma (L1210) Cells

Sydney Shall

European Journal of Biochemistry, 1982

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Relationships between the formation of O6-methyldeoxyguanosine by 1-p-carboxyl-3,3-dimethylphenyltriazene in DNA and O6-alkylguanine-DNA alkyltransferase in human peripheral leukocytes

Siow-ming Lee

Cancer research, 1994

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Effect of alkylation with streptozotocin on the secondary structure of DNA

Md. Ashikur Rahman 142-11-3813

Bioscience Reports, 1986

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Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine

Jason Yang

Cancer Chemotherapy and Pharmacology, 1989

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Mechanism of H-ras Oncogene Activation in Mouse Squamous Carcinoma Induced by an Alkylating Agent1

Sy Garte

Cancer Research, 1988

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