Method Based on Solid Phase Extraction, LC and GC for Analysis of Bisphenol A in Drinking Water (original) (raw)
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Tropical Journal of Pharmaceutical Research, 2012
To assess whether bisphenol A contamination occurred in seven brands of bottled drinking water in Riyadh, Saudi Arabia. Methods: Liquid-liquid extraction (using dichloromethane) was used to analytically extract bisphenol A from drinking water bottles and a gas chromatograph-mass spectrometer was employed for its detection using a splitless capillary column and helium as the carrier gas. Results: The concentration of bisphenol A (BPA) was high in all the bottled water brands tested. The mean concentration of BPA of the bottled water stored indoors (4.03 ng/L) was significantly lower than that stored outdoors (7.5 ng/L). Conclusion: Our results show that significant amounts of BPA leached from bottle containers into the water. Long storage of bottled water under direct sunlight should be avoided to reduce the risk of human exposure to BPA.
Endocrine disrupting Bisphenol A detection in different water samples in Iraq
Journal of Physics: Conference Series, 2019
Poly-carbonate plastics containing endocrine disruptor BPA (Bisphenol A), it have been used in the production process of water bottles, food products containers to storage, infants feeding milk bottles and raw material for some medical supplies. Trace quantity of bisphenol has been measured in water-samples that kept in poly-carbonate containers. It has been recognized that bisphenol a can be generated from poly-carbonate containers and then transfer into stored food. Such transfer is accelerated by leaving the containers in sunlight for long time. In this study a simple and rapid method was established to quantify BPA using high performance liquid chromatography (HPLC) in water samples in Al-Diwaniah city, Iraq. The chromatographic HPLC separation includes, extraction then detection of BPA using C18 as a HPLC column, followed by quantitative determination BPA using pre-measured known concentration as a standard. The analysis method shows a recovery value around 85% ± 2.9. A suitable sensitivity value was obtained with an instrumental limit of detection and quantification (LOD and LOQ) ranged from 33 to 72 µgL-1. The detection of BPA was effectively achieved using homemade and commercially supplied samples. The obtained numbers were inside the allowable concentration
2015
Bisphenol A (BPA) and its structural analogues (BPF, BPS, BPP, BPZ, BADGE, BPAF, BPAP) are used in the production of polycarbonate plastics and epoxy resins. Most of them have proven endocrine disruptive effects in humans and in other life forms in very low concentrations. BPA is of particular interest as it is mass produced and released into the environment as a result of human activity and accumulates in aquatic and terrestrial environments. Recent studies have revealed the presence of BPA in fresh water resources which is not only a threat to the fresh water ecosystems but also to humans because the usual source of drinking water is from rivers and streams. Presence of bisphenols in the environment is crucial and use of analytical techniques for their chemical separation and subsequent analysis is necessary for efficient environmental monitoring of these compounds. This study used capillary electrophoresis (CE) and liquid chromatography-mass spectrometry (LC/MS) to develop sensit...
Food Science and Technology
Bisphenol A (BPA) is a hazardous contaminant demonstrating endocrine disrupting properties, and assumed to be involved in the pathogenesis of various cancer diseases for instance prostate, lung and breast cancer. The objective of the present study was to estimate the BPA amounts in carbonated beverages from the Saudi Arabian market for the first time using an authenticated technique based on solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry. A total of thirty-four carbonated beverages of different flavors, origin and packaging materials were studied. The beverage production periods were from February 2018 to July 2018 containing volume (250-1000 mL), packaging materials were of canned, glass and polyethylene terephthalate (PET) plastic. BPA amounts in canned (0.64-11.41 µg/L), glass bottled (1.92-29.56 µg/L) and PET plastic bottled (0.37-21.83 µg/L) were obtained with recovery (97.64-99.96%). Relatively, glass bottled has offered higher amounts of BPA compared to PET plastic bottled and canned samples. The unforeseen presence of BPA especially in glass bottled emphasizes the ubiquity of such compound beside the food fabrication chain, far off to the food packaging materials. Thus, a further knowledge on BPA amounts in glass bottled samples, in addition to threat assessment studies, is essential to defend human health.
Influence of Temperature on the Quantity of Bisphenol A in Bottled Drinking Water
International Journal of Environmental Research and Public Health
Bisphenol A (BPA) is a component used in the production of polycarbonate plastics (PC) and epoxy resins, which are currently widely used in food and beverage packaging. Although BPA is not used in polyethylene terephthalate (PET) manufacturing, a recent study reported its presence in PET water bottles. This study was conducted to investigate the effects of storage conditions on the release of BPA from PET bottles as well as to assess health risks associated with the consumption of bottled water. Using high-performance liquid chromatography (HPLC), we measured the content of BPA in local brands of plastic bottled water sold in the Polish market. It has been established that temperature is one of the main factors that influences the migration of bisphenol A to products, as was confirmed by determination of the amount of bisphenol A in water, which was carried out without exposing the bottles to different temperatures. Despite the fact that the individual concentrations of BPA in bottl...
International Journal of Environmental Analytical Chemistry, 2020
This study investigated the release of a known endocrine disruptorbisphenol A (BPA), in drinking water and carbonated drinks stored in polycarbonate bottles and exposed to sunlight with a view of assessing the health risk involved in their consumption. BPA in the samples was extracted using solid-phase extraction method and determined with high performance liquid chromatography equipped with ultraviolet detector. Results showed that there were significant increase (p < 0.05) in BPA concentration of bottled water and carbonated drink exposed at 1, 3, 7 and 21 days. Also, there were enrichment of BPA levels ranging 31-868% in the bottled water and 17-920% carbonated drinks from 1 to 60 days when compared with the control. However, BPA migrating rate decreases with increase in exposure duration and later remains fairly constant as exposure duration progresses. The chronic daily intake of BPA in carbonated drinks and bottled water were low. The health risk index of BPA in polycarbonate bottled carbonated drinks and water was less than one in both adult and child and thus, there may be no probable adverse health effect on consumers of such products. However, caution should be taken as BPA is also released from other food packaging materials.
2018
Introduction: Bisphenol A (BPA) is a controversial plastics ingredient used mainly in the production of polycarbonate plastics (PC) and epoxy resins that widely used nowadays in food and drink packaging. Even though BPA is not involved in polyethylene terephthalate (PET) manufacturing, recent study had reported the present of BPA in PET water bottle. This study was conducted to investigate effects storage conditions on release of BPA from PC and PET bottled water as well as to assess health risks associated with consumption. Methods: Solid phase extraction (SPE) was used to extract the samples, followed by analysis using ultra high performance liquid chromatography with fluorescence detector (UHPLC-FLD). The possibility of developing chronic non-carcinogenic health risk among consumers of bottled water was evaluated using hazard quotient (HQ). Results: Results showed that BPA migrated from PC and PET water bottles at concentrations ranging from 9.13 to 257.67 ng/L and 11.53 ng/L to ...
Determination of bisphenol a in baby bottles and drinking containers by high liquid chromatography
Acta Periodica Technologica, 2019
Bisphenol A is a monomer used primarily in the production of polycarbonate plastics and epoxy resins. Polycarbonate plastic is used in a wide variety of digital media products, electrical and electronic equipment, sport safety equipment, reusable food and drink containers, etc. Epoxy resins are used in engineering applications, paints and adhesives and also in a variety of protective coatings in metal cans for foods, bottle tops and water supply pipes. The content of BPA was evaluated in 16 samples (6 baby bottles and 10 drinking containers - can) collected during 2018/2019, of which three baby bottles and 8 cans were collected in 2018, while three baby bottles and 2 cans in 2019. A simple HPLC-FLD analytical method was validated for the quantitation of BPA from baby feeding bottles and cans. The separation was performed on a C18 column. Good linearity was obtained over the concentration range of 0.3-6.0 ?g/mL with the regression coefficient (R2) of 0.9998. The limit of detection (L...
Journal of Chromatography a, 2004
We have developed a simple HPLC method for the microanalysis of bisphenol A (BPA), which is often contained in environmental water and is known as an endocrine disrupter. HPLC coupled with electrochemical detection requires a simpler procedure of pretreatment compared to GC-MS. In this study, we analyzed BPA using molecularly imprinted polymer as an on-line pretreatment device. This polymer has molecular recognition sites and provides specific selectivity in extraction process. Due to this effect, the detection limit obtained with this HPLC was 0.36 ng/l. This method applied to environmental water and purified water samples containing 2-70 ng/l of BPA successfully. Furthermore, UV detection was performed in some actual analyses.
Endocrine-disrupting chemicals (EDCs) have received widespread attention over the years due to their deleterious effects on human health. Bisphenol A (BPA) - a monomer used globally in producing polycarbonate plastics and epoxy resins, is a prototypic EDC that has received widespread attention due to its estrogenic activity. BPA has been detected in human serum, urine, amniotic fluid, placenta tissues, and umbilical cord blood. Its presence in the human population has been ascribed to consuming BPA-contaminated food due to its migration from polycarbonate plastics. However, little is known about the inimical health hazard of BPA migrating from polycarbonate bottles into food or drinks in Nigeria and how temperature and storage duration can influence its migration into any contact media. To address this problem, we scrutinized the effect of storage time and temperature on BPA migration from 3 selected polycarbonate water bottles and a brand of polycarbonate baby feeding bottles into ...