Modifications Incorporated in CpG Motifs of Oligodeoxynucleotides Lead to Antagonist Activity of Toll-like Receptors 7 and 9
Fugang Zhu
Journal of Medicinal Chemistry, 2009
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Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation
Paul J Payette
Immunology, 2004
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Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity
Klaus Heeg
Immunology, 2008
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Novel oligodeoxynucleotide agonists of TLR9 containing N3-Me-dC or N1-Me-dG modifications
Mallikarjuna Putta
2006
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Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent Toll-like receptor 9 agonists
jimmy tang
Proceedings of the National Academy of Sciences, 2005
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Oligodeoxyribonucleotide-Based Antagonists for Toll-Like Receptors 7 and 9
jimmy tang
Journal of Medicinal Chemistry, 2009
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Development of CpG-oligodeoxynucleotides for effective activation of rabbit TLR9 mediated immune responses
Ping-hui Tseng
PloS one, 2014
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Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity
Arthur Krieg
Journal of Leukocyte Biology, 2004
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Agonists of Toll-like Receptor 9 Containing Synthetic Dinucleotide Motifs
Mallikarjuna Putta
Journal of Medicinal Chemistry, 2007
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Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction
Atie Suwarti
Biochemical and biophysical research communications, 2013
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Synthesis and immunological activities of novel agonists of toll-like receptor 9
Ireneusz Nowak
Cellular Immunology, 2010
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Guanine-Modified Inhibitory Oligonucleotides Efficiently Impair TLR7- and TLR9-Mediated Immune Responses of Human Immune Cells
Hermann Wagner
PLOS ONE, 2015
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CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses
Chiou-Hwa Cathy Yuh
Scientific reports, 2017
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A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
jimmy tang
Proceedings of the National Academy of Sciences, 2003
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Recent advances in the development of immunostimulatory oligonucleotides
Eugen Uhlmann
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Non-CpG-Containing Antisense 2′-Methoxyethyl Oligonucleotides Activate a Proinflammatory Response Independent of Toll-Like Receptor 9 or Myeloid Differentiation Factor 88
Sebastien Burel
Journal of Pharmacology and Experimental Therapeutics, 2005
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Impact of Secondary Structure of Toll-Like Receptor 9 Agonists on Interferon Alpha Induction
Mallikarjuna Putta
Antimicrobial Agents and Chemotherapy, 2008
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Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivo
Mallikarjuna Putta
Organic & Biomolecular Chemistry, 2013
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Toll-like Receptor 7 Selective Synthetic Oligoribonucleotide Agonists: Synthesis and Structure−Activity Relationship Studies
Fugang Zhu
Journal of Medicinal Chemistry, 2009
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Ligand-induced conformational changes allosterically activate Toll-like receptor 9
anjali verma
Nature Immunology, 2007
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Oligodeoxynucleotides Modifiers and PolyT Imidazoquinoline Immune Response TLR8 by a Combination of Cutting Edge: Activation of Murine
John Vasilakos
2010
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Toll-Like Receptor 9-Independent Suppression of Skin Inflammation by Oligonucleotides
Andor Pivarcsi
Journal of Investigative Dermatology, 2007
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Activation of rabbit TLR9 by different CpG-ODN optimized for mouse and human TLR9
Jeng-fan Lo
Comparative Immunology, Microbiology and Infectious Diseases, 2012
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Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles
jimmy tang
Nucleic Acids Research, 2003
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Synthetic oligoribonucleotides containing arabinonucleotides act as agonists of TLR7 and 8
daqing wang
Bioorganic & Medicinal Chemistry Letters, 2009
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The Distinct and Cooperative Roles of Toll-Like Receptor 9 and Receptor for Advanced Glycation End Products in Modulating In Vivo Inflammatory Responses to Select CpG and Non-CpG Oligonucleotides
Suzanne Paz
Nucleic acid therapeutics, 2017
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Modulating Toll-like Receptor 7 and 9 Responses as Therapy for Allergy and Autoimmunity
Petar Lenert
Current Allergy and Asthma Reports, 2011
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High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9–TRIF pathway
Louis Boon
Nature Communications, 2013
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