Immunology Research Papers - Academia.edu (original) (raw)

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PENGAMATAN SEL DARAH MERAH, HEMOGLOBIN, HEMATOKRIT, SEL DARAH PUTIH, DIFERENSIAL LEUKOSIT, AKTIFITAS FAGOSITIK, RESPIRATORY BURST DAN LISOSIM PADA IKAN

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Komplemen merupakan salah satu molekul humoral dari imunitas innate/ non spesifik, walaupun perannya juga terlibat di imunitas spesifik. Komplemen membentuk suatu sistem yang disebut sistem komplemen merupakan salah satu sistem enzim yang diketahui terdapat lebih dari 30 molekul yang terlarut maupun yang terikat sel (Kindt et al., 2007).Komplemen beraksi sebagai sistem perondaan yang cepat dan efisien, sehingga dapat membedakan pengaruh sel host yang sehat dan sel host yang telah mengalami perubahan serta membedakan bahan asing yang menyusup ke dalam host (Ricklin et al., 2010).Reaksi yang ditimbulkan dari aktivasi komplemen berjalan berurutan (casacade) yang pada akhirnya mengaktivkan suatu komplemen terminal/ ujung (C5 – C9) yang mencetuskan/ trigger proses lisisnya membrane sel target (contoh : mikroba), proses ini disebut dengan Membrane Attack Complex (MAC).

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Immunology Research Papers - Academia.edu (original) (raw)

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