Riddelliine (original) (raw)
Riddelliine is a chemical compound classified as a pyrrolizidine alkaloid. It was first isolated from and is also found in a variety of plants including Jacobaea vulgaris, Senecio vulgaris, and others plants in the genus Senecio. Riddelliine can be found as a contaminant in foods such as meat, grains, seeds, milk, herbal tea, and honey. Riddelliine is suspected to be a carcinogen. It is listed as an IARC Group 2B carcinogen and listed by the National Toxicology Program in its Report on Carcinogens which lists chemicals "known or reasonably anticipated to cause cancer in humans".
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| dbo:abstract | Riddelliina es un compuesto químico clasificado como un . Fue aislado por primera vez de y también se encuentra en una variedad de plantas, incluyendo Jacobaea vulgaris, Senecio vulgaris, y otras plantas del género Senecio. Riddelliina se puede encontrar como contaminante en alimentos como la carne, granos, semillas, leche, té de hierbas y miel. Riddelliina se sospecha que es un agente cancerígeno. Está listado como un carcinógeno IARC Grupo 2B y catalogada por el , en su informe sobre carcinógenos que enumera los productos químicos "conocidos o probables por causar cáncer en los seres humanos". (es) Riddelliine is a chemical compound classified as a pyrrolizidine alkaloid. It was first isolated from and is also found in a variety of plants including Jacobaea vulgaris, Senecio vulgaris, and others plants in the genus Senecio. Riddelliine can be found as a contaminant in foods such as meat, grains, seeds, milk, herbal tea, and honey. Riddelliine is suspected to be a carcinogen. It is listed as an IARC Group 2B carcinogen and listed by the National Toxicology Program in its Report on Carcinogens which lists chemicals "known or reasonably anticipated to cause cancer in humans". (en) La riddelliina è un alcaloide del gruppo degli alcaloidi pirrolizidinici, isolato per la prima volta dalla pianta Senecio riddellii. È il diestere della retronecina con l'acido riddellico. La riddelliina può essere trovata come contaminante in alimenti come carne, cereali, semi, latte, tisane e miele. Si sospetta che la riddelliina sia cancerogena. È elencato come cancerogeno del Gruppo 2B dall'Agenzia internazionale per la ricerca sul cancro. La riddelliina è costituita da un diestere macrociclico di retronecina (un alcol insaturo) e (un acido bicarbossilico ossigenato, ramificato). La riddelliina è un solido cristallino da incolore a biancastro a temperatura ambiente. È solubile in cloroformio, acetone ed etanolo ed è scarsamente solubile in acqua. Come solido, è stabile a temperatura ambiente con luce diffusa per 12 mesi o più. Le soluzioni alcoliche e acquose di riddelliina sono stabili a temperatura ambiente se protette dalla luce. Emette fumi tossici di ossidi di azoto quando riscaldata fino alla decomposizione. (it) リデリイン（英: riddelliine）は、ピロリジジンアルカロイドに分類される化合物である。Senecio riddelliiから初めて単離され、、ノボロギク、その他のキオン属等の様々な植物でも見られる。 リデリインは、肉、穀物、種子、牛乳、ハーブティー、蜂蜜等の食物中にも夾雑物として含まれる。 リデリインは、発癌性物質であると疑われている。国際がん研究機関のIARC発がん性リスク一覧で、グループ2B（ヒトに対する発癌性が疑われる）に分類され、また米国国家毒性プログラムのReport on Carcinogensにも、ヒトにがんを引き起こすことが知られているまたは合理的に予測される物質として掲載されている。 (ja) |
| dbo:alternativeName | Riddelline; Riddelliine; Riddeline; Riddelliin (en) |
| dbo:iupacName | (15E)-12,18-Dihydroxy-13,19-didehydrosenecionan-11,16-dione (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Riddelliine.svg?width=300 |
| dbo:wikiPageExternalLink | http://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/symphytum-officinale.html https://www.ncbi.nlm.nih.gov/pubmed/3994126 |
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| dbp:imagefile | Riddelliine.svg (en) |
| dbp:imagesize | 180 (xsd:integer) |
| dbp:iupacname | -1218 (xsd:integer) |
| dbp:othernames | Riddelline; Riddelliine; Riddeline; Riddelliin (en) |
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| dcterms:subject | dbc:Alkene_derivatives dbc:Diols dbc:IARC_Group_2B_carcinogens dbc:Lactones dbc:Pyrrolizidine_alkaloids |
| gold:hypernym | dbr:Compound |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Abstraction100002137 yago:Alkaloid114712692 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:ChemicalCompound yago:Substance100019613 yago:WikicatPyrrolizidineAlkaloids |
| rdfs:comment | Riddelliine is a chemical compound classified as a pyrrolizidine alkaloid. It was first isolated from and is also found in a variety of plants including Jacobaea vulgaris, Senecio vulgaris, and others plants in the genus Senecio. Riddelliine can be found as a contaminant in foods such as meat, grains, seeds, milk, herbal tea, and honey. Riddelliine is suspected to be a carcinogen. It is listed as an IARC Group 2B carcinogen and listed by the National Toxicology Program in its Report on Carcinogens which lists chemicals "known or reasonably anticipated to cause cancer in humans". (en) リデリイン（英: riddelliine）は、ピロリジジンアルカロイドに分類される化合物である。Senecio riddelliiから初めて単離され、、ノボロギク、その他のキオン属等の様々な植物でも見られる。 リデリインは、肉、穀物、種子、牛乳、ハーブティー、蜂蜜等の食物中にも夾雑物として含まれる。 リデリインは、発癌性物質であると疑われている。国際がん研究機関のIARC発がん性リスク一覧で、グループ2B（ヒトに対する発癌性が疑われる）に分類され、また米国国家毒性プログラムのReport on Carcinogensにも、ヒトにがんを引き起こすことが知られているまたは合理的に予測される物質として掲載されている。 (ja) Riddelliina es un compuesto químico clasificado como un . Fue aislado por primera vez de y también se encuentra en una variedad de plantas, incluyendo Jacobaea vulgaris, Senecio vulgaris, y otras plantas del género Senecio. Riddelliina se puede encontrar como contaminante en alimentos como la carne, granos, semillas, leche, té de hierbas y miel. (es) La riddelliina è un alcaloide del gruppo degli alcaloidi pirrolizidinici, isolato per la prima volta dalla pianta Senecio riddellii. È il diestere della retronecina con l'acido riddellico. La riddelliina può essere trovata come contaminante in alimenti come carne, cereali, semi, latte, tisane e miele. Si sospetta che la riddelliina sia cancerogena. È elencato come cancerogeno del Gruppo 2B dall'Agenzia internazionale per la ricerca sul cancro. (it) |
| rdfs:label | Riddelliina (es) Riddelliina (it) リデリイン (ja) Riddelliine (en) |
| owl:differentFrom | dbr:Ritalin |
| owl:sameAs | freebase:Riddelliine yago-res:Riddelliine wikidata:Riddelliine dbpedia-es:Riddelliine dbpedia-fa:Riddelliine dbpedia-it:Riddelliine dbpedia-ja:Riddelliine dbpedia-sh:Riddelliine dbpedia-sr:Riddelliine https://global.dbpedia.org/id/3dWhz |
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| is dbo:wikiPageRedirects of | dbr:Riddeline dbr:Riddelliin dbr:Riddelline |
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