Microtubule nucleation at the centrosome and beyond (original) (raw)
De Forges, H., Bouissou, A. & Perez, F. Interplay between microtubule dynamics and intracellular organization. Int. J. Biochem. Cell Biol.44, 266–274 (2012). CASPubMed Google Scholar
Akhshi, T. K., Wernike, D. & Piekny, A. Microtubules and actin crosstalk in cell migration and division. Cytoskeleton71, 1–23 (2014). CASPubMed Google Scholar
Petry, S., Groen, A. C., Ishihara, K., Mitchison, T. J. & Vale, R. D. Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell152, 768–777 (2013). CASPubMedPubMed Central Google Scholar
Maiato, H., Rieder, C. L. & Khodjakov, A. Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis. J. Cell Biol.167, 831–840 (2004). CASPubMedPubMed Central Google Scholar
Heald, R. et al. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature382, 420–425 (1996). CASPubMed Google Scholar
Tassin, A. M., Maro, B. & Bornens, M. Fate of microtubule-organizing centers during myogenesis in vitro. J. Cell Biol.100, 35–46 (1985). CASPubMed Google Scholar
Chabin-Brion, K. et al. The Golgi complex is a microtubule-organizing organelle. Mol. Biol. Cell12, 2047–2060 (2001). CASPubMedPubMed Central Google Scholar
Efimov, A. et al. Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network. Dev. Cell12, 917–930 (2007). CASPubMedPubMed Central Google Scholar
Murata, T. et al. Microtubule-dependent microtubule nucleation based on recruitment of gamma-tubulin in higher plants. Nat. Cell Biol.7, 961–968 (2005). CASPubMed Google Scholar
Janson, M. E., Setty, T. G., Paoletti, A. & Tran, P. T. Efficient formation of bipolar microtubule bundles requires microtubule-bound γ-tubulin complexes. J. Cell Biol.169, 297–308 (2005). CASPubMedPubMed Central Google Scholar
Mogensen, M. M. & Tucker, J. B. Evidence for microtubule nucleation at plasma membrane-associated sites in Drosophila. J. Cell Sci.88, 95–107 (1987). PubMed Google Scholar
Moritz, M., Zheng, Y., Alberts, B. M. & Oegema, K. Recruitment of the γ-tubulin ring complex to Drosophila salt-stripped centrosome scaffolds. J. Cell Biol.142, 775–786 (1998). CASPubMedPubMed Central Google Scholar
Oegema, K. et al. Characterization of two related Drosophila γ-tubulin complexes that differ in their ability to nucleate microtubules. J. Cell Biol.144, 721–733 (1999). CASPubMedPubMed Central Google Scholar
Murphy, S. M. et al. GCP5 and GCP6: two new members of the human γ-tubulin complex. Mol. Biol. Cell12, 3340–3352 (2001). CASPubMedPubMed Central Google Scholar
Kollman, J. M., Merdes, A., Mourey, L. & Agard, D. A. Microtubule nucleation by γ-tubulin complexes. Nat. Rev. Mol. Cell Biol.12, 709–721 (2011). CASPubMedPubMed Central Google Scholar
Zheng, Y., Wong, M. L., Alberts, B. & Mitchison, T. Nucleation of microtubule assembly by a γ-tubulin-containing ring complex. Nature378, 578–583 (1995). CASPubMed Google Scholar
Kollman, J. M., Polka, J. K., Zelter, A., Davis, T. N. & Agard, D. A. Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry. Nature466, 879–882 (2010). CASPubMedPubMed Central Google Scholar
Keating, T. J. & Borisy, G. G. Immunostructural evidence for the template mechanism of microtubule nucleation. Nat. Cell Biol.2, 352–357 (2000). CASPubMed Google Scholar
Moritz, M., Braunfeld, M. B., Guenebaut, V., Heuser, J. & Agard, D. A. Structure of the γ-tubulin ring complex: a template for microtubule nucleation. Nat. Cell Biol.2, 365–370 (2000). CASPubMed Google Scholar
Wiese, C. & Zheng, Y. A new function for the γ-tubulin ring complex as a microtubule minus-end cap. Nat. Cell Biol.2, 358–364 (2000). CASPubMed Google Scholar
Guillet, V. et al. Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation. Nat. Struct. Mol. Biol.18, 915–919 (2011). CASPubMedPubMed Central Google Scholar
Kollman, J. M. et al. Ring closure activates yeast γTuRC for species-specific microtubule nucleation. Nat. Struct. Mol. Biol.22, 132–137 (2015). CASPubMedPubMed Central Google Scholar
Sawin, K. E., Lourenco, P. C. & Snaith, H. A. Microtubule nucleation at non-spindle pole body microtubule-organizing centers requires fission yeast centrosomin-related protein mod20p. Curr. Biol.14, 763–775 (2004). CASPubMed Google Scholar
Lin, T. C. et al. Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation. eLife3, e02208 (2014). PubMedPubMed Central Google Scholar
Lynch, E. M., Groocock, L. M., Borek, W. E. & Sawin, K. E. Activation of the γ-tubulin complex by the Mto1/2 complex. Curr. Biol.24, 896–903 (2014). CASPubMedPubMed Central Google Scholar
Liu, L. & Wiese, C. Xenopus NEDD1 is required for microtubule organization in Xenopus egg extracts. J. Cell Sci.121, 578–589 (2008). CASPubMed Google Scholar
Luders, J., Patel, U. K. & Stearns, T. GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nat. Cell Biol.8, 137–147 (2006). PubMed Google Scholar
Haren, L. et al. NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J. Cell Biol.172, 505–515 (2006). CASPubMedPubMed Central Google Scholar
Pinyol, R., Scrofani, J. & Vernos, I. The role of NEDD1 phosphorylation by Aurora A in chromosomal microtubule nucleation and spindle function. Curr. Biol.23, 143–149 (2013). CASPubMed Google Scholar
Sdelci, S. et al. Nek9 phosphorylation of NEDD1/GCP-WD contributes to Plk1 control of γ-tubulin recruitment to the mitotic centrosome. Curr. Biol.22, 1516–1523 (2012). CASPubMed Google Scholar
Hutchins, J. R. A. et al. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science328, 593–599 (2010). CASPubMedPubMed Central Google Scholar
Teixido-Travesa, N. et al. The γTuRC revisited: a comparative analysis of interphase and mitotic human γTuRC redefines the set of core components and identifies the novel subunit GCP8. Mol. Biol. Cell21, 3963–3972 (2010). CASPubMedPubMed Central Google Scholar
Zimmerman, W. C., Sillibourne, J., Rosa, J. & Doxsey, S. J. Mitosis-specific anchoring of γ tubulin complexes by pericentrin controls spindle organization and mitotic entry. Mol. Biol. Cell15, 3642–3657 (2004). CASPubMedPubMed Central Google Scholar
Takahashi, M., Yamagiwa, A., Nishimura, T., Mukai, H. & Ono, Y. Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring γ-tubulin ring complex. Mol. Biol. Cell13, 3235–3245 (2002). CASPubMedPubMed Central Google Scholar
Gillingham, A. K. & Munro, S. The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin. EMBO Rep.1, 524–529 (2000). CASPubMedPubMed Central Google Scholar
Zhu, H., Coppinger, J. A., Jang, C. Y., Yates, J. R., 3rd & Fang, G. FAM29A promotes microtubule amplification via recruitment of the NEDD1-γ-tubulin complex to the mitotic spindle. J. Cell Biol.183, 835–848 (2008). CASPubMedPubMed Central Google Scholar
Casenghi, M. et al. Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev. Cell5, 113–125 (2003). CASPubMed Google Scholar
Choi, Y. K., Liu, P., Sze, S. K., Dai, C. & Qi, R. Z. CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex. J. Cell Biol.191, 1089–1095 (2010). CASPubMedPubMed Central Google Scholar
Liu, P., Choi, Y. K. & Qi, R. Z. NME7 is a functional component of the γ-tubulin ring complex. Mol. Biol. Cell25, 2017–2025 (2014). PubMedPubMed Central Google Scholar
Bugnard, E., Zaal, K. J. & Ralston, E. Reorganization of microtubule nucleation during muscle differentiation. Cell Mot. Cytoskel.60, 1–13 (2005). Google Scholar
Fant, X., Srsen, V., Espigat-Georger, A. & Merdes, A. Nuclei of non-muscle cells bind centrosome proteins upon fusion with differentiating myoblasts. PLoS One4, e8303 (2009). PubMedPubMed Central Google Scholar
Batzenschlager, M. et al. The GIP γ-tubulin complex-associated proteins are involved in nuclear architecture in Arabidopsis thaliana. Front. Plant Sci.4, 480 (2013). PubMedPubMed Central Google Scholar
Seltzer, V. et al. Arabidopsis GCP2 and GCP3 are part of a soluble γ-tubulin complex and have nuclear envelope targeting domains. Plant J. Cell Mol. Biol.52, 322–331 (2007). CAS Google Scholar
Erhardt, M. et al. The plant Spc98p homologue colocalizes with γ-tubulin at microtubule nucleation sites and is required for microtubule nucleation. J. Cell Sci.115, 2423–2431 (2002). CASPubMed Google Scholar
Miller, P. M. et al. Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells. Nat. Cell Biol.11, 1069–1080 (2009). CASPubMedPubMed Central Google Scholar
Roubin, R. et al. Myomegalin is necessary for the formation of centrosomal and Golgi-derived microtubules. Biol. Open2, 238–250 (2013). CASPubMed Google Scholar
Rivero, S., Cardenas, J., Bornens, M. & Rios, R. M. Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130. EMBO J.28, 1016–1028 (2009). CASPubMedPubMed Central Google Scholar
Wang, Z. et al. Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J. Biol. Chem.285, 22658–22665 (2010). CASPubMedPubMed Central Google Scholar
Gruss, O. J. & Vernos, I. The mechanism of spindle assembly: functions of Ran and its target TPX2. J. Cell Biol.166, 949–955 (2004). CASPubMedPubMed Central Google Scholar
Clarke, P. R. & Zhang, C. Spatial and temporal coordination of mitosis by Ran GTPase. Nat. Rev. Mol. Cell Biol.9, 464–477 (2008). CASPubMed Google Scholar
Maresca, T. J. et al. Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity. Curr. Biol.19, 1210–1215 (2009). CASPubMedPubMed Central Google Scholar
Mishra, R. K., Chakraborty, P., Arnaoutov, A., Fontoura, B. M. & Dasso, M. The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores. Nat. Cell Biol.12, 164–169 (2010). CASPubMedPubMed Central Google Scholar
Tulu, U. S., Fagerstrom, C., Ferenz, N. P. & Wadsworth, P. Molecular requirements for kinetochore-associated microtubule formation in mammalian cells. Curr. Biol.16, 536–541 (2006). CASPubMedPubMed Central Google Scholar
Chan, J., Sambade, A., Calder, G. & Lloyd, C. Arabidopsis cortical microtubules are initiated along, as well as branching from, existing microtubules. Plant Cell21, 2298–2306 (2009). CASPubMedPubMed Central Google Scholar
Mahoney, N. M., Goshima, G., Douglass, A. D. & Vale, R. D. Making microtubules and mitotic spindles in cells without functional centrosomes. Curr. Biol.16, 564–569 (2006). CASPubMed Google Scholar
Brugues, J., Nuzzo, V., Mazur, E. & Needleman, D. J. Nucleation and transport organize microtubules in metaphase spindles. Cell149, 554–564 (2012). CASPubMed Google Scholar
Goshima, G. et al. Genes required for mitotic spindle assembly in Drosophila S2 cells. Science316, 417–421 (2007). CASPubMedPubMed Central Google Scholar
Goshima, G., Mayer, M., Zhang, N., Stuurman, N. & Vale, R. D. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J. Cell Biol.181, 421–429 (2008). CASPubMedPubMed Central Google Scholar
Uehara, R. et al. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc. Natl Acad. Sci. USA106, 6998–7003 (2009). CASPubMedPubMed Central Google Scholar
Lawo, S. et al. HAUS, the 8subunit human Augmin complex, regulates centrosome and spindle integrity. Curr. Biol.19, 816–826 (2009). CASPubMed Google Scholar
Hsia, K. C. et al. Reconstitution of the augmin complex provides insights into its architecture and function. Nat. Cell Biol.16, 852–863 (2014). CASPubMedPubMed Central Google Scholar
Ho, C. M. et al. Augmin plays a critical role in organizing the spindle and phragmoplast microtubule arrays in Arabidopsis. Plant Cell23, 2606–2618 (2011). CASPubMed Google Scholar
Hotta, T. et al. Characterization of the Arabidopsis augmin complex uncovers its critical function in the assembly of the acentrosomal spindle and phragmoplast microtubule arrays. Plant Cell24, 1494–1509 (2012). CASPubMedPubMed Central Google Scholar
Nakaoka, Y. et al. An inducible RNA interference system in Physcomitrella patens reveals a dominant role of augmin in phragmoplast microtubule generation. Plant Cell24, 1478–1493 (2012). CASPubMedPubMed Central Google Scholar
Liu, T. et al. Augmin triggers microtubule-dependent microtubule nucleation in interphase plant cells. Curr. Biol.24, 2708–2713 (2014). CASPubMed Google Scholar
Machesky, L. M., Atkinson, S. J., Ampe, C., Vandekerckhove, J. & Pollard, T. D. Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. J. Cell Biol.127, 107–115 (1994). CASPubMed Google Scholar
Firat-Karalar, E. N. & Welch, M. D. New mechanisms and functions of actin nucleation. Curr. Opin. Cell Biol.23, 4–13 (2011). CASPubMed Google Scholar
Srayko, M., Kaya, A., Stamford, J. & Hyman, A. A. Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo. Dev. Cell9, 223–236 (2005). CASPubMed Google Scholar
Rogers, G. C., Rusan, N. M., Peifer, M. & Rogers, S. L. A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells. Mol. Biol. Cell19, 3163–3178 (2008). CASPubMedPubMed Central Google Scholar
Groen, A. C., Maresca, T. J., Gatlin, J. C., Salmon, E. D. & Mitchison, T. J. Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly. Mol. Biol. Cell20, 2766–2773 (2009). CASPubMedPubMed Central Google Scholar
Popov, A. V., Severin, F. & Karsenti, E. XMAP215 is required for the microtubule-nucleating activity of centrosomes. Curr. Biol.12, 1326–1330 (2002). CASPubMed Google Scholar
Wieczorek, M., Bechstedt, S., Chaaban, S. & Brouhard, G. J. Microtubule-associated proteins control the kinetics of microtubule nucleation. Nat. Cell Biol.17, 907–916 (2015). CASPubMed Google Scholar
Roll-Mecak, A. & Vale, R. D. Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays? J. Cell Biol.175, 849–851 (2006). CASPubMedPubMed Central Google Scholar