The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling (original) (raw)
Lodish, H.F., Zhou, B., Liu, G. & Chen, C.Z. Micromanagement of the immune system by microRNAs. Nat. Rev. Immunol.8, 120–130 (2008). ArticleCASPubMed Google Scholar
Lewis, B.P., Burge, C.B. & Bartel, D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell120, 15–20 (2005). ArticleCASPubMed Google Scholar
Miranda, K.C. et al. A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. Cell126, 1203–1217 (2006). ArticleCASPubMed Google Scholar
Friedman, R.C., Farh, K.K., Burge, C.B. & Bartel, D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res.19, 92–105 (2009). ArticleCASPubMedPubMed Central Google Scholar
Lee, Y., Jeon, K., Lee, J.T., Kim, S. & Kim, V.N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J.21, 4663–4670 (2002). ArticleCASPubMedPubMed Central Google Scholar
Liu, J. et al. Argonaute2 is the catalytic engine of mammalian RNAi. Science305, 1437–1441 (2004). ArticleCASPubMed Google Scholar
Lund, E., Guttinger, S., Calado, A., Dahlberg, J.E. & Kutay, U. Nuclear export of microRNA precursors. Science303, 95–98 (2004). ArticleCASPubMed Google Scholar
Zhang, N. & Bevan, M.J. Dicer controls CD8+ T-cell activation, migration, and survival. Proc. Natl. Acad. Sci. USA107, 21629–21634 (2010). ArticleCASPubMedPubMed Central Google Scholar
Clurman, B.E. & Hayward, W.S. Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. Mol. Cell Biol.9, 2657–2664 (1989). CASPubMedPubMed Central Google Scholar
Thai, T.H. et al. Regulation of the germinal center response by microRNA-155. Science316, 604–608 (2007). ArticleCASPubMed Google Scholar
Costinean, S. et al. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc. Natl. Acad. Sci. USA103, 7024–7029 (2006). ArticleCASPubMedPubMed Central Google Scholar
Tili, E. et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-α stimulation and their possible roles in regulating the response to endotoxin shock. J. Immunol.179, 5082–5089 (2007). ArticleCASPubMed Google Scholar
O'Connell, R.M. et al. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity33, 607–619 (2010). ArticleCASPubMedPubMed Central Google Scholar
Kohlhaas, S. et al. Cutting edge: The Foxp3 target miR-155 contributes to the development of regulatory T cells. J. Immunol.182, 2578–2582 (2009). ArticleCASPubMed Google Scholar
Lu, L.F. et al. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity30, 80–91 (2009). ArticleCASPubMedPubMed Central Google Scholar
Tsai, C.Y., Allie, S.R., Zhang, W. & Usherwood, E.J. MicroRNA miR-155 affects antiviral effector and effector memory CD8 T cell differentiation. J. Virol.87, 2348–2351 (2013). ArticleCASPubMedPubMed Central Google Scholar
Lind, E.F., Elford, A.R. & Ohashi, P.S. Micro-RNA 155 Is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges. J. Immunol.190, 1210–1216 (2013). ArticleCASPubMed Google Scholar
Kolumam, G.A., Thomas, S., Thompson, L.J., Sprent, J. & Murali-Krishna, K. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med.202, 637–650 (2005). ArticleCASPubMedPubMed Central Google Scholar
Curtsinger, J.M. et al. IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation. J. Immunol.174, 4465–4469 (2005). ArticleCASPubMed Google Scholar
Gil, M.P., Salomon, R., Louten, J. & Biron, C.A. Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo. Blood107, 987–993 (2006). ArticleCASPubMedPubMed Central Google Scholar
Marshall, H.D., Urban, S.L. & Welsh, R.M. Virus-induced transient immune suppression and the inhibition of T cell proliferation by type I interferon. J. Virol.85, 5929–5939 (2011). ArticleCASPubMedPubMed Central Google Scholar
McNally, J.M. et al. Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses. J. Virol.75, 5965–5976 (2001). ArticleCASPubMedPubMed Central Google Scholar
Ebert, P.J., Jiang, S., Xie, J., Li, Q.J. & Davis, M.M. An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat. Immunol.10, 1162–1169 (2009). ArticleCASPubMedPubMed Central Google Scholar
Li, Q.J. et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell129, 147–161 (2007). ArticleCASPubMed Google Scholar
Agarwal, P. et al. Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory. J. Immunol.183, 1695–1704 (2009). ArticleCASPubMed Google Scholar
Sana, T.R., Janatpour, M.J., Sathe, M., McEvoy, L.M. & McClanahan, T.K. Microarray analysis of primary endothelial cells challenged with different inflammatory and immune cytokines. Cytokine29, 256–269 (2005). CASPubMed Google Scholar
Tsuchihashi, S., Zhai, Y., Fondevila, C., Busuttil, R.W. & Kupiec-Weglinski, J.W. HO-1 upregulation suppresses type 1 IFN pathway in hepatic ischemia/reperfusion injury. Transplant. Proc.37, 1677–1678 (2005). ArticleCASPubMed Google Scholar
Kashiwada, M. et al. Downstream of tyrosine kinases-1 and Src homology 2-containing inositol 5′-phosphatase are required for regulation of CD4+CD25+ T cell development. J. Immunol.176, 3958–3965 (2006). ArticleCASPubMed Google Scholar
O'Connell, R.M., Chaudhuri, A.A., Rao, D.S. & Baltimore, D. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc. Natl. Acad. Sci. USA106, 7113–7118 (2009). ArticleCASPubMedPubMed Central Google Scholar
Cocolakis, E. et al. Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation. J. Biol. Chem.283, 1293–1307 (2008). ArticleCASPubMed Google Scholar
Erickson, S. et al. Interferon-α inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes. Eur. J. Biochem.269, 29–37 (2002). ArticleCASPubMed Google Scholar
Haasch, D. et al. T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC. Cell Immunol.217, 78–86 (2002). ArticleCASPubMed Google Scholar
Dondi, E., Rogge, L., Lutfalla, G., Uze, G. & Pellegrini, S. Down-modulation of responses to type I IFN upon T cell activation. J. Immunol.170, 749–756 (2003). ArticleCASPubMed Google Scholar
Erickson, S. et al. Interferon-α inhibits proliferation in human T lymphocytes by abrogation of interleukin 2-induced changes in cell cycle-regulatory proteins. Cell Growth Differ.10, 575–582 (1999). CASPubMed Google Scholar
Gimeno, R., Lee, C.K., Schindler, C. & Levy, D.E. Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by α/β interferon in T lymphocytes. Mol. Cell Biol.25, 5456–5465 (2005). ArticleCASPubMedPubMed Central Google Scholar
Tanabe, Y. et al. Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-αβ responses in T lymphocytes. J. Immunol.174, 609–613 (2005). ArticleCASPubMed Google Scholar
Linsley, P.S. et al. Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol. Cell Biol.27, 2240–2252 (2007). ArticleCASPubMedPubMed Central Google Scholar
Tsang, J., Zhu, J. & van Oudenaarden, A. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol. Cell26, 753–767 (2007). ArticleCASPubMedPubMed Central Google Scholar
Wherry, E.J. et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol.4, 225–234 (2003). ArticleCASPubMed Google Scholar
Usherwood, E.J. et al. Immunological control of murine gammaherpesvirus infection is independent of perforin. J. Gen. Virol.78, 2025–2030 (1997). ArticleCASPubMed Google Scholar
Borowski, A.B. et al. Memory CD8+ T cells require CD28 costimulation. J. Immunol.179, 6494–6503 (2007). ArticleCASPubMed Google Scholar
Dolfi, D.V. et al. Dendritic cells and CD28 costimulation are required to sustain virus-specific CD8+ T cell responses during the effector phase in vivo. J. Immunol.186, 4599–4608 (2011). ArticleCASPubMed Google Scholar
Shen, L., Evel-Kabler, K., Strube, R. & Chen, S.Y. Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity. Nat. Biotechnol.22, 1546–1553 (2004). ArticleCASPubMed Google Scholar
Abate, A., Zhao, H., Wong, R.J. & Stevenson, D.K. The role of Bach1 in the induction of heme oxygenase by tin mesoporphyrin. Biochem. Biophys. Res. Commun.354, 757–763 (2007). ArticleCASPubMedPubMed Central Google Scholar
Lu, Y. et al. Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic. J. Biol. Chem.281, 36683–36690 (2006). ArticleCASPubMed Google Scholar
Lin, R., Mamane, Y. & Hiscott, J. Multiple regulatory domains control IRF-7 activity in response to virus infection. J. Biol. Chem.275, 34320–34327 (2000). ArticleCASPubMed Google Scholar
Tusher, V.G., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA98, 5116–5121 (2001). ArticleCASPubMedPubMed Central Google Scholar
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA102, 15545–15550 (2005). ArticleCASPubMedPubMed Central Google Scholar