Augmentation of the migratory ability of DC-based vaccine into regional lymph nodes by efficient CCR7 gene transduction (original) (raw)

• Nestle FO et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 1998; 4: 328–332.
  Article CAS PubMed Google Scholar
• Thurner B et al. Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med 1999; 190: 1669–1678.
  Article CAS PubMed PubMed Central Google Scholar
• Lodge PA et al. Dendritic cell-based immunotherapy of prostate cancer: immune monitoring of a phase II clinical trial. Cancer Res 2000; 60: 829–833.
  CAS PubMed Google Scholar
• Yu JS et al. Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration. Cancer Res 2001; 61: 842–847.
  CAS PubMed Google Scholar
• Banchereau J, Steinman RM . Dendritic cells and the control of immunity. Nature 1998; 392: 245–252.
  Article CAS PubMed Google Scholar
• Steinman RM et al. Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. Hum Immunol 1999; 60: 562–567.
  Article CAS PubMed Google Scholar
• Mellman I, Steinman RM . Dendritic cells: specialized and regulated antigen processing machines. Cell 2001; 106: 255–258.
  Article CAS PubMed Google Scholar
• Gunn MD et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med 1999; 189: 451–460.
  Article CAS PubMed PubMed Central Google Scholar
• Förster R et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999; 99: 23–33.
  Article PubMed Google Scholar
• Arthur JF et al. A comparison of gene transfer methods in human dendritic cells. Cancer Gene Ther 1997; 4: 17–25.
  CAS PubMed Google Scholar
• Okada N et al. Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors. Biochem Biophys Res Commun 2001; 282: 173–179.
  Article CAS PubMed Google Scholar
• Okada N et al. Efficient antigen gene transduction using Arg–Gly–Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells. Cancer Res 2001; 61: 7913–7919.
  CAS PubMed Google Scholar
• Okada N et al. Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors. Cancer Gene Ther 2003; 10: 421–431.
  Article CAS PubMed Google Scholar
• Okada N et al. Dendritic cells transduced with gp100 gene by RGD fiber-mutant adenovirus vectors are highly efficacious in generating anti-B16BL6 melanoma immunity in mice. Gene Therapy 2003; 10: 1891–1902.
  Article CAS PubMed Google Scholar
• Lanzavecchia A . Identifying strategies for immune intervention. Science 1993; 260: 937–944.
  Article CAS PubMed Google Scholar
• Lappin MB et al. Analysis of mouse dendritic cell migration in vivo upon subcutaneous and intravenous injection. Immunology 1999; 98: 181–188.
  Article CAS PubMed PubMed Central Google Scholar
• Martín-Fontecha A et al. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med 2003; 198: 615–621.
  Article PubMed PubMed Central Google Scholar
• Kleindienst P, Brocker T . Endogenous dendritic cells are required for amplification of T cell responses induced by dendritic cell vaccines in vivo. J Immunol 2003; 170: 2817–2823.
  Article CAS PubMed Google Scholar
• Granucci F et al. Early events in dendritic cell maturation induced by LPS. Microbes Infect 1999; 1: 1079–1084.
  Article CAS PubMed Google Scholar
• Dhodapkar MV et al. Antigen-specific inhibition of effector T cell function in human after injection of immature dendritic cells. J Exp Med 2001; 193: 233–238.
  Article CAS PubMed PubMed Central Google Scholar
• Steinman RM, Nussenzweig MC . Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci USA 2002; 99: 351–358.
  Article CAS PubMed PubMed Central Google Scholar
• Steinbrink K et al. CD4+ and CD8+ anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 2002; 99: 2468–2476.
  Article CAS PubMed Google Scholar
• Mahnke K et al. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002; 80: 477–483.
  Article PubMed Google Scholar
• Huang FP et al. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med 2000; 191: 435–444.
  Article CAS PubMed PubMed Central Google Scholar
• Hemmi H et al. Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-β1-dependent cells. Int Immunol 2001; 13: 695–704.
  Article CAS PubMed Google Scholar
• Yanagawa Y, Onoe K . CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities. Blood 2003; 101: 4923–4929.
  Article CAS PubMed Google Scholar
• Saeki H, Moore AM, Brown MJ, Hwang ST . Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J Immunol 1999; 162: 2472–2475.
  CAS PubMed Google Scholar
• Curiel-Lewandrowski C et al. Transfection of immature murine bone marrow-derived dendritic cells with the granulocyte-macropharge colony-stimulating factor gene potently enhances their in vivo antigen-presenting capacity. J Immunol 1999; 163: 174–183.
  CAS PubMed Google Scholar
• Hirao M et al. CC chemokine receptor-7 on dendritic cell is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes. Cancer Res 2000; 60: 2209–2217.
  CAS PubMed Google Scholar
• Wu MT, Hwang ST . CXCR5-transduced bone marrow-derived dendritic cells traffic to B cell zones of lymph nodes and modify antigen-specific immune responses. J Immunol 2002; 168: 5096–5102.
  Article CAS PubMed Google Scholar
• Nakamura M et al. Dendritic cells genetically engineered to simultaneously express endogenous tumor antigen and granulocyte macrophage colony-stimulating factor elicit potent therapeutic antitumor immunity. Clin Cancer Res 2002; 8: 2742–2749.
  CAS PubMed Google Scholar
• de Vries IJM et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res 2003; 63: 12–17.
  CAS PubMed Google Scholar
• Eggert AAO et al. Analysis of dendritic cell trafficking using EGFP-transgenic mice. Immunol Lett 2003; 89: 17–24.
  Article CAS PubMed Google Scholar
• Scandella E et al. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 2002; 100: 1354–1361.
  Article CAS PubMed Google Scholar
• Scandella E et al. CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2. Blood 2004; 103: 1595–1601.
  Article CAS PubMed Google Scholar
• Sato M et al. Generation of mature dendritic cells fully capable of T helper type 1 polarization using OK-432 combined with prostaglandin E2 . Cancer Sci 2003; 94: 1091–1098.
  Article CAS PubMed Google Scholar
• Nair S et al. Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J Immunol 2003; 171: 6275–6282.
  Article CAS PubMed Google Scholar
• Pfeifer JD et al. Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature 1993; 361: 359–362.
  Article CAS PubMed Google Scholar
• Okabe M et al. Green mice as a source of ubiquitous green cells. FEBS Lett 1997; 407: 313–319.
  Article CAS PubMed Google Scholar
• Mizuguchi H et al. A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob. Gene Therapy 2001; 8: 730–735.
  Article CAS PubMed Google Scholar
• Mizuguchi H, Kay MA . Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. Hum Gene Ther 1998; 9: 2577–2583.
  Article CAS PubMed Google Scholar
• Mizuguchi H, Kay MA . A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors. Hum Gene Ther 1999; 10: 2013–2017.
  Article CAS PubMed Google Scholar
• Lutz MB et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 1999; 223: 77–92.
  Article CAS PubMed Google Scholar
• Okada N et al. Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens. Br J Cancer 2001; 84: 1564–1570.
  Article CAS PubMed PubMed Central Google Scholar