Engineered polyketide biosynthesis and biocatalysis in Escherichia coli
AB Rifa'i
Applied Microbiology and Biotechnology, 2010
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Steps towards the synthetic biology of polyketide biosynthesis
Rainer Breitling
2014
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Preparative production of an enantiomeric pair by engineered polyketide synthases
Tristan Clay
Chemical Communications, 2021
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Heterologous Production of Epothilone C and D in Escherichia coli
Jonathan Kennedy
Biochemistry, 2006
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Synthetic Polyketide Enzymology: Platform for Biosynthesis of Antimicrobial Polyketides
Jantana Wongsantichon
ACS Catalysis, 2015
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Modular Construction of a Functional Artificial Epothilone Polyketide Pathway
HUbert Bernauer
ACS Synthetic Biology, 2012
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Heterologous production of polyketides by modular type I polyketide synthases in Escherichia coli
Jay D Keasling
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Construction of a Part of a 3‑Hydroxypropionate Cycle for Heterologous Polyketide Biosynthesis in Escherichia coli
Jay D Keasling
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An artificial pathway for polyketide biosynthesis
Lindsay Nichols
Nature Catalysis, 2020
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Narrowing the gap between the promise and reality of polyketide synthases as a synthetic biology platform
Jay D Keasling
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Engineering of a minimal modular polyketide synthase, and targeted alteration of the stereospecificity of polyketide chain extension
Jesús Mateo Cortés
Chemistry & Biology, 1998
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Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes
Hugo Menzella
Nature Biotechnology, 2005
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Synthetic biology enabling access to designer polyketides
Lindsay Nichols
Current Opinion in Chemical Biology, 2020
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Minimally Invasive Mutagenesis Gives Rise to a Biosynthetic Polyketide Library
Andreas Brockmeyer
Angewandte Chemie International Edition, 2012
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A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis
steven van lanen
Proceedings of the National Academy of Sciences, 2008
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Engineering polyketide synthases and nonribosomal peptide synthetases
Gavin P Williams
Current Opinion in Structural Biology, 2013
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Technical Advances to Accelerate Modular Type I Polyketide Synthase Engineering towards a Retro-biosynthetic Platform
Yao Wan
Biotechnology and Bioprocess Engineering, 2019
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Polyketide synthesis in vitro on a modular polyketide synthase
Jesús Mateo Cortés
Chemistry & Biology, 1995
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Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity
Xiaoying Bian
Microbial Cell Factories
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New insights into bacterial type II polyketide biosynthesis
zhuan zhang
F1000Research, 2017
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A comprehensive and engaging overview of the type III family of polyketide synthases
Alex Praseuth
Current Opinion in Chemical Biology, 2007
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Chemoinformatic-guided engineering of polyketide synthases
Edward Baidoo
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Rational Design and Assembly of Synthetic Trimodular Polyketide Synthases
Hugo Menzella
Chemistry & Biology, 2007
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Recombinatorial biosynthesis of polyketides
Antonio Starcevic
Journal of Industrial Microbiology & Biotechnology, 2011
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The Assembly Line Enzymology of Polyketide Biosynthesis
Paul Race
Methods in molecular biology (Clifton, N.J.), 2016
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Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase
Peter Leadlay
Chemistry & Biology, 2001
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New Start and Finish for Complex Polyketide Biosynthesis
Patrick Caffrey
Chemistry & Biology, 2004
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Dissecting complex polyketide biosynthesis
Patrick Caffrey
Computational and structural biotechnology journal, 2012
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Enhancing the Atom Economy of Polyketide Biosynthetic Processes through Metabolic Engineering
Timothy Leaf
Biotechnology Progress, 2001
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Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites
Douglas Gatte Picchi
Proceedings of the National Academy of Sciences of the United States of America, 2011
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Crystal Structure of a Bacterial Type III Polyketide Synthase and Enzymatic Control of Reactive Polyketide Intermediates
Joseph Noel
Journal of Biological Chemistry, 2004
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A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ' mix and match ' E. coli expression system with microscale experimentation
Leonardo Rios
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Escherichia coli Allows Efficient Modular Incorporation of Newly Isolated Quinomycin Biosynthetic Enzyme into Echinomycin Biosynthetic Pathway for Rational Design and Synthesis of Potent Antibiotic Unnatural Natural Product
Kinya Hotta
Journal of The American Chemical Society, 2009
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Reprogramming the Biosynthesis of Natural Products by Directed Evolution
Gavin P Williams
ACS Symposium Series, 2013
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Engineered Biosynthesis of a Novel Amidated Polyketide, Using the Malonamyl-Specific Initiation Module from the Oxytetracycline Polyketide Synthase
Wenjun Zhang
Applied and Environmental Microbiology, 2006
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