Steps towards the synthetic biology of polyketide biosynthesis (original) (raw)
Synthetic Polyketide Enzymology: Platform for Biosynthesis of Antimicrobial Polyketides
Jantana Wongsantichon
ACS Catalysis, 2015
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Narrowing the gap between the promise and reality of polyketide synthases as a synthetic biology platform
Jay D Keasling
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Synthetic biology enabling access to designer polyketides
Lindsay Nichols
Current Opinion in Chemical Biology, 2020
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An artificial pathway for polyketide biosynthesis
Lindsay Nichols
Nature Catalysis, 2020
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Using Chemobiosynthesis and Synthetic Mini-Polyketide Synthases To Produce Pharmaceutical Intermediates in Escherichia coli
Hugo Menzella
Applied and Environmental Microbiology, 2010
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Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes
Hugo Menzella
Nature Biotechnology, 2005
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A comprehensive and engaging overview of the type III family of polyketide synthases
Alex Praseuth
Current Opinion in Chemical Biology, 2007
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Minimally Invasive Mutagenesis Gives Rise to a Biosynthetic Polyketide Library
Andreas Brockmeyer
Angewandte Chemie International Edition, 2012
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Polyketide synthesis in vitro on a modular polyketide synthase
Jesús Mateo Cortés
Chemistry & Biology, 1995
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Recombinatorial biosynthesis of polyketides
Antonio Starcevic
Journal of Industrial Microbiology & Biotechnology, 2011
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Chemoinformatic-guided engineering of polyketide synthases
Edward Baidoo
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The Assembly Line Enzymology of Polyketide Biosynthesis
Paul Race
Methods in molecular biology (Clifton, N.J.), 2016
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New insights into bacterial type II polyketide biosynthesis
zhuan zhang
F1000Research, 2017
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Engineering polyketide synthases and nonribosomal peptide synthetases
Gavin P Williams
Current Opinion in Structural Biology, 2013
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Engineering of a minimal modular polyketide synthase, and targeted alteration of the stereospecificity of polyketide chain extension
Jesús Mateo Cortés
Chemistry & Biology, 1998
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Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products
Arinthip Thamchaipenet
Proceedings of the National Academy of Sciences, 1999
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Engineered polyketide biosynthesis and biocatalysis in Escherichia coli
AB Rifa'i
Applied Microbiology and Biotechnology, 2010
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ASMPKS: an analysis system for modular polyketide synthases
Kiejung Park
BMC Bioinformatics, 2007
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Technical Advances to Accelerate Modular Type I Polyketide Synthase Engineering towards a Retro-biosynthetic Platform
Yao Wan
Biotechnology and Bioprocess Engineering, 2019
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Dissecting complex polyketide biosynthesis
Patrick Caffrey
Computational and structural biotechnology journal, 2012
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Rational Design of Macrolides by Virtual Screening of Combinatorial Libraries Generated through in Silico Manipulation of Polyketide Synthases
Vladimir Poroikov
Journal of Medicinal Chemistry, 2006
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Comparative Characterization of the Lactimidomycin and iso-Migrastatin Biosynthetic Machineries Revealing Unusual Features for Acyltransferase-less Type I Polyketide Synthases and Providing an Opportunity To Engineer New Analogues
Chris Farnet
Biochemistry, 2014
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Combinatorial biosynthesis for drug development
Hugo Menzella
Current Opinion in Microbiology, 2007
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Mechanistic insights into the biosynthesis of polyketide antibiotics
Azmiri Sultana
2006
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Heterologous production of polyketides by modular type I polyketide synthases in Escherichia coli
Jay D Keasling
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Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase
Peter Leadlay
Chemistry & Biology, 2001
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Bioinspired iterative synthesis of polyketides
Changmin Xie
Frontiers in Chemistry, 2015
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Rational Design and Assembly of Synthetic Trimodular Polyketide Synthases
Hugo Menzella
Chemistry & Biology, 2007
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Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites
Douglas Gatte Picchi
Proceedings of the National Academy of Sciences of the United States of America, 2011
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Preparative production of an enantiomeric pair by engineered polyketide synthases
Tristan Clay
Chemical Communications, 2021
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New Start and Finish for Complex Polyketide Biosynthesis
Patrick Caffrey
Chemistry & Biology, 2004
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Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
István Molnár
Proceedings of the National Academy of Sciences of the United States of America, 2014
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Metabolic Engineering of Type III PKS for Over Production of Secondary Metabolites in Heterologous Host System
Momena Khandaker
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Enhancing the Atom Economy of Polyketide Biosynthetic Processes through Metabolic Engineering
Timothy Leaf
Biotechnology Progress, 2001
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Diversity of Polyketide Synthases Found in the Aspergillus and Streptomyces Genomes
Yi-ming Chiang
Molecular Pharmaceutics, 2008
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