p75-Ras-GRF1 Is a c-Jun/AP-1 Target Protein: Its Up Regulation Results in Increased Ras Activity and Is Necessary for c-Jun-Induced Nonadherent Growth of Rat1a Cells (original) (raw)

Ras-Dependent Regulation of c-Jun Phosphorylation Is Mediated by the Ral Guanine Nucleotide Exchange Factor-Ral Pathway

Rob Wolthuis

Molecular and Cellular Biology, 2000

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Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases

Masahiko Hibi

Proceedings of the National Academy of Sciences, 1994

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Signal transduction in fibroblasts stably transformed by [Val12]Ras--the activities of extracellular-signal-regulated kinase and Jun N-terminal kinase are only moderately increased, and the activity of the delta-inhibitor of c-Jun is not alleviated

Maria Shoshan

European journal of biochemistry / FEBS, 1997

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Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase

Matthew Pincus

Annals of clinical and laboratory science, 2000

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Increased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activation

Mary Cutler

Molecular and cellular biology, 1996

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Ras-dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKC delta

Shigeo Ohno

The EMBO Journal, 1994

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Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts

Tom Kerppola

1992

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Transformation by ras modifies AP1 composition and activity

Fatima Mechta-Grigoriou

Oncogene, 1997

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M-Ras/R-Ras3, a Transforming Ras Protein Regulated by Sos1, GRF1, and p120 Ras GTPase-activating Protein, Interacts with the Putative Ras Effector AF6

Lawrence Quilliam

Journal of Biological Chemistry, 1999

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An Effector Peptide from Glutathione-S-Transferase-pi Strongly and Selectively Blocks Mitotic Signaling by Oncogenic ras-p21

Fred Friedman

The Protein Journal, 2000

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The defective transforming phenotype of c-Jun Ala63/73 is rescued by mutation of the C-terminal phosphorylation site

Irene Marchetti

Oncogene, 2001

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Signal Transduction in Fibroblasts Stably Transformed by [Val12]Ras

K. Sollerbrant

European Journal of Biochemistry, 1997

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Multiple signal transduction pathways mediate c-Jun protein phosphorylation

Tino Unlap

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1993

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Positive autoregulation of ras genes expression in fibroblasts

T. Thomson

FEBS Letters, 1997

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Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation

Michèle Garlatti, Linh-chi Bui, Xavier Coumoul

Biochemical Pharmacology, 2011

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Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

Jonathan Chernoff

1997

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Requirement of c-Jun NH2-Terminal Kinase for Ras-Initiated Tumor Formation

Peter Sandy

Molecular and Cellular Biology, 2011

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Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

E. Valo, Jukka Westermarck, M. Jäättelä

Oncogene, 2012

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Francois Claret

Cell, 1995

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Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes

Maria Castellone

Oncogene, 2003

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Nuclear Factor of Activated T3 Is a Negative Regulator of Ras-JNK1/2-AP-1–Induced Cell Transformation

Yong Yeon Cho

Cancer Research, 2007

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Specific Biochemical Inactivation of Oncogenic Ras Proteins by Nucleoside Diphosphate Kinase1

NDK 13

2003

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Role of protein kinase C in ras-mediated fos-expression

Hans Grunicke

Advances in Enzyme Regulation, 1994

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Ras signalling and apoptosis

Julian Downward

Current Opinion in Genetics & Development, 1998

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jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

Jean Viallet

Cell, 1989

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Raf-independent Deregulation of p38 and JNK Mitogen-activated Protein Kinases Are Critical for Ras Transformation

Kevin Pruitt

Journal of Biological Chemistry, 2002

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Cell Signaling: Life or Death Decisions of Ras Proteins

Rachel Buchsbaum

Current Biology, 2002

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Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation

Jody Haigh

Nature Cell Biology, 2010

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Heterodimerization with Fra-1 cooperates with the ERK pathway to stabilize c-Jun in response to the RAS oncoprotein

F. Talotta, Laura Casalino

Oncogene, 2010

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Disruption of c-Jun Reduces Cellular Migration and Invasion through Inhibition of c-Src and Hyperactivation of ROCK II Kinase

Kongming Wu, Richard Pestell

Molecular Biology of the Cell, 2008

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