The Rac1/p38 Mitogen-activated Protein Kinase Pathway Is Required for Interferon α-dependent Transcriptional Activation but Not Serine Phosphorylation of Stat Proteins
Dr. M. Shahab Uddin
Journal of Biological Chemistry, 2000
View PDFchevron_right
Identification of STAT2 Serine 287 as a Novel Regulatory Phosphorylation Site in Type I Interferon-induced Cellular Responses
Ana Gamero, C. Barrero
Journal of Biological Chemistry, 2013
View PDFchevron_right
Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons
Thomas Decker
EMBO reports, 2003
View PDFchevron_right
Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages
Ilkka Julkunen
Journal of Immunology, 1997
View PDFchevron_right
Cells Previously Desensitized to Type 1 Interferons Display Different Mechanisms of Activation of Stat-dependent Gene Expression from Naive Cells
Ana Gamero
Journal of Biological Chemistry, 2003
View PDFchevron_right
The Proximal Tyrosines of the Cytoplasmic Domain of the beta Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation. EVIDENCE THAT TWO Stat2 SITES ARE REQUIRED TO REACH A THRESHOLD OF INTERFERON alpha -INDUCED Stat2 TYROSINE ...
Regina Raz
Journal of Biological Chemistry, 1999
View PDFchevron_right
The WD Motif-containing Protein Receptor for Activated Protein Kinase C (RACK1) Is Required for Recruitment and Activation of Signal Transducer and Activator of Transcription 1 through the Type I Interferon Receptor
Gleb Baida
Journal of Biological Chemistry, 2001
View PDFchevron_right
The Proximal Tyrosines of the Cytoplasmic Domain of the β Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation
Regina Raz
Journal of Biological Chemistry, 1999
View PDFchevron_right
STAT2 Binding to the Interferon-α Receptor 2 Subunit is Not Required for Interferon-α Signaling
Abu Saleh
Journal of Biological …, 2002
View PDFchevron_right
Stat2 Binding to the Interferon-alpha Receptor 2 Subunit Is Not Required for Interferon-alpha Signaling
abu saleh
Journal of Biological Chemistry, 2002
View PDFchevron_right
The Stat1 Binding Motif of the Interferon-gamma Receptor Is Sufficient to Mediate Stat5 Activation and Its Repression by SOCS3
Thomas Decker
Journal of Biological Chemistry, 2001
View PDFchevron_right
Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1
Paul Hertzog
PLoS Biology, 2010
View PDFchevron_right
Activation of a CrkL-Stat5 Signaling Complex by Type I Interferons
Shahab Uddin
Journal of Biological Chemistry, 1999
View PDFchevron_right
CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response
Lars Dölken
Immunity, 2013
View PDFchevron_right
Activation of Protein Kinase C by IFN-
Arshad Rahman
The Journal of Immunology, 2003
View PDFchevron_right
Interferon-Dependent Activation of the Serine Kinase PI 3′-Kinase Requires Engagement of the IRS Pathway but Not the Stat Pathway
shahab uddin
Biochemical and Biophysical Research Communications, 2000
View PDFchevron_right
Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses
Thomas Decker
Frontiers in immunology, 2017
View PDFchevron_right
Activation of Different Stat5 Isoforms Contributes to Cell-Type- Restricted Signaling in Response to Interferons
Andreas L Meinke
1996
View PDFchevron_right
Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway
Thomas Decker
1999
View PDFchevron_right
Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-γ, but not IFN-α, signaling
Mitsuharu Sato
Embo Journal, 1999
View PDFchevron_right
p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation
Thomas Decker
Proceedings of the National Academy of Sciences, 2002
View PDFchevron_right
Interferon-α activates signal transducers and activators of transcription 5 and 6 in Daudi cells
Elizaveta Fasler-kan
1998
View PDFchevron_right
Activation of STAT transcription factors in oncogenic tyrosine kinase signaling
Roy Garcia
Journal of Biomedical Science, 1998
View PDFchevron_right
JAK-STAT Signaling: From Interferons to Cytokines
David Levy
Journal of Biological Chemistry, 2007
View PDFchevron_right
Interferon-alpha activates signal transducers and activators of transcription 5 and 6 in Daudi cells
Elizaveta Fasler-kan
European Journal of Biochemistry, 1998
View PDFchevron_right
Inhibitor of κB kinase is required to activate a subset of interferon γ-stimulated genes
Sandhya Rani
2004
View PDFchevron_right
Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR
Thomas Decker
The Journal of biological chemistry, 2001
View PDFchevron_right
I B kinase (IKK ) regulates the balance between type I and type II interferon responses
B. Tenoever
Proceedings of the National Academy of Sciences, 2011
View PDFchevron_right