Achillea millefolium Research Papers - Academia.edu (original) (raw)

Bracon hebetor say bee is one of the most important biological control factors that can be effective in controlling larvae of lepidoptera pests such as Helicoverpa armigera hubner at acceptable economic level. The present review was aimed... more

Bracon hebetor say bee is one of the most important biological control factors that can be effective in controlling larvae of lepidoptera pests such as Helicoverpa armigera hubner at acceptable economic level. The present review was aimed at studying probable adverse effects of Achillea millefolium, Lavandula angustifolia, and Mentha piperita plants extracts on adult insect of the B. hebetor bee. The bee was grown on last instar larvae of Ephestia kueheniella Zell. All bioassay experiments were carried out at temperature of 26±1°C and relative humidity of 60±5, and under photoperiod conditions of 16 hours of lightness and 8 hours of darkness. Findings of the study indicated that spearmint plant had the highest lethal effect on adult insect of B. hebetor bee in fumigant and contact toxicities and other plants, respectively, Achillea millefolium, Lavandula angustifolia, and Mentha piperita had the least lethal effect on adult insect of B. hebetor bee in fumigant and contact toxicities. The estimated LC50 value for spearmint plant at 48 hours was 6 microliters/ml in fumigant toxicity and 3.2 microliter/ml in contact toxicity. Repellency effect of spearmint, Achillea millefolium, Lavandula angustifolia, and Mentha piperita plants extracts was studied on adult insect using tube -Y olfactory-meter device. Cotton wool soaked with the extract was placed at one end of the device and the other end was closed with web and the insects were released in the main branch. Each iteration of the experiment was conducted on 20 insects. Results of analysis of variance (ANOVA) of the data related to repellency effect of the studied extracts indicated that being a stronger repellant compared to other two extracts, spearmint extract with lower concentration can repel adult insects of B. hebetor bee.

Based on the traditional folk use, the anti-diarrheal activity of the methanolic extract of Achillea millefolium L. (AM) leaves was evaluated on castor oil-induced diarrhoea and assessment of gastrointestinal propulsion of charcoal meal... more

Based on the traditional folk use, the anti-diarrheal activity of the methanolic extract of Achillea millefolium L.
(AM) leaves was evaluated on castor oil-induced diarrhoea and assessment of gastrointestinal propulsion of
charcoal meal in rats. Achillea millefolium L. commonly known as yarrow belonging to the family Asteraceae, is an
ancient traditional herb native to Europe and is used to treat wounds, hepatic disorders, gastrointestinal disorders,
spasmodic diseases, headaches, pain, inflammation and diarrhoea. The three doeses of Achillea millefolium L.
methanolic extract has been selected (150 mg/kg, 300 mg/kg and 450 mg/kg). Among three dosages of AM leaves,
the two dosages (300 mg/kg-IIIb and 450 mg/kg IIIc) showed a significant reduction in various parameters like
distance travelled (IIIb-25±1.679 cm; IIIc-17±2.534 cm) and % average travelled (IIIb-47.16; IIIc-32.69) travelled
in charcoal meal model when compaired to control group. Phytochemical screening of the plant extract revealed the
presence of flavonoids, tannins, steroids and terpenes. Results showed that the methanolic extract of Achillea
millefolium Leaves possess anti-diarrhoeal activity possibly mediated by inhibiting the intestinal motility,
hydroelectrolyte secretion and by making intestinal mucosa more resistant to chemical alteration and hence reduce
secretions.

Breast cancer is the second main cause of death among women. The use of medicinal plants has been common in many countries since ancient times. The aim of this study was to evaluate the antioxidant and anti-proliferative potential of... more

Breast cancer is the second main cause of death among women. The use of medicinal plants has been common in many countries since ancient times. The aim of this study was to evaluate the antioxidant and anti-proliferative potential of Achillea millefolium L. The antioxidant activity of the aqueous and hydroalcoholic extracts of Achillea millefolium L. leaf and flower was measured by DPPH and FRAP method while its anti-proliferative activity on MCF-7 human breast cancer cell line was evaluated using MTT assay. The ethanolic extract of the leaf and the methanolic extract of the flower had the highest radical scavenging and ferric ion reducing activities. Time and dose-dependent cytotoxic effects of different extracts were observed on MCF-7 cells. The difference in cell viability between hydroalcholic (methanol and ethanol) and aqueous extracts of leaf and flower was significant (P< 0.05), but there was no significant difference in cell viability between methanolic and ethanolic extracts of leaf (P< 0.05). IC50 values varied between 7 and 93 μg/ ml with ethanolic extracts being more cytotoxic and flower extract exhibiting a higher antiproliferative effect than leaf extract. The presence of antioxidant activity as well as high cytotoxic effect of all examined extracts suggest that Achillea millefolium may possess a potential chemotherapeutic activity for breast cancer treatment.

Plant based drugs have been in used against various diseases since time immemorial. In India the indigenous system of medicine namely Unani, Ayurveda & Siddha have been in existence for several centuries. This article bridges the gap... more

Plant based drugs have been in used against various diseases since time immemorial. In India the indigenous system of medicine namely Unani, Ayurveda & Siddha have been in existence for several centuries. This article bridges the gap between the traditional use of brinjasif (Achillea millefolium Linn) and the results of evidence based experiments. It is a flowering plant of the family Asteraceae and is widely used in Unani system of medicine as muhallile warm (anti-inflammatory) musakine dard (analgesic), dafia’h huma (antipyretic), mudire boul (diuretic), mudire haiz (emmenogogue), qatil kirme shikam (antihelmentic). Studies have shown that it possess anti-inflammatory, anti-oxidant, antimicrobial, analgesic, anti-spasmodic, hepatoprotective, gastro-protective activities.