Liver Disease Research Papers - Academia.edu (original) (raw)
- by arun e
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- Clinical Trial, Inflammation, Hepatology, Humans
Liver fibrosis has evolved in the past 20 years from a pure laboratory discipline to an area of great bedside relevance to practicing hepatologists. This evolution reflects growing awarenessnotonlyofthemolecularunderpinni..., but also of... more
Liver fibrosis has evolved in the past 20 years from a pure laboratory discipline to an area of great bedside relevance to practicing hepatologists. This evolution reflects growing awarenessnotonlyofthemolecularunderpinni..., but also of its natural history and methods of detection in chronic liver disease. These ...
Fatty liver (FL) is the most frequent liver disease in Western countries. We used data from the Dionysos Nutrition & Liver Study to develop a simple algorithm for the prediction of FL in the general population. 216 subjects with and 280... more
Fatty liver (FL) is the most frequent liver disease in Western countries. We used data from the Dionysos Nutrition & Liver Study to develop a simple algorithm for the prediction of FL in the general population. 216 subjects with and 280 without suspected liver disease were studied. FL was diagnosed by ultrasonography and alcohol intake was assessed using a 7-day diary. Bootstrapped stepwise logistic regression was used to identify potential predictors of FL among 13 variables of interest [gender, age, ethanol intake, alanine transaminase, aspartate transaminase, gamma-glutamyl-transferase (GGT), body mass index (BMI), waist circumference, sum of 4 skinfolds, glucose, insulin, triglycerides, and cholesterol]. Potential predictors were entered into stepwise logistic regression models with the aim of obtaining the most simple and accurate algorithm for the prediction of FL. An algorithm based on BMI, waist circumference, triglycerides and GGT had an accuracy of 0.84 (95%CI 0.81-0.87) i...
- by I. Theodorou
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- Genetics, Gastroenterology, Biopsy, Humans
- by Vijay Puri and +1
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- Treatment, Cardiovascular disease, Platelet, Prospective studies
- by Steffen Christensen and +1
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- Electronic Health Records, Adolescent, Comorbidity, Denmark
- by Ezio David and +1
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- Anthropometry, Hepatology, Metabolic syndrome, Insulin Resistance
Class III multidrug resistance (MDR) P-glycoproteins (P-gp), mdr2 in mice and MDR3 in man, mediate the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Mice with a disrupted mdr2 gene completely lack... more
Class III multidrug resistance (MDR) P-glycoproteins (P-gp), mdr2 in mice and MDR3 in man, mediate the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Mice with a disrupted mdr2 gene completely lack biliary ...