Male Mice Research Papers - Academia.edu (original) (raw)

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The present study is designed to investigate the effect of 2mg/ml/day of flutamide on the melanocortin -5-recepter (MC5R); total lipid compounds; essential pheromone compounds and histological structure of the preputial gland of intact... more

The present study is designed to investigate the effect of 2mg/ml/day of flutamide on the melanocortin -5-recepter (MC5R);
total lipid compounds; essential pheromone compounds and histological structure of the preputial gland of intact male mice
after 42 days of treatment. Such treatment is resulted in a significant increase (P<0.01) of MC5R level as compared with the
control group. Moreover the total lipid contents did not alter from that of the control, but most of the essential pheromones compounds
are disappeared. The histological structure of the gland is atrophied and many acini are degenerated with a concomitant
increased of necrosis regions in the stroma of the gland.

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