Death Domain database (original) (raw)
The Death Domain database is a secondary database of protein-protein interactions (PPI) of the death domain superfamily. Members of this superfamily are key players in apoptosis, inflammation, necrosis, and immune cell signaling pathways. Negative death domain superfamily-mediated signaling events result in various human diseases which include, cancers, neurodegenerative diseases, and immunological disorders. Creating death domain databases are of particular interest to researchers in the biomedical field as it enables a further understanding of the molecular mechanisms involved in death domain interactions while also providing easy access to tools such as an interaction map that illustrates the protein-protein interaction network and information. There is currently only one database that
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dbo:abstract | The Death Domain database is a secondary database of protein-protein interactions (PPI) of the death domain superfamily. Members of this superfamily are key players in apoptosis, inflammation, necrosis, and immune cell signaling pathways. Negative death domain superfamily-mediated signaling events result in various human diseases which include, cancers, neurodegenerative diseases, and immunological disorders. Creating death domain databases are of particular interest to researchers in the biomedical field as it enables a further understanding of the molecular mechanisms involved in death domain interactions while also providing easy access to tools such as an interaction map that illustrates the protein-protein interaction network and information. There is currently only one database that exclusively looks at death domains but there are other databases and resources that have information on this superfamily. According to PubMed, this database has been cited by seven peer-reviewed articles to date because of its extensive and specific information on the death domains and their PPI summaries. (en) |
dbo:title | Death Domain Database (en) |
dbo:wikiPageExternalLink | http://www.deathdomain.org http://arquivo.pt/wayback/20160515224643/http:/www.deathbase.org/ |
dbo:wikiPageID | 34525276 (xsd:integer) |
dbo:wikiPageLength | 20652 (xsd:nonNegativeInteger) |
dbo:wikiPageRevisionID | 1047556332 (xsd:integer) |
dbo:wikiPageWikiLink | dbr:Cancers dbr:PubMed dbr:Publications dbr:Pyrin_domain dbr:Death_domain dbr:Death_effector_domain dbr:UniProt dbr:Inflammation dbr:Mutations dbr:Animal dbr:Apoptosis dbr:Mammals dbr:Chordata dbr:Statistics dbr:STRING dbr:Amino_acid dbc:Biological_databases dbr:Fasta_format dbr:KEGG dbr:Direct_Income_Payments dbc:Protein_domains dbr:Hyperlink dbr:Echinodermata dbr:Necrosis dbr:Caspase dbr:Genbank dbr:Species dbr:Simple_Modular_Architecture_Research_Tool dbr:Virus dbr:Nematoda dbr:Neurodegenerative_disease dbr:Diseases dbr:Phylum dbr:Nomenclature dbr:Uniprot dbr:Vertebrates dbr:Entrez_Gene dbr:Protein-protein_interactions dbr:Caspase_recruitment_domain dbr:Swiss-Prot dbr:Alpha-helices dbr:NF-kappaB dbr:Sequences |
dbp:author | Dongseop Kwon (en) |
dbp:description | protein-protein interaction database for the Death Domain superfamily. (en) |
dbp:pmid | Kwon & al. (en) |
dbp:released | 2011 (xsd:integer) |
dbp:title | Death Domain Database (en) |
dbp:url | http://www.deathdomain.org |
dbp:wikiPageUsesTemplate | dbt:Infobox_biodatabase dbt:Multiple_issues dbt:Orphan dbt:Reflist dbt:Third-party dbt:Manual |
dc:description | protein-protein interaction database for theDeath Domainsuperfamily. |
dct:subject | dbc:Biological_databases dbc:Protein_domains |
rdf:type | owl:Thing schema:CreativeWork dbo:Work wikidata:Q386724 dbo:Database dul:InformationObject dbo:BiologicalDatabase yago:Abstraction100002137 yago:Attribute100024264 yago:Environment113934596 yago:Situation113927383 yago:Sphere114514039 yago:State100024720 yago:WikicatProteinDomains |
rdfs:comment | The Death Domain database is a secondary database of protein-protein interactions (PPI) of the death domain superfamily. Members of this superfamily are key players in apoptosis, inflammation, necrosis, and immune cell signaling pathways. Negative death domain superfamily-mediated signaling events result in various human diseases which include, cancers, neurodegenerative diseases, and immunological disorders. Creating death domain databases are of particular interest to researchers in the biomedical field as it enables a further understanding of the molecular mechanisms involved in death domain interactions while also providing easy access to tools such as an interaction map that illustrates the protein-protein interaction network and information. There is currently only one database that (en) |
rdfs:label | Death Domain database (en) |
owl:sameAs | freebase:Death Domain database yago-res:Death Domain database wikidata:Death Domain database https://global.dbpedia.org/id/4j3RY |
prov:wasDerivedFrom | wikipedia-en:Death_Domain_database?oldid=1047556332&ns=0 |
foaf:homepage | http://www.deathdomain.org |
foaf:isPrimaryTopicOf | wikipedia-en:Death_Domain_database |
is dbo:wikiPageWikiLink of | dbr:Death_domain dbr:Biological_database |
is foaf:primaryTopic of | wikipedia-en:Death_Domain_database |