In molecular biology, a riboregulator is a ribonucleic acid (RNA) that responds to a signal nucleic acid molecule by Watson-Crick base pairing. A riboregulator may respond to a signal molecule in any number of manners including, translation (or repression of translation) of the RNA into a protein, activation of a ribozyme, release of silencing RNA (siRNA), conformational change, and/or binding other nucleic acids.Riboregulators contain two canonical domains, a sensor domain and an effector domain. These domains are also found on riboswitches, but unlike riboswitches, the sensor domain only binds complementary RNA or DNA strands as opposed to small molecules. Because binding is based on base-pairing, a riboregulator can be tailored to differentiate and respond to individual genetic sequence
Property |
Value |
dbo:abstract |
In molecular biology, a riboregulator is a ribonucleic acid (RNA) that responds to a signal nucleic acid molecule by Watson-Crick base pairing. A riboregulator may respond to a signal molecule in any number of manners including, translation (or repression of translation) of the RNA into a protein, activation of a ribozyme, release of silencing RNA (siRNA), conformational change, and/or binding other nucleic acids.Riboregulators contain two canonical domains, a sensor domain and an effector domain. These domains are also found on riboswitches, but unlike riboswitches, the sensor domain only binds complementary RNA or DNA strands as opposed to small molecules. Because binding is based on base-pairing, a riboregulator can be tailored to differentiate and respond to individual genetic sequences and combinations thereof. (en) |
dbo:thumbnail |
wiki-commons:Special:FilePath/Antisense_riboregulator.jpg?width=300 |
dbo:wikiPageExternalLink |
https://www.uniprot.org/uniprot/P42601 |
dbo:wikiPageID |
26069817 (xsd:integer) |
dbo:wikiPageLength |
10733 (xsd:nonNegativeInteger) |
dbo:wikiPageRevisionID |
1104501487 (xsd:integer) |
dbo:wikiPageWikiLink |
dbr:Prokaryotes dbr:Prokaryotic dbr:Breast_cancer dbr:Aptamer dbr:Arithmetic_operations dbr:Riboswitch dbr:Ribozyme dbr:DNA dbr:Nucleic_acid dbr:Gene_expression dbr:NOR_gate dbr:OR_gate dbr:Small_molecule dbr:Monocytes dbr:Kozak_consensus_sequence dbr:Synthetic_biology dbc:Non-coding_RNA dbr:HIV dbr:Alkaline dbc:Cis-regulatory_RNA_elements dbr:E._coli dbr:Eukaryotes dbr:Eukaryotic dbr:PH dbr:Protein dbr:RNA dbc:RNA dbr:International_Genetically_Engineered_Machine dbr:Stem-loop dbr:AND_gate dbr:Translation_(biology) dbr:Start_codon dbr:Marilyn_Kozak dbr:Antisense dbr:RNA_polymerase dbr:Shine-Dalgarno_sequence dbr:If-then-else dbr:Ribosome dbr:Molecular_biology dbr:Personalized_medicine dbr:Ribosome_binding_site dbr:Riboswitches dbr:5′_UTR dbr:60S dbr:Boolean_logic dbr:Watson-Crick_base_pair dbr:Secondary_structure dbr:Gene_regulatory_networks dbr:40S dbr:SiRNA dbr:Negated_AND_gate dbr:File:Antisense_riboregulator.jpg dbr:File:Stemloop_Riboregulator.jpg |
dbp:wikiPageUsesTemplate |
dbt:Cite_journal dbt:Cleanup_bare_URLs dbt:Refbegin dbt:Refend dbt:Reflist |
dcterms:subject |
dbc:Non-coding_RNA dbc:Cis-regulatory_RNA_elements dbc:RNA |
gold:hypernym |
dbr:Acid |
rdf:type |
yago:WikicatCis-regulatoryRNAElements yago:Abstraction100002137 yago:Cognition100023271 yago:Component105868954 yago:Concept105835747 yago:Content105809192 yago:Idea105833840 yago:Part105867413 yago:PsychologicalFeature100023100 dbo:ChemicalCompound |
rdfs:comment |
In molecular biology, a riboregulator is a ribonucleic acid (RNA) that responds to a signal nucleic acid molecule by Watson-Crick base pairing. A riboregulator may respond to a signal molecule in any number of manners including, translation (or repression of translation) of the RNA into a protein, activation of a ribozyme, release of silencing RNA (siRNA), conformational change, and/or binding other nucleic acids.Riboregulators contain two canonical domains, a sensor domain and an effector domain. These domains are also found on riboswitches, but unlike riboswitches, the sensor domain only binds complementary RNA or DNA strands as opposed to small molecules. Because binding is based on base-pairing, a riboregulator can be tailored to differentiate and respond to individual genetic sequence (en) |
rdfs:label |
Riboregulator (en) |
owl:sameAs |
freebase:Riboregulator yago-res:Riboregulator wikidata:Riboregulator https://global.dbpedia.org/id/4tuAv |
prov:wasDerivedFrom |
wikipedia-en:Riboregulator?oldid=1104501487&ns=0 |
foaf:depiction |
wiki-commons:Special:FilePath/Antisense_riboregulator.jpg wiki-commons:Special:FilePath/Stemloop_Riboregulator.jpg |
foaf:isPrimaryTopicOf |
wikipedia-en:Riboregulator |
is dbo:wikiPageWikiLink of |
dbr:Registry_of_Standard_Biological_Parts dbr:H19_(gene) dbr:James_Collins_(bioengineer) |
is gold:hypernym of |
dbr:RcsR1_small_RNA |
is foaf:primaryTopic of |
wikipedia-en:Riboregulator |