The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs
VITOR SERRÃO
PloS one, 2018
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Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis
Humberto Pereira
Journal of Molecular Biology, 2005
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Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Causal Agent of Schistosomiasis
Humberto Pereira
J Mol Biol, 2005
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Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor
Humberto Pereira
Acta Tropica, 2010
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Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate
Humberto Pereira
Journal of Synchrotron Radiation, 2011
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Cloning, expression and preliminary crystallographic studies of the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni
Humberto Pereira
Acta Crystallographica Section D Biological Crystallography, 2003
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Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: Kinetic and structural studies
Humberto Pereira
Bioorganic & Medicinal Chemistry, 2010
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Descriptor-and fragment-based QSAR models for a series of Schistosoma mansoni purine nucleoside inhibitors
Humberto Freitas
Journal of the Brazilian Chemical Society, 2011
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Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni
Humberto Pereira
Acta Crystallographica Section D Biological Crystallography, 2010
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Computational Design of Novel Candidate Drug Molecules for Schistosomiasis
daniel kariuki
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Homology modeling and docking studies of phosphoenolpyruvate carboxykinase in Schistosoma mansoni
Ananta Swargiary
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Crystal Structures of a Schistosomal Drug and Vaccine Target: Glutathione S-Transferase from Schistosoma japonica and its Complex with the Leading Antischistosomal Drug Praziquantel
John Tainer
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Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function
Antonio Marinho, Larissa Romanello
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Structural Comparative Analysis of Secreted NTPDase Models of Schistosoma mansoni and Homo sapiens
Vinicius A Souza
Advances in Bioinformatics and Computational Biology, 2014
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Discovery of novel Schistosoma mansoni PDE4A inhibitors as potential agents against schistosomiasis
Carmen Albores Gil
Future Medicinal Chemistry, 2019
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Structural basis for the design of selective inhibitors for Schistosoma mansoni dihydroorotate dehydrogenase
Felipe Antunes Calil
Biochimie, 2019
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Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors
Giuliana Papoff
Journal of Biological Chemistry
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Structural and Enzymatic Insights into Species-specific Resistance to Schistosome Parasite Drug Therapy
Chiara Polcaro
The Journal of biological chemistry, 2017
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In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni
José Clecildo Barreto Bezerra
PLoS Neglected Tropical Diseases, 2015
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Crystal Structures of a Schistosomal Drug and Vaccine Target: Glutathione S-Transferase fromSchistosoma japonicaand its Complex with the Leading Antischistomal Drug Praziquantel
Michele McTigue
Journal of Molecular Biology, 1995
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In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets
José Clecildo Barreto Bezerra
PLOS ONE, 2018
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Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex
Jorge Huete
Biochemistry, 1997
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Adenosine kinase from Schistosoma mansoni : structural basis for the differential incorporation of nucleoside analogues
Larissa Romanello, Ricardo Demarco, Fernando Bachega
Acta Crystallographica Section D Biological Crystallography, 2013
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Journal of Biomolecular Structure and Dynamics In-silico analysis of Sirt2 from Schistosoma mansoni: structures, conformations, and interactions with inhibitors In-silico analysis of Sirt2 from Schistosoma mansoni: structures, conformations, and interactions with inhibitors
swadha singh
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Phosphatidylinositol—and related-kinases: A genome-wide survey of classes and subtypes in the Schistosoma mansoni genome for designing subtype-specific inhibitors
Diana Bahia
Biochemical and Biophysical Research Communications, 2009
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Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni
Jindrich Fanfrlik
Journal of Biological Chemistry, 2011
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In-silico screening of Schistosoma mansoni Sirtuin1 inhibitors for prioritization of drug candidates
Birendra Yadav
SpringerPlus, 2016
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