Phototherapy Research Papers - Academia.edu (original) (raw)

OBJECTIVE: Decreased conjugation is probably more important than hemolysis for causing jaundice in G6PD-deficient neonates. The role of enzyme inducers, like phenobarbital, in G6PD deficiency is unclear. This randomized controlled trial... more

OBJECTIVE: Decreased conjugation is probably more important than hemolysis for causing jaundice in G6PD-deficient neonates. The role of enzyme inducers, like phenobarbital, in G6PD deficiency is unclear. This randomized controlled trial was performed to evaluate ...

Seasonal affective disorder (SAD) is characterized by recurrent episodes of major depression with a seasonal pattern, treated with light therapy (LT). Duration of light therapy differs. This study investigates retrospectively whether a... more

Seasonal affective disorder (SAD) is characterized by recurrent episodes of major depression with a seasonal pattern, treated with light therapy (LT). Duration of light therapy differs. This study investigates retrospectively whether a single week of LT is as effective as two weeks, whether males and females respond differently, and whether there is an effect of expectations as assessed before treatment. 83 women, and 25 men received either one-week (n=42) or two weeks (n=66) of LT were included in three studies. Before LT, patients׳ expectations on therapy response were assessed. Depression severity was similar in both groups before treatment (F(1,106)=0.19ns) and decreased significantly during treatment (main effect "time" F(2,105)=176.7, p<0.001). The speed of therapy response differs significantly in treatment duration, in favor of 1 week (F(2,105)=3.2, p=0.046). A significant positive correlation between expectations and therapy response was found in women (ρ=0.243...

O presente trabalho tem como objetivo explorar os conceitos de Ego e Self e o papel destes diferentes aspectos da psique humana para o desenvolvimento do ser em seu potencial. Dentro da complexidade de cada universo particular humano e... more

O presente trabalho tem como objetivo explorar os conceitos de Ego e Self e o papel destes diferentes aspectos da psique humana para o desenvolvimento do ser em seu potencial.
Dentro da complexidade de cada universo particular humano e dos contextos externos cada vez mais turbulentos e acelerados da contemporaneidade, nos parece essencial que a compreensão dos aspectos de nossa identidade e de nossa autenticidade seja aprofundada, permitindo mais espaços de diálogos internos que culminem no autodesenvolvimento e na plenitude da existência humana.
O texto a seguir irá expor as perspectivas de diferentes autores sobre os conceitos de Ego e de Self, propondo reflexões sobre o conceito de “eu”, o papel e a possível ausência do Ego, o saudável e necessário diálogo entre Ego e Self, as experiências culminantes como expressão do Self e a visão da Psicologia Transpessoal sobre os aspectos da psique.
Este estudo não se propõe a exaurir as possíveis visões sobre estes conceitos, mas sim facilitar o conhecimento de perspectivas já postas na história da psicologia e contribuir para a exploração da relação integradora e saudável entre estes dois aspectos, um consciente (Ego) e o outro superior (Self) do universo humano.
Esperamos que, ao ampliar a compreensão sobre si mesmo, cada ser possa garantir e atentar para os espaços de diálogo e escuta internos, viabilizando a expressão autêntica e única de seu potencial.

Phototherapy is the treatment indicated for the management of neonatal jaundice. There are different technologies to provide this treatment, including LED devices. For this study, a LED phototherapy lamp is developed to be used in... more

Phototherapy is the treatment indicated for the management of neonatal jaundice. There are different technologies to provide this treatment, including LED devices. For this study, a LED phototherapy lamp is developed to be used in neonatal jaundice. Its efficacy is compared with other devices by measuring the speed in reducing bilirubin levels. This lamp is built with an LED light source composed of a 15×25 LED array that generates 460nm. This device is characterized by being a very compact source of low energy consumption, long duration, and low cost. The obtained results are comparable with industrial manufacturing devices, but less expensive, therefore, more efficient in terms of health costs.

To comparatively and prospectively compare in a randomized clinical trial, dentin hypersensitivity after treatment with three in-office bleaching systems, based on hydrogen peroxide at different concentrations, with and without light... more

To comparatively and prospectively compare in a randomized clinical trial, dentin hypersensitivity after treatment with three in-office bleaching systems, based on hydrogen peroxide at different concentrations, with and without light source activation. 88 individuals were included according to inclusion and exclusion criteria. Subjects were randomly divided into the following three treatment groups: Group 1 was treated with three 15-minute applications of hydrogen peroxide at 15% with titanium dioxide (Lase Peroxide Lite) that was light-activated (Light Plus Whitening Lase) with five cycles of 1 minute and 30 seconds each cycle, giving a total treatment time of 45 minutes; Group 2 was treated with three 10-minute applications of hydrogen peroxide at 35% (Lase Peroxide Sensy), activated by light (LPWL) same activation cycles than Group 1, with a total treatment time of 30 minutes; Group 3 was treated with only one application for 45 minutes of hydrogen peroxide at 35% (Whitegold Offi...

The Life Album project. Alzheimer and image has been developed within the framework of Visiona (Image Program of Huesca) and in collaboration with the Alzheimer Association of Huesca. It is a pilot experience carried out to promote from... more

The Life Album project. Alzheimer and image has been developed within the framework of
Visiona (Image Program of Huesca) and in collaboration with the Alzheimer Association of Huesca.
It is a pilot experience carried out to promote from cultural practices, quality of life improvement of
patients and caregivers of Alzheimer’s and other dementias, with the photographic image as the engine
of cognitive and emotional processes. Specifically, from the promotion that a creative view can facilitate
thanks to the social and exploratory utilities of the photographic image. Thus, the project explores ways
based on photography that promote discovery, mobilization and dialogue between people affected by
the disease, with special interest in the relationship between patients and caregivers.

Rhesus haemolytic disease of the newborn can lead to complications such as hyperbilirubinaemia, kernicterus and anaemia. Postnatal management consists mainly of intensive phototherapy, exchange transfusion and blood transfusion. During... more

Rhesus haemolytic disease of the newborn can lead to complications such as hyperbilirubinaemia, kernicterus and anaemia. Postnatal management consists mainly of intensive phototherapy, exchange transfusion and blood transfusion. During the last decades, significant progress in prenatal care strategies for patients with Rhesus haemolytic disease has occurred. New prenatal management options have led to a remarkable reduction in perinatal mortality. As a result of the increase in perinatal survival, attention is now shifting towards short-term and long-term morbidity. This review focuses on the management of neonatal and paediatric complications associated with Rhesus haemolytic disease, discusses postnatal treatment options and summarizes the results of studies on short-term and long-term outcome.

The aim of this study was to analyze the effect of laser or light-emitting diode (LED) phototherapy on the bone formation at the midpalatal suture after rapid maxilla expansion. Twenty young adult male rats were divided into four groups... more

The aim of this study was to analyze the effect of laser or light-emitting diode (LED) phototherapy on the bone formation at the midpalatal suture after rapid maxilla expansion. Twenty young adult male rats were divided into four groups with 8 days of experimental time: group 1, no treatment; group 2, expansion; group 3, expansion and laser irradiation; and group 4, expansion and LED irradiation. In groups 3 and 4, light irradiation was in the first, third, and fifth experimental days. In all groups, the expansion was accomplished with a helicoid 0.020″ stainless steel orthodontic spring. A diode laser (λ780 nm, 70 mW, spot of 0.04 cm2, t = 257 s, spatial average energy fluence (SAEF) of 18 J/cm2) or a LED (λ850 nm, 150 mW ± 10 mW, spot of 0.5 cm2, t = 120 s, SAEF of 18 J/cm2) were used. The samples were analyzed by Raman spectroscopy carried out at midpalatal suture and at the cortical area close to the suture. Two Raman shifts were analyzed: ∼960 (phosphate hydroxyapatite) and ∼1,450 cm−1 (lipids and protein). Data was submitted to statistical analysis. Significant statistical difference (p ≤ 0.05) was found in the hydroxyapatite (CHA) peaks among the expansion group and the expansion and laser or LED groups. The LED group presented higher mean peak values of CHA. No statistical differences were found between the treated groups as for collagen deposition, although LED also presented higher mean peak values. The results of this study using Raman spectral analysis indicate that laser and LED light irradiation improves deposition of CHA in the midpalatal suture after orthopedic expansion.

To determine the most effective position jaundiced neonates should assume during phototherapy from appraised randomised controlled trials. Many local hospitals still alternate positions of jaundiced neonates receiving phototherapy despite... more

To determine the most effective position jaundiced neonates should assume during phototherapy from appraised randomised controlled trials. Many local hospitals still alternate positions of jaundiced neonates receiving phototherapy despite the safe infant sleeping protocol of placing them supine. A systematic review was conducted. Databases that included Cumulative Index to Nursing and Allied Health Literature, ScienceDirect, Embase and The Cochrane Library were used. Randomized controlled trials published in English language that evaluate the best position for healthy jaundiced neonates aged day 1 to 14 under phototherapy were searched. In addition, any positioning done every 2-3 hours during phototherapy with the outcome measures being bilirubin reduction and duration of phototherapy were also searched and included (n = 5). Physiotherapy Evidence Database scale was adopted for quality assessment. All processes were conducted by both reviewers independently. Discrepancies were resol...

Facial telangiectasia and other vascular lesions have historically been effectively treated with the pulsed dye laser (PDL). This study compares the safety and efficacy of the PDL to an intense pulsed-light (IPL) handpiece with dual-band... more

Facial telangiectasia and other vascular lesions have historically been effectively treated with the pulsed dye laser (PDL). This study compares the safety and efficacy of the PDL to an intense pulsed-light (IPL) handpiece with dual-band spectral absorption, shorter pulse widths, and constant output power. Sixteen subjects were enrolled with facial telangiectasia in this single-site study. Subjects were randomized to receive up to two split-face treatments 1 month apart with PDL on one side and IPL on the other. PDL treatments were performed at 595 nm with either a 10 or 7 mm spot at a fluence range of 8.1-14.5 J/cm(2), and either 10 or 40 mseconds pulse width. Zimmer air cooling (setting of 4) and ultrasound gel were used for patient comfort. IPL treatments were performed with a spectral range of 500-670 and 870-1,200 nm, a 10 mm × 15 mm spot, fluence range of 34-70 J/cm(2), either a 10 or 100 mseconds pulse width, and 5°C contact cooling. Safety assessments were conducted by the study investigator immediately, 48-96 hours and 1-2 months post-treatment. Independent, blinded-review assessments were conducted 3 months post-treatment. Efficacy was evaluated using a seven-point Telangiectasia Grading Scale (TGS: -1 to 5). Subject self-assessment data were also collected. The difference in incidence rate and severity of adverse side effects between the two devices were not statistically significant (P ≥ 0.39, Fisher&amp;amp;#39;s exact test) at any of the three evaluation periods. Per blinded-review assessment, the mean TGS score for both devices was 3.3 (IPL 95% CI: 2.8-3.7; PDL 95% CI: 2.9-3.8). The difference in blinded-ratings for the two devices were not statistically significant (P = 0.82, ANOVA for repeated measures). The IPL studied here successfully treated facial telangiectasia, resulting in equivalent safety and efficacy outcomes as compared to the PDL.

The colloidal solutions of the gold nanoparticles (GNPs) were prepared with double deionized water (DDDW), and Dulbecco’s Modified Medium (DMEM) solution (pH=7.2-7.4), using pulsed laser ablation in the liquid phase (PLAL), with 1064 nm... more

The colloidal solutions of the gold nanoparticles (GNPs) were prepared with double deionized water (DDDW), and Dulbecco’s Modified Medium
(DMEM) solution (pH=7.2-7.4), using pulsed laser ablation in the liquid
phase (PLAL), with 1064 nm Nd-YAG laser, and energies (300, 400, 500
and 600) mJ and the laser spot intensity of laser (6.11, 8.15, 10.19 and
12.23) J.cm-2 respectively. The number of applied pulses associated with these energies were (100, 150, 250 and 300) pulses, respectively. The repetition rate and the pulse duration were (10 ns) and (6Hz), respectively for the both solutions.
The surface plasmonic resonance (SPR) peaks of GNPs were found to
be located between (509 to 524) nm and (549 to 580) nm for those prepared with DDDW and DMEM respectively.
The concentration and the size of GNPs in the colloidal depended on
both of the pulses number and laser energy. The concentration values were found to be between (4-142) ppm with DDDW and (6.2-16.2) ppm with DMEM.
The prepared GNPs with DDDW were found between (3.5 and 27) nm diameters, while those prepared with DMEM were (59 to 116) nm diameters. The variation in diameter ( with the TEM and specrumic) calculations was acceptable with statistical error, while for DLS shows a large variation. So, the size of particles affected by absorbed laser energy before attracting with the original target.
The biological effects of GNPs were tested on the Hela and SR lines cancer cells, which were cultured in 96-well plates, and incubated for 24h in 37oC with (25, 50 and 75)% concentration of the colloidal solutions.
The statistical analysis showed large dependence of the photothermal therapy (PTT) on the size, concentration of GNPs, and the irradiation time of IR.