BAALC (original) (raw)
BAALC is a gene that codes for the: brain and acute leukemia cytoplasmic protein. The official symbol (BAALC) and official name (brain and acute leukemia cytoplasmic) is maintained by the HGNC. The function of BAALC is not fully understood yet but has been suggested to have synaptic roles involving the post synaptic lipid raft. Lipid rafts are microdomains that are enriched with cholesterol and sphingolipids, lipid raft functions include membrane trafficking, signal processing, and regulation of the actin cytoskeleton. The postsynaptic lipid raft possesses many proteins and is one of the major sites for signal processing and postsynaptic density (PSD). Along with its involvement in the post synaptic lipid rafts, BAALC expression has been associated with Acute Lymphoblastic Leukemia and Acu
| Property | Value |
|---|---|
| dbo:abstract | BAALC is a gene that codes for the: brain and acute leukemia cytoplasmic protein. The official symbol (BAALC) and official name (brain and acute leukemia cytoplasmic) is maintained by the HGNC. The function of BAALC is not fully understood yet but has been suggested to have synaptic roles involving the post synaptic lipid raft. Lipid rafts are microdomains that are enriched with cholesterol and sphingolipids, lipid raft functions include membrane trafficking, signal processing, and regulation of the actin cytoskeleton. The postsynaptic lipid raft possesses many proteins and is one of the major sites for signal processing and postsynaptic density (PSD). Along with its involvement in the post synaptic lipid rafts, BAALC expression has been associated with Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia. (en) BAALC (англ. BAALC, MAP3K1 and KLF4 binding) – білок, який кодується однойменним геном, розташованим у людей на 8-й хромосомі. Довжина поліпептидного ланцюга білка становить 180 амінокислот, а молекулярна маса — 19 224. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Кодований геном білок за функцією належить до ліпопротеїнів. Задіяний у такому біологічному процесі, як альтернативний сплайсинг. Локалізований у клітинній мембрані, цитоплазмі, мембрані, клітинних контактах, синапсах, . (uk) |
| dbo:arm | q |
| dbo:band | 22.3 |
| dbo:chromosome | 8 |
| dbo:entrezgene | 79870 |
| dbo:hgncid | 14333 |
| dbo:omim | 606602 (xsd:integer) |
| dbo:refseq | NP_001019543.1 NP_079088.1 |
| dbo:symbol | BAALC |
| dbo:thumbnail | wiki-commons:Special:FilePath/Ideogram_human_chromosome_8.svg?width=300 |
| dbo:uniprot | Q8WXS3 |
| dbo:wikiPageID | 18791403 (xsd:integer) |
| dbo:wikiPageLength | 15179 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1081647966 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Caenorhabditis_elegans dbr:Neoplasm dbr:Progenitor_cell dbr:Cytoskeleton dbr:DNA dbr:Saccharomyces_cerevisiae dbr:Protein_isoform dbr:Gene_expression_profiling dbr:Neocortex dbr:Glycine dbr:Myocyte dbr:Apoptosis dbr:Hematopoietic_stem_cell dbr:CAMK2A dbr:CD34 dbr:Actin dbr:Drosophila_melanogaster dbr:HOXA9 dbr:Lipid_raft dbr:Acute_lymphoblastic_leukemia dbr:Acute_myeloid_leukemia dbr:Amino_acid dbr:Cysteine dbr:Central_nervous_system dbr:Hippocampus dbr:Prognosis dbr:RNA dbr:Real-time_polymerase_chain_reaction dbr:HUGO_Gene_Nomenclature_Committee dbr:Stem-loop dbr:Cholesterol dbr:Translation_(biology) dbr:Autophosphorylation dbr:Bone_marrow dbr:Ca2+/calmodulin-dependent_protein_kinase_II dbr:IGFBP7 dbr:Chromosome_8_(human) dbr:Neuroectoderm dbr:Exon dbr:IDH1 dbr:IDH2 dbr:Sphingolipid dbr:Myeloid_tissue dbr:Myristoylation dbr:N-terminus dbr:Postsynaptic_density dbr:Palmitoylation dbr:Surrogate_marker dbr:File:BAALC_Gene_on_Chromosome_8.png dbr:File:Ideogram_human_chromosome_8.svg |
| dbp:arm | q (en) |
| dbp:band | 22.300000 (xsd:double) |
| dbp:chromosome | 8 (xsd:integer) |
| dbp:entrezgene | 79870 (xsd:integer) |
| dbp:hgncid | 14333 (xsd:integer) |
| dbp:name | brain and acute leukemia, cytoplasmic (en) |
| dbp:omim | 606602 (xsd:integer) |
| dbp:refseq | NP_001019543.1 NP_079088.1 (en) |
| dbp:symbol | BAALC (en) |
| dbp:uniprot | Q8WXS3 (en) |
| dbp:wikiPageUsesTemplate | dbt:Reflist dbt:Short_description dbt:Infobox_protein |
| gold:hypernym | dbr:Gene |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 dbo:Protein umbel-rc:ProteinMolecule |
| rdfs:comment | BAALC is a gene that codes for the: brain and acute leukemia cytoplasmic protein. The official symbol (BAALC) and official name (brain and acute leukemia cytoplasmic) is maintained by the HGNC. The function of BAALC is not fully understood yet but has been suggested to have synaptic roles involving the post synaptic lipid raft. Lipid rafts are microdomains that are enriched with cholesterol and sphingolipids, lipid raft functions include membrane trafficking, signal processing, and regulation of the actin cytoskeleton. The postsynaptic lipid raft possesses many proteins and is one of the major sites for signal processing and postsynaptic density (PSD). Along with its involvement in the post synaptic lipid rafts, BAALC expression has been associated with Acute Lymphoblastic Leukemia and Acu (en) BAALC (англ. BAALC, MAP3K1 and KLF4 binding) – білок, який кодується однойменним геном, розташованим у людей на 8-й хромосомі. Довжина поліпептидного ланцюга білка становить 180 амінокислот, а молекулярна маса — 19 224. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk) |
| rdfs:label | BAALC (en) BAALC (uk) |
| owl:sameAs | freebase:BAALC wikidata:BAALC http://tt.dbpedia.org/resource/BAALC dbpedia-uk:BAALC https://global.dbpedia.org/id/k2Zk |
| prov:wasDerivedFrom | wikipedia-en:BAALC?oldid=1081647966&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/BAALC_Gene_on_Chromosome_8.png wiki-commons:Special:FilePath/Ideogram_human_chromosome_8.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:BAALC |
| is dbo:wikiPageWikiLink of | dbr:List_of_human_protein-coding_genes_1 |
| is foaf:primaryTopic of | wikipedia-en:BAALC |
