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New Journal of Chemistry, 2019
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The N···H hydrogen bond strength in the transition state at the limiting step determines the reactivity of cephalosporins in the active site of L1 metallo-β-lactamase
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Mendeleev Communications, 2019
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Benchmark studies of hydrogen bond governing reactivity of cephalosporins in L1 metallo‐β‐lactamase: Efficient and reliable QSPR equations
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International Journal of Quantum Chemistry, 2020
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Electronic Steric Factors in the Active Site of Metallo-β-Lactamase and Reactivity of Cephalosporin Antibiotics
Vladimir Tsirelson
Moscow University Chemistry Bulletin, 2019
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Cephalosporin Substrate Specificity Determinants of TEM-1 beta -Lactamase
T. Palzkill
Journal of Biological Chemistry, 1997
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Stability of TEM β-lactamase mutants hydrolyzing third generation cephalosporins
Jean-marie Frère
Proteins: Structure, Function, and Genetics, 1995
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Effect of Substituents in Hydrolyzed Cephalosporins on Intramolecular O–H···N Bond
Vladimir Tsirelson
Russian Journal of Physical Chemistry A, 2020
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β-Lactamase-catalysed hydrolysis of cephalexin: evolution of the cephalosporoate intermediate
J. Frau, Josefa Donoso
Journal of the Chemical Society, Perkin Transactions 2, 1997
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Computational analysis of the interactions of a novel cephalosporin derivative with β-lactamases
Margherita De Rosa
BMC Structural Biology
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Computational Calculations of Molecular Properties and Molecular Docking of New and Reference Cephalosporins on Penicillin Binding Proteins and Various β-Lactamases
Journal of Pharmacy and Pharmacology
Journal of Pharmacy and Pharmacology 4 (2016) 212-225, 2016
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Structure of a cephalosporin synthase
Inger Andersson
Nature, 1998
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Coupling Reactions of Cephalosporin Sulfones: A Stable 3-Stannylated Cephem
John Buynak
Organic Letters, 2001
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Molecular Dynamics Simulations of the TEM-1 β-Lactamase Complexed with Cephalothin
Natalia Diaz
Journal of Medicinal Chemistry, 2005
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Theoretical studies of the hydrolysis of antibiotics catalyzed by a metallo-β-lactamase
Silvia Castillo
Archives of Biochemistry and Biophysics, 2015
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The inhibition of metallo-β-lactamase by thioxo-cephalosporin derivatives
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Bioorganic & Medicinal Chemistry Letters, 2004
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The structural basis of cephalosporin formation in a mononuclear ferrous enzyme
Inger Andersson, Linda Öster, Graziella Ranghino
Nature Structural & Molecular Biology, 2003
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Quantum Mechanical Approach for the Catalytic Mechanism of Dinuclear Zinc Metallo-β-lactamase by Penicillin and Cephalexin: Kinetic and Thermodynamic Points of View
Mina Ghiasi
Physical Chemistry Research, 2017
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Role of β-lactam carboxyl group on binding of penicillins and cephalosporins to class C β-lactamases
Josefa Donoso, J. Frau
Proteins: Structure, Function, and Genetics, 2003
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Mechanism of inhibition of the PC1 .beta.-lactamase of Staphylococcus aureus by cephalosporins: importance of the 3'-leaving group
rex pratt
Biochemistry, 1985
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Synthesis, characterization and biological activities of cephalosporin metals complexes International Journal of Biosciences | IJB
Zeeshan Anjum, Rehmat Zaman
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Mechanism of Meropenem Hydrolysis by New Delhi Metallo β-Lactamase
ravi tripathi
ACS Catalysis, 2015
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The 2.0 Å Crystal Structure of Cephalosporin Acylase
Ki-Hong Yoon
Structure, 2000
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On the mechanism of cephalosporin isomerization
Emil Popa
Journal of Molecular Structure-theochem, 1994
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Exploring the role of L209 residue in the active site of NDM-1 a metallo-β-lactamase
Gianfranco Amicosante
PLOS ONE, 2018
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Calorimetric Analysis of Cephalosporins Using an Immobilized TEM-1 [beta]-Lactamase on Ni2+ Chelating Sepharose Fast Flow
Virapong Prachayasittikul
Analytical …, 2001
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Binding of cephalothin and cefotaxime to D-Ala-D-Ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum .beta.-lactamases
Alexandre Kuzin
Biochemistry, 1995
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Multiple substitutions at position 104 of β -lactamase TEM-1: assessing the role of this residue in substrate specificity
Laurent Maveyraud
Biochemical Journal, 1995
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Crystallographic Structure of a Phosphonate Derivative of the Enterobacter cloacae P99 Cephalosporinase: Mechanistic Interpretation of a .beta.-Lactamase Transition-State Analog
rex pratt
Biochemistry, 1994
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Trapping and Characterization of a Reaction Intermediate in Carbapenem Hydrolysis by B. cereus Metallo-β-lactamase
Ernesto Mata
Journal of the American Chemical Society, 2008
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Synthesis of New Cephalosporins of Expected Improved Activity and Resistance Against -Lactamases
Shakir Alwan
Iraqi Journal of Pharmaceutical Sciences, 2014
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The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening
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Bioorganic & Medicinal Chemistry Letters, 2011
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The Evolution of Cefotaximase Activity in the TEM β-Lactamase
Brian Dominy
Journal of Molecular Biology, 2012
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Synthesis and biological evaluation of the progenitor of a new class of cephalosporin analogues, with a particular focus on structure-based computational analysis
Giovanni Vigliottá
PLOS ONE, 2017
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Ceftibuten stability to active-site serine and metallo-β-lactamases
Gianfranco Amicosante
International Journal of Antimicrobial Agents, 2001
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Cephalosporins: A Focus on Side Chains and β-Lactam Cross-Reactivity
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Pharmacy, 2019
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