PPV Research Papers - Academia.edu (original) (raw)

Sharka, caused by Plum Pox Virus (PPV), is by far the most important infectious disease of peach [P. persica (L.) Batsch] and other Prunus species. The progressive spread of the virus in many important growing areas throughout Europe... more

Sharka, caused by Plum Pox Virus (PPV), is by far the most important infectious disease of peach [P. persica (L.) Batsch] and other Prunus species. The progressive spread of the virus in many important growing areas throughout Europe poses serious issues to the economic sustainability of stone fruit crops, peach in particular. The adoption of internationally agreed-upon rules for diagnostic tests, strain-specific monitoring schemes and spatial–temporal modeling of virus spread, are all essential for a more effective sharka containment. The EU regulations on nursery activity should be modified based on the zone delimitation of PPV presence, limiting open-field production of propagation materials only to virus-free areas. Increasing the efficiency of preventive measures should be augmented by the short-term development of resistant cultivars. Putative sources of resistance/tolerance have been recently identified in peach germplasm, although the majority of novel resistant sources to PPV-M have been found in almond. However, the complexity of introgression from related-species imposes the search for alternative strategies. The use of genetic engineering, particularly RNA interference (RNAi)-based approaches, appears as one of the most promising perspectives to introduce a durable resistance to PPV in peach germplasm, notwithstanding the well-known difficulties of in vitro plant regeneration in this species. In this regard, rootstock transformation to induce RNAi-mediated systemic resistance would avoid the transformation of numerous commercial cultivars, and may alleviate consumer resistance to the use of GM plants.

To determine the outcomes of vitreoretinal surgery after choroidal tumor biopsy. Retrospective, single-center, consecutive case series. A total of 739 consecutive patients undergoing choroidal tumor biopsy. All subjects who underwent... more

To determine the outcomes of vitreoretinal surgery after choroidal tumor biopsy. Retrospective, single-center, consecutive case series. A total of 739 consecutive patients undergoing choroidal tumor biopsy. All subjects who underwent transretinal or transscleral choroidal tumor biopsy for diagnostic or prognostic purposes between May 1993 and May 2013 were identified in our database. We then reviewed patients who subsequently required secondary vitreoretinal surgery for complications arising from such biopsies. Reason for vitreoretinal surgery, association with biopsy procedure, best-corrected visual acuity (BCVA; logarithm of the minimum angle of resolution [logMAR]), intraocular or extrascleral tumor dissemination, resolution of vitreous hemorrhage, reattachment of the retina with a single vitreoretinal procedure, number of additional vitrectomies undertaken, and number of enucleations. A total of 20 of 739 eyes (2.7%) underwent vitreoretinal surgery for complications arising from...

In this research, experimental applications have been performed to reduce blast induced vibrations in open pit mines. For this purpose, artificial discontinuity zones such as barrier holes and trench were opened in a dragline panel of... more

In this research, experimental applications have been performed to reduce blast induced vibrations in open pit mines. For this purpose, artificial discontinuity zones such as barrier holes and trench were opened in a dragline panel of Seyitomer Lignite Enterprise, Kutahya, Turkey. Peak particle velocities in front of and behind them were measured by seismographs. In this way, their effect against vibration was observed and compared. Barrier holes were opened 24 m deep through 3 parallel lines and aligned at 1 m spacing. On the other hand, the trench had 8 m depth and 4 m width. During the research, 209 measurements were taken belonging to 105 explosions. Twenty-eight explosions were carried out in the barrier holes experiments and 77 explosions were carried out in the trench experiments. A decrease in vibration of 14.3–18.5% was obtained behind the barrier holes while a decrease of 24.8–58.1% was provided by the trench.

Influenza vaccination is now recommended for all ages; CDC pneumococcal polysaccharide vaccination (PPV) recommendations are comorbidity-based in nonelderly patients. We constructed a Markov model to estimate the cost-effectiveness of... more

Influenza vaccination is now recommended for all ages; CDC pneumococcal polysaccharide vaccination (PPV) recommendations are comorbidity-based in nonelderly patients. We constructed a Markov model to estimate the cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds. Patients were followed for 10 years, with differing time horizons examined in sensitivity analyses. With 100% vaccine uptake, dual vaccination cost 37,700/QALYgainedcomparedtoaCDCrecommendationstrategy;withobservedvaccineuptake,dualvaccinationcost37,700/QALY gained compared to a CDC recommendation strategy; with observed vaccine uptake, dual vaccination cost 37,700/QALYgainedcomparedtoaCDCrecommendationstrategy;withobservedvaccineuptake,dualvaccinationcost5,300/QALY. Results were sensitive to shorter time horizons, favoring CDC recommendations. We found dual vaccination of all 50-year-olds economically reasonable. Shorter duration models may not fully account for PPV effectiveness.

ABSTRACT This review highlights recent developments in the grafting of conjugated polymers onto various substrates for organic electronic devices. The rapid development of multi-layer architectures demands the preparation of well-defined... more

ABSTRACT This review highlights recent developments in the grafting of conjugated polymers onto various substrates for organic electronic devices. The rapid development of multi-layer architectures demands the preparation of well-defined interfaces between both compatible and incompatible materials. It is promising therefore that interface-engineering is now known to help passivate charge trap states, control energy level alignments, enhance charge extraction, guide active-layer morphologies, and improve material compatibility, adhesion and device stability. In organic electronic devices, conjugated polymers are in contact with a wide range of constituents, such as metals, metal oxides, organic materials, and inorganic particles. Covalent bonds between these materials and macromolecules are desired to yield intimate contacts and well-defined interfaces. Following an overview of the various synthetic methodologies of conjugated polymers, the chemistry of tethering macromolecular chains onto nanoparticles and flat surfaces is described. The creation of functional hybrid materials offers the potential to deliver efficient and low-cost devices.