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References

Aghajanian, G. K. & Bunney, B. S. (1977) Dopamine “autoreceptors”: Pharmacological characterization by microiontophoretic single cell recording studies. Naunyn-Schmiedeberg's Archives of Pharmacology 297:1–7. [DCG]CrossRefGoogle ScholarPubMed

Ahlenius, S. (1979) An analysis of behavioral effects produced by drug-induced changes of dopaminergic neurotransmission in the brain. Scandinavian Journal of Psychology 20:59–64. [taRAW]CrossRefGoogle ScholarPubMed

Ahlenius, S., Engel, J. & Zoller, M. (1977) Effects of apomorphine and haloperidol on exploratory behavior and latent learning in mice. Physiological Psychology 5:290–94. [RJB, taRAW]CrossRefGoogle Scholar

Allison, J., Miller, M. & Wozny, M. (1979) Conservation in behavior. Journal of Experimental Psychology: General 108:4–34. [HMS]CrossRefGoogle Scholar

Amaral, D. G. & Routtenberg, A. (1975) Locus coeruleus and intracranial self-stimulation: A cautionary note. Behavioral Biology 13:331–38. [rRAW]CrossRefGoogle ScholarPubMed

Amsel, A. (1958) The role of frustrative nonreward in noncontinuous reward situations. Psychopharmacology Bulletin 55:102–19. [WJF]Google ScholarPubMed

Amsel, A. (1967) Partial reinforcement effects on vigor and persistence. In: The psychology of learning and motivation, vol. 1, ed. Spence, K. W. & Spence, J. T., New York: Academic Press. [RLM]Google Scholar

Amsel, A., Rashotte, M. E. & MacKinnon, J. R. (1966) Partial reinforcement effects within a subject and between subjects. Psychological Monographs: General and Applied 80:1–39. [WJF]CrossRefGoogle ScholarPubMed

Amsel, A. & Roussel, J. (1952) Motivational properties of frustration: 1. Effect on a running response of the addition of frustration to the motivational complex, Journal of Experimental Psychology 43:363–68. [GFK, taRAW]CrossRefGoogle Scholar

Andén, N.-E., Fuxe, K., Hamberger, B. & Hökfelt, T. (1966) A quantitative study of the nigro-neostriatal dopamine neuron system in the rat. Acta Physiologica Scandinavica 67:306–12. [DCG]CrossRefGoogle ScholarPubMed

Angrist, B., Sathananthan, G., Wilk, S. & Gershon, S. (1974) Amphetamine psychosis: Behavioral and biochemical aspects. Journal of Psychiatric Research 11:13–23. [PRS]CrossRefGoogle ScholarPubMed

Anisman, H., Irwin, J. & Sklar, L. S. (1979) Deficits of escape performance following catecholamine depletion: Implications for behavioral deficits induced by uncontrollable stress. Psychopharmacology 64:163–70. [HA]CrossRefGoogle Scholar

Anisman, H., Remington, G. & Sklar, L. S. (1979) Effect of inescapable shock on subsequent escape performance: Catecholaminergic and cholinergic mediation of response initiation and maintenance. Psychopharmacology 61:107–24. [HA]CrossRefGoogle ScholarPubMed

Baldessarini, R. J. (1980) Drugs and the treatment of psychiatric disorders. In: The pharmacological basis of therapeutics, 6th ed., ed. Gilman, A. G., Goodman, L. S. & Gilman, A., pp. 395–418. New York: MacMillan. [RHR]Google Scholar

Baxter, B. L., Gluckman, M. I., Stein, L. & Scerni, R. A. (1974) Self-injection of apomorphine in the rat: Positive reinforcement by a dopamine receptor stimulant. Pharmacology, Biochemistry and Behavior 2:387–93. [taRAW]CrossRefGoogle ScholarPubMed

Belluzzi, J. D. & Stein, L. (1977) Enkephalin may mediate euphoria and drive-reduction reward. Nature 266:556–58. [taRAW]CrossRefGoogle ScholarPubMed

Beninger, R. J., MacLennan, A. J. & Pinel, J. P. J. (1980) The use of conditioned defensive burying to test the effects of pimozide on associative learning. Pharmacology, Biochemistry and Behavior 12:445–48. [RJB, taRAW]CrossRefGoogle ScholarPubMed

Beninger, R. J., Mason, S. T., Phillips, A. G. & Fibiger, H. C. (1980) The use of conditioned suppression to evaluate the nature of neuroleptic-induced avoidance deficits. Journal of Pharmacology and Experimental Therapeutics 213:623–27. [RJB, taRAW]Google ScholarPubMed

Beninger, R. J. & Phillips, A. G. (1980) The effect of pimozide on the establishment of conditioned reinforcement. Psychopharmacology 68:147–53. [RJB]CrossRefGoogle ScholarPubMed

Beninger, R. J. & Phillips, A. G. (1981) The effects of pimozide during pairing on the transfer of classical conditioning to an operant discrimination. Pharmacology, Biochemistry and Behavior 14:101–05. [RJB, PS]CrossRefGoogle Scholar

Bignami, G. (1978) Effects of neuroleptics, ethanol, hypnotic-sedatives, tranquilizers, narcotics and minor stimulants in aversive paradigms. In: Psychopharmacology of aversively motivated behavior, ed. Anisman, H. & Bignami, G., pp. 385–402. New York: Plenum Press. [RHR]CrossRefGoogle Scholar

Bindra, D. A. (1974) A motivational view of learning, performance, and behavior modification. Psychological Review 81:199–213. [RLM, RHR, taRAW]CrossRefGoogle ScholarPubMed

Bolles, R. C. (1972) Reinforcement, expectancy, and learning. Psychological Review 79:394–409. [taRAW]CrossRefGoogle Scholar

Bowman, W. C. & Rand, M. J. (1980) Textbook of pharmacology, 2nd ed., pp. 15, 12 ff. Oxford: Blackwell. [WL]Google Scholar

Bozarth, M. A. (1982) Opiate reward mechanisms mapped by intracranial self-administration. In: Neurobiology of Opiate Reward Mechanisms, ed. Smith, J. E. and Lane, J. D., New York: Raven Press. [rRAW]Google Scholar

Bozarth, M. A. & Wise, R. A. (1981a) Intracranial self-administration of morphine into the ventral tegmental area in rats. Life Sciences 28:551–55. [rRAW]CrossRefGoogle ScholarPubMed

Bozarth, M. A. & Wise, R. A. (1981b) Localization of the reward-relevant opiate receptors. In: Problems of Drug Dependence, ed. Harris, L. S.. Washington, D.C.: National Institute on Drug Abuse. [rRAW]Google Scholar

Bozarth, M. A. & Wise, R. A. (1981c) Heroin reward is dependent on a dopaminergic substrate. Life Sciences 29:1881–86. [rRAW]CrossRefGoogle ScholarPubMed

Broekkamp, C. L. E. & Van Rossum, I. M. (1975) The effect of microinjections of morphine and haloperidol into the neostriatum and the nucleus accumbens on self-stimulation behavior. Archives Internationales de Pharmacodynamie et de Therapie 217:110–17. [WRK]Google Scholar

Bunney, B. S. & Grace, A. A. (1978) Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity. Life Sciences 23:1715–28. [DCG]CrossRefGoogle ScholarPubMed

Bunney, B. S., Walters, J. R., Roth, R. H. & Aghajanian, G. K. (1973) Dopaminergic neurons: Effect of antipsychotic drugs and amphetamine on single cell activity. Journal of Pharmacology and Experimental Therapeutics 185:560–71. [DGG]Google ScholarPubMed

Capaldi, E. J. (1967) A sequential hypothesis of instrumental learning. In: The psychology of learning and motication, vol. I., ed. Spence, K. W. & Spence, J. T., pp. 67–156. New York: Academic Press. [RLM]Google Scholar

Capaldi, E. J. & Waters, R. W. (1970) Conditioning and non-conditioning interpretations of small-trial phenomena. Journal of Experimental Psychology 84:518–22. [RLM]CrossRefGoogle Scholar

Capaldi, E. J., Ziff, D. R. & Godbout, R. C. (1970) Extinction and the necessity of nonnecessity of anticipating reward or nonrewarded trials. Psychonomic Science 18:61–63. [RLM]CrossRefGoogle Scholar

Carr, A. C. (1964) Psychological defect and psychological testing. In: Schizophrenia, ed. Kolb, L. C., Kellman, F. J. & Polatin, P., pp. 773–98. Boston: Little, Brown & Co. [CBN]Google Scholar

Carroll, M. E., France, C. P. & Meisch, R. A. (1979) Food deprivation increases oral and intravenous drug intake in rats. Science 205:319–21. [WRK]CrossRefGoogle ScholarPubMed

Casey, J. F., Bennett, I. F., Lindley, C. J., Hollister, L. E., Gordon, M. H. & Springer, N. N. (1960) Drug therapy in schizophrenia. Archives of General Psychiatry 2:210–20. [WJF]CrossRefGoogle ScholarPubMed

Cheramy, A., Leviel, V. & Glowinski, J. (1981) Dendritic release of dopamine in the substantia nigra. Nature 289:537–42. [DCG]CrossRefGoogle ScholarPubMed

Christie, J. E., Ljungberg, T. & Ungerstedt, U. (1973) Dopamine neurones and electrical self-stimulation in the lateral hypothalamus. Journal of Physiology 234:80P. [GWA]Google Scholar

Clare, G., Simeon, J. & Fink, M. (1969) Liquid butaperazine in the treatment of chronic psychosis in a mental health clinic. Current Therapeutic Research 11:57–63. [WJF]Google Scholar

Clavier, R. M., Fibiger, H. C. & Phillips, A. G. (1976) Evidence that self-stimulation of the region of the locus coeruleus in rats does not depend upon noradrenergic projections to telencephalon. Brain Research. 113:71–81. [rRAW]CrossRefGoogle Scholar

Clavier, R. M. & Routtenberg, A. (1974) Ascending monoamine-containing fiber pathways related to intracranial self-stimulation histochemical fluorescence study. Brain Research 72:25–10. [rRAW]CrossRefGoogle Scholar

Clody, D. E. & Beer, B. (1975) Conditioned avoidance: A predictor of efficacy and duration of action for long-acting neuroleptic agents. In: Predictability in psychopharmacology: Preclinical and clinical correlations, ed. Sudilovsky, A., Gershon, S. & Beer, B.. pp. 213–24. New York: Raven Press. [JL]Google Scholar

Commissaris, R. L., Lyness, W. H., Moore, K. E. & Rech, R. H. (1981) Central 5-hydroxytryptamine and the effects of hallucinogens and phenobarbital on operant responding in rats. Pharmacology, Biochemistry and Behavior 14:595–601. [WHL]CrossRefGoogle ScholarPubMed

Cook, L. & Kelleher, R. T. (1963) Effects of drugs on behavior. Annual Review of Pharmacology 3:205–22. [RJB]CrossRefGoogle Scholar

Corbett, D., Skelton, R. W. & Wise, R. A. (1977) Dorsal bundle lesions fail to disrupt self-stimulation from the region of locus coeruleus. Brain Research 133:37–44. [rRAW]CrossRefGoogle ScholarPubMed

Corbett, D. & Wise, R. A. (1979) Intracranial self-stimulation in relation to the ascending noradrenergic fiber systems of the pontine tegmentum and caudal midbrain: A moveable electrode mapping study. Brain Research 177:423–36. [rRAW]CrossRefGoogle Scholar

Costall, B. & Naylor, R. J. (1981) The hypotheses of different dopamine receptor mechanisms. Life Sciences 28:215–19. [PS]CrossRefGoogle Scholar

Costall, B. & Naylor, R. J. (1979) Behavioral aspects of dopamine agonists and antagonists. In: The neurobiology of dopamine, ed. Horn, A. S., Korf, J. & Westerink, B. H. C., pp. 555–76. New York: Academic Press. [RJB]Google Scholar

Cotman, C. W. & McGaugh, J. L. (1980) Behavioral neuroscience: An introduction, pp. 326–32. New York: Academic Press. [WL]Google Scholar

Crider, A. (1979) Schizophrenia: A biopsychological perspective. Hillsdale, N.J.: Lawrence Erlbaum. [PRS]Google Scholar

Crider, A., Solomon, P. R. & McMahon, M. (1981) Disruption of selective attention in the rat following chronic d-amphetamine administration: Relationship to schizophrenic attention disorder. Biological Psychiatry, submitted for publication. [PRS]Google Scholar

Crossland, J. (1970) Lewis's Pharmacology, 4th ed., pp. 744–51. Edinburgh: Livingstone. [WL]. American Journal of Psychology 93:41–51. [RLM]CrossRefGoogle Scholar

Hamill, W. T. & Fontana, A. F. (1975) The immediate effects of chlorpromazine in newly admitted schizophrenic patients. American Journal of Psychiatry 132:1023–26. [WJF]Google ScholarPubMed

Hamilton, M. H., Garcia-Munoz, M., Muir, W. J. & Arbuthnott, G. W. (1981) Separation of motor and other effects of unilateral 6-OHDA lesions. Neuroscience Letters (suppl. 6). In press. [GWA]Google Scholar

Head, H. (1920) Studies in Neurology. London: Oxford University Press. [rRAW]Google Scholar

Hebb, D. O. (1956) Drives and the CNS (conceptual nervous system). Psychological Review 62:243–54. [taRAW]CrossRefGoogle Scholar

Hebb, D. O. (1972) Textbook of psychology, third ed.Philadelphia: W. B. Saunders. [AE]Google Scholar

Henke, P. (1973) Effects of reinforcement omission on rats with lesions in the amygdala. Journal of Comparative and Physiological Psychology 84:187–93. [GFK]CrossRefGoogle Scholar

Herberg, L. J., Stephens, D. N. & Franklin, K. B. J. (1976) Catecholamines and self-stimulation: Evidence suggesting a reinforcing role for noradrenaline and a motivating role for dopamine. Pharmacology Biochemistry & Behavior 4:575–82. [rRAW]CrossRefGoogle Scholar

Herling, S. & Woods, J. H. (1980) Chlorpromazine effects on cocaine reinforced responding in rhesus monkeys: Reciprocal modification of rate-altering effects of the drugs. Journal of Pharmacology and Experimental Therapeutics 214:354–61. [PS, taRAW]Google Scholar

Hill, R. T. & Tedeschi, D. H. (1971) Animal testing and screening procedures in evaluating psychotropic drugs. In: An introduction to psychopharmacology, ed. Rech, R. H. & Moore, K. E., pp. 261–68. New York: Raven Press. [RHR]Google Scholar

Hodge, G. K. & Butcher, L. L. (1980) Pars compacta of the substantia nigra modulates motor activity but is not involved importantly in regulating food and water intake. Naunyn-Schmiedeberg's Archives of Pharmacology 313:51–67. [DCG]CrossRefGoogle Scholar

Hoffmeister, F. H. & Wuttke, W. (1975) Psychotropic drugs as negative reinforcers. Pharmacology Reviews 27:419–28. [CBN]Google ScholarPubMed

Hökfelt, T., Rehfeld, J. F., Skirboll, Z., Ivemark, B., Goldstein, M. & Markey, K. (1980) Evidence for coexistence of dopamine and CCK in meso-limbic neurones. Nature 285:476–78. [DCG]CrossRefGoogle Scholar

Hollister, L. E. (1964) Adverse reactions to phenothiazines. Journal of the American Medical Association 189:311–13. [WJF]Google ScholarPubMed

Hunt, H. F. (1956) Some effects of drugs on classical (type S) conditioning. Annals of the New York Academy of Science 65:258–67. [RJB]CrossRefGoogle ScholarPubMed

Hursh, S. R. (1980) Economic concepts for the analysis of behavior. Journal of the Experimental Analysis of Behavior 34:219–38. [HMS]CrossRefGoogle ScholarPubMed

Irwin, J., Suissa, A. & Anisman, H. (1980) Differential effects of inescapable shock on escape performance and discrimination learning in a water escape task. Journal of Experimental Psychology: Animal Behavior Processes 6:21–40. [HA]Google Scholar

Iwamoto, E. T. & Way, E. L. (1977) Circling behavior and stereotypy induced by intracranial nigral opiate microinjections. Journal of Pharmacology and Experimental Therapeutics 203:347–59. [rRAW]Google Scholar

Janssen, P. A. J., Niemegeers, C. J. E., Schellekens, K. H. L., Dresse, A., Lenaerts, F. M., Pinchard, A., Schaper, W. K. A., Van Nueten, J. M. & Verbruggen, F. J. (1968) Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. Arzneimittel-Forschung 18:261–79. [WJF, GFK]Google ScholarPubMed

Jenkins, H. M. (1977) Sensitivity of different response systems to stimulus-reinforcer and response-reinforcer relations. In: Operant Pavlovian interactions, ed. Davis, H. & Hurwitz, H. M. B., pp. 78–96. Hillsdale, N.J.: Erlbaum. [RLM]Google Scholar

Jönsson, L., Änggard, E. & Gunne, L. (1971) Blockade of intravenous amphetamine euphoria in man. Clinical Pharmacology and Therapy 12:889–96. [taRAW]CrossRefGoogle ScholarPubMed

Kamin, L. J. (1968) “Attention-like” processes in classical conditioning. In: Miami symposium on the prediction of behavior, ed. Jones, M. R., pp. 9–31. Miami: University of Miami Press. [PRS]Google Scholar

Kandel, D. A. & Schuster, C. R. (1977) An investigation of nalorphine and perphenazine as negative reinforcers in an escape paradigm. Pharmacology, Biochemistry & Behavior 6:61–71. [CBN]CrossRefGoogle Scholar

Katz, R. J. (1981) The temporal structure of motivation 4. A reexamination of extinction effects in intracranial reward. Behavioral and Neural Biology 32:191–200. [RJK]CrossRefGoogle Scholar

Katz, R. J. & Bailey, E. D. (1980) A reexamination of apomorphine induced stereotypy in light of self-administration experiments in the rat. Progress in Neuropharmacology 3:483–90. [RJK]Google Scholar

Kelleher, R. T. & Morse, W. H. (1968) Determinants of the specificity of behavioral effects of drugs. Ergebnisse der Physiologie 60:1–56. [JL]Google ScholarPubMed

Kelleher, R. T. & Morse, W. H. (1968) Schedules using noxious stimuli. 3. Responding maintained with response produced electric shocks. Journal of Experimental Analysis of Behavior 11:819–38. [GFK]CrossRefGoogle ScholarPubMed

Kelly, P. H., Seviour, P. W. & Iversen, S. D. (1975) Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Research 94:507–22. [DCG]CrossRefGoogle ScholarPubMed

Kokkinidis, L. & Anisman, H. (1980) Amphetamine models of paranoid schizophrenia: An overview and elaboration of animal experimentation. Psychological Bulletin 88:551–79. [HA]CrossRefGoogle ScholarPubMed

Koob, G. F., Balcom, G. J. & Meyerhoff, J. L. (1976) Increases in intracranial self-stimulation in the posterior hypothalamus following unilateral lesions in the locus coeruleus. Brain Research 101:554–60. [rRAW]CrossRefGoogle ScholarPubMed

Koob, G. F., Fray, P. J. & Iversen, S. D. (1978) Self-stimulation at the lateral hypothalamus and locus coeruleus after specific unilateral lesions of the dopamine system. Brain Research 146:123–40. [GFK]CrossRefGoogle ScholarPubMed

Koob, G. F., Riley, S. J., Smith, S. C. & Robbins, T. W. (1978) Effects of 6-hydroxydopamine lesions of the nucleus accumbens septl and olfactory tuberele on feeding, locomotor activity, and amphetamine anorexia in the rat. Journal of Comparative Physiological Psychology 92:917–27. [GFK]CrossRefGoogle Scholar

Kornblith, C. L., Ervin, G. N. & King, R. A. (1978) Hypothalamic and locus coeruleus self-stimulation are decreased by cholecystokinin. Physiology and Behavior 21:1037–41. [DCG]CrossRefGoogle ScholarPubMed

Kuhar, M. J., Roth, R. H. & Aghajanian, G. K. (1976) Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions. Brain Research 35:167–76. [WHL]CrossRefGoogle Scholar

Kupfer, D. J., Wyatt, R. J., Synder, F. & Davis, J. M. (1971) Chlorpromazine and sleep in psychiatric patients. Archives of General Psychiatry 24:185–89. [WJF]CrossRefGoogle ScholarPubMed

Latz, A. & Kornetsky, C. (1965) The effects of chlorpromazine and secobarbital under two conditions of reinforcement on the performance of chronic schizophrenic subjects. Psychopharmacologia 7:77–88. [WJF]CrossRefGoogle ScholarPubMed

Liebman, J. M. & Butcher, L. L. (1974) Comparative involvement of dopamine and noradrenaline in rate-free self-stimulation in substantia nigra, lateral hypothalamus, and mesencephalic central gray. Nauyn-Schmiedeberg's Archives of Pharmacology 284:167–94. [WJF, taRAW]CrossRefGoogle ScholarPubMed

Liebman, J. M., Prowse, J. & Gerhardt, S. (1981) Effects of various catecholamine antagonists and nonspecific motor disruption on shuttlebox self-stimulation performance: A systematic comparison. Society for Neuro-science Abstracts 7:204. [JL]Google Scholar

Lorens, S. A. & Mitchell, C. L. (1973) Influence of morphine on lateral hypothalamic self-stimulation in the rat. Psychopharmacologia 32:271–77. [rRAW]CrossRefGoogle Scholar

Lyness, W. H., Demarest, K. T. & Moore, K. E. (1980) Effects of d-amphetamine and disruption of 5-hydroxytryptaminergic neuronal systems on the synthesis of dopamine in selected regions of the rat brain. Neuropharmacology 19:883–89. [WHL]CrossRefGoogle ScholarPubMed

Lyness, W. II, Friedle, N. M. & Moore, K. E. (1980) Increased self-administration of d-amphetamine after destruction of 5-hydroxy-tryptaminergie neurons. Pharmacology, Biochemistry and Behavior 12:937–41. [WHL]CrossRefGoogle ScholarPubMed

Lyness, W. II, Friedle, N. M. & Moore, K. E. (1979) Destruction of dopaminergic nerve terminals in nucleus accumbens: Effect on d-amphetamine self-administration. Pharmacology, Biochemistry and Behavior 11:553–56. [DCG, WHL, taRAW]CrossRefGoogle ScholarPubMed

Mackintosh, N. J. (1975) A theory of attention: Variations in the associability of stimuli with reinforcement. Psychological Review 82:276–98. [PRS]CrossRefGoogle Scholar

Mackintosh, N. J. (1974) The psychology of animal learning. London: Academic Press. [RLM]Google Scholar

Malmo, H. P. & Malmo, R. B. (1977) Movement-related forebrain and midbrain multiple unit activity in rats. Electroencephalography and Clinical Neurophysiology 42:501–09. [RBM]CrossRefGoogle ScholarPubMed

Marshall, J. F. (1978) Comparison of the sensorimotor dysfunctions produced by damage to lateral hypothalamus or superior colliculus in the rat. Experimental Neurology 58:203–17. [PRS taRAW]CrossRefGoogle Scholar

Marshall, J. F., Berrios, N. & Sawyer, S. (1980) Neostriatal dopamine and sensory inattention. Journal of Comparative and Physiological Psychology 94:833–46. [rRAW]CrossRefGoogle ScholarPubMed

Marshall, J. F. & Teitelbaum, P. (1974) Further analysis of sensory inattention following lateral hypothalamic damage in rats. Journal of Comparative and Physiological Psychology 86:375–95. [PRS, taRAW]CrossRefGoogle Scholar

Marshall, J. F., Turner, B. H. & Teitelbaum, P. (1971) Sensory neglect produced by lateral hypothalamic damage. Science 174:523–25. [taRAW]CrossRefGoogle ScholarPubMed

Mason, S. T., Beninger, R. J., Fibiger, H. C. & Phillips, A. G. (1980) Pimozide-induced suppression of responding: Evidence against a block of food reward. Pharmacology, Biochemistry and Behavior 12:917–23. [RJB, WJF, DN, taRAW]CrossRefGoogle Scholar

McGhie, A. (1969) Pathology of attention. Baltimore, Md.: Penguin Books. [PRS]Google Scholar

McKinney, W. T. & Moran, E. C. (1981) Animal models of schizophrenia. American Journal of Psychiatry 138:478–83. [PRS]Google ScholarPubMed

Meehl, P. E. (1962) Schizotaxia, schizotypy, schizophrenia. American Psychologist 17:827–38. [CBN, PRS]CrossRefGoogle Scholar

Mellgren, R. L. & Olson, M. W. (1980) Associative processes controlling the persistence of operant responding: S-S* and R-S*. Bulletin of the Psychonomic Society 16:279–82. [RLM]CrossRefGoogle Scholar

Mellgren, R. L., Seybert, J. A. & Dyck, D. G. (1978) The order of continuous partial and nonreward trials and resistance to extinction. Learning and Motivation 9:359–71. [RLM]CrossRefGoogle Scholar

Meltzer, H. Y. & Stahl, S. M. (1976) The dopamine hypothesis of schizophrenia. Schizophrenia Bulletin 2:19–76. [PRS]CrossRefGoogle ScholarPubMed

Mendelson, J. & Freed, W. J. (1973) Do rats terminate hypothalamic stimulation only in order to turn it on again? Behavioral Biology 8:619–28. [WJF]CrossRefGoogle ScholarPubMed

Miliaressis, E., Bouchard, A. & Jacobowitz, D. M. (1975) Strong positive reward in median raphe: Specific inhibition by para-chlorophenylalanine. Brain Research 98:194–201. [taRAW]CrossRefGoogle ScholarPubMed

Miller, J. D., Sanghera, M. K. & German, D. C. (1981) Mesencephalic dopaminergic unit activity in the behaviorally conditioned rat. Life Sciences. In press. [DCG]CrossRefGoogle ScholarPubMed

Miller, N. E. (1960) Motivational effects of brain stimulation and drugs. Federation Proceedings 19:846–54. [JL]Google ScholarPubMed

Moore, K. E. (1978) Amphetamines: Biochemical and behavioral actions in animals. In: Handbook of psychopharmacology, vol. 2, eds. Iverson, L. L., Iverson, S. D. & Snyder, S. H., pp. 42–98. New York: Plenum Press. [WHL]Google Scholar

Mowrer, O. H. & Jones, H. M. (1945) Habit strength as a function of the pattern of reinforcement. Journal of Experimental Psychology 35:293–311. [RLM]CrossRefGoogle Scholar

Nazzaro, J. M., Seeger, T. F. & Gardner, E. L. (1981) Morphine differentially affects ventral tegmental and substantia nigra brain reward thresholds. Pharmacology, Biochemistry and Behavior 14:325–31. [CBN]CrossRefGoogle ScholarPubMed

Neal, C. D., Collis, M. P. & Imlah, N. W. (1969) A comparative trial ofoxypertine and chlorpromazine in chronic schizophrenia. Current Therapeutic Research 11:367–78. [WJF]Google ScholarPubMed

Neale, J. M. & Oltmanns, T. (1980) Schizophrenia. New York: Wiley. [PRS]Google Scholar

Neill, D. B. & Justice, J. B. Jr. (1981) An hypothesis for a behavioral function of dopaminergic transmission in nucleus accumbens. In: The neurobiology of the nucleus accumbens, ed. Chronister, R. B. & DeFrance, J. F., pp. 343–50. Brunswick: Haer Institute. [DN]Google Scholar

Niemegeers, C. J. E. & Janssen, P. A. J. (1979) A systematic study of the pharmacological activities of dopamine antagonists. Life Sciences 24:2201–16. [taRAW]CrossRefGoogle ScholarPubMed

Panksepp, J. (1981) Hypothalamic integration of behavior: Rewards, punishments, and related psychological processes. In: Handbook of the hypothalamus, behavioral studies of the hypothalamus, vol. 3, part b, ed. Morgane, P. J. and Panksepp, J., pp. 289–431. New York: Marcel Dekker. [JP]Google Scholar

Panksepp, J. (1982) Toward a general psychobiological theory of emotions. Behavioral and Brain Sciences 5. In press. [JP]CrossRefGoogle Scholar

Phillips, A. G. & Broekkamp, C. L. (1980) Inhibition of intravenous cocaine self-administration by rats after microinjection of spiroperidol into the nucleus accumbens. Society for Neuroscience Abstracts 6:105. [taRAW]Google Scholar

Phillips, A. G. & Fibiger, H. C. (1978) The role of dopamine in maintaining self-stimulation of the nucleus accumbens in the rat. Canadian Journal of Psychology 32:58–76. [NWM]CrossRefGoogle Scholar

Phillips, A. G. & Fibiger, H. C. (1979) Decreased resistance to extinction after haloperidol: Implications for the role of dopamine in reinforcement. Pharmacology, Biochemistry and Behavior 10:751–60. [RJB, AE, taRAW]CrossRefGoogle ScholarPubMed

Phillips, A. G. & LePiane, F. G. (1980) Reinforcing effects of morphine microinjection into the ventral tegmental area. Pharmacology Biochemistry and Behavior 12:965–68. [rRAW]CrossRefGoogle ScholarPubMed

Phillipson, O. T. (1979) A golgi study of the ventral tegmental area of Tsai and interfascicular nucleus in the rat. Journal of Comparative Neurology 187:99–116. [DCG]CrossRefGoogle ScholarPubMed

Pickens, R. & Harris, W. C. (1968) Self-administration of d-amphetamine by rats. Psychopharmacologia 12:158–63. [taRAW]CrossRefGoogle ScholarPubMed

Pijnenburg, A. J. J., Honig, W. M. M. & Van Rossum, J. M. (1975) Effects of antagonists upon locomotor stimulation induced by injection of dopamine and noradrenaline into nucleus accumbens of nialamide-pretreated rats. Psychopharmacologia 142:175–80. [WHL]CrossRefGoogle Scholar

Pinel, J. P. J. & Triet, D. (1978) Burying as a defensive response in rats. Journal of Comparative and Physiological Psychology 92:708–12. [RJB]CrossRefGoogle Scholar

Posluns, D. (1962) An analysis of chlorpromazine-induced suppression of the avoidance response. Psychopharmacologia 3:361–73. [RJB]CrossRefGoogle ScholarPubMed

Powell, E. W. & Leman, R. B. (1976) Connections of the nucleus accumbens. Brain Research 105:389–403. [DCG]CrossRefGoogle Scholar

Pribram, K. H. & McGuinness, D. (1975) Arousal, activation, and effort in the control of attention. Psychological Review 82:116–49. [RBM]CrossRefGoogle ScholarPubMed

PriceM. T, C. M. T, C. & Fibiger, H. C. (1975) Discriminated escape learning and response to electric shock after 6-hydroxydopamine lesions of the nigroneostriatal dopaminergic projection. Pharmacology, Biochemistry and Behavior 3:285–90. [RJB]CrossRefGoogle ScholarPubMed

Prowse, J., Noreika, L., Gerhardt, S. & Liebman, J. (1981) Selective attenuation of intracranial self-stimulation by the beta-2 agonist, salbutamol. Federation Proceedings 40:293. [JL]Google Scholar

Rachlin, H., Green, L., Kagel, J. H. and Battalio, R. C. (1976) Economic demand theory and psychological studies of choice. In: The psychology of learning and motivation, vol. 10, ed. Bower, G. H., pp. 129–54. New York: Academic Press. [HMS]CrossRefGoogle Scholar

Rado, S. (1956) Dynamics and classification of disordered behavior. In: Psychoanalysis of behavior: The collected papers of Sandor Rado, vol. 1, 1922–1956, pp. 268–85. New York: Grune & Stratton. [CBN]Google Scholar

Rado, S. (1962) Theory and therapy: The theory of schizotypal organization and its application to the treatment of decompensated schizotypal behavior. In: Psychoanalysis of behavior: The collected papers of Sandor Rado, vol. 2, 1956–1961, pp. 127–40. New York: Grune & Stratton. [CBN]Google Scholar

Rado, S. (1969) Adaptational psychodynamics: Motivation and control. New York: Science House. [CBN]Google Scholar

Ranje, C. & Ungerstedt, U. (1977a) Lack of acquisition in dopamine denervated animals in an underwater Y-maze. Brain Research 134:95–111. [RJB, taRAW]CrossRefGoogle Scholar

Ranje, C. & Ungerstedt, U. (1977b) Discriminative and motor performance in rats after interference with dopamine neurotransmission with spiroperidol. European Journal of Pharmacology 43:39–46. [HA, RJB, taRAW]CrossRefGoogle ScholarPubMed

Rech, R. H. & Borys, H. K. (1965) Comparison of CNS depressants using a battery of behavioral tests. Pharmacologist 7:171. [RHR]Google Scholar

Rech, R. H. & Pirch, J. H. (1971) Some fundamentals of pharmacology and psychology. In: An introduction to psychopharmacology, ed. Rech, R. H. & Moore, K. E., pp. 32–34. New York: Raven Press. [RHR]Google Scholar

Rech, R. H. & Stolk, J. M. (1970) Amphetamine-drug interactions that relate brain catecholamines to behavior. In: International symposium on amphetamines and related compounds, ed. Costa, E. & Garattini, S., pp. 385–94. New York: Raven Press. [RHR]Google Scholar

Reisine, T. D. (1981) Adaptative changes in catecholamine receptors in the central nervous system. Neuroscience 6:1471–1581. [PS]CrossRefGoogle ScholarPubMed

Risner, M. J. E. & Jones, B. E. (1976) Role of noradrenergic and dopaminergic processes in amphetamine self-administration. Pharmacology, Biochemistry and Behavior 5:477–82. [taRAW]CrossRefGoogle ScholarPubMed

Risner, M. J. E. & Jones, B. E. (1980) Intravenous self-administration of cocaine and norcocaine by dogs. Psychopharmacology 71:83–89. [WJF, taRAW]CrossRefGoogle ScholarPubMed

Roberts, D. S. C., Corcoran, M. E. & Fibiger, H. C. (1977) On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacology, Biochemistry and Behavior 6:615–20. [WHL, taRAW]CrossRefGoogle ScholarPubMed

Roberts, D. C. S., Koob, G. F., Klonoff, P. & Fibiger, H. C. (1980) Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacology, Biochemistry & Behavior 12:781–87. [DCG, CBN, taRAW]CrossRefGoogle ScholarPubMed

Robinson, P., Daley, M. & Wolff, P. C. (1967). Apomorphine induced reinforcement. Psychonomic Science 7:117–18. [RJK]CrossRefGoogle Scholar

Roll, S. K. (1970) Intracranial self-stimulation and wakefulness: Effect of manipulating ambient brain catecholamines. Science 168:1370–72. [taRAW]CrossRefGoogle ScholarPubMed

Rolls, E. T., Kelly, P. H. & Shaw, S. G. (1974) Noradrenaline, dopamine, and brain-stimulation reward. Pharmacology, Biochemistry and Behavior 2:735–40. [taRAW]CrossRefGoogle ScholarPubMed

Rolls, E. T., Rolls, B. J., Kelly, P. H., Shaw, S. G., Wood, R. J. & Dale, R. (1974) The relative attenuation of self-stimulation, eating and drinking produced by dopamine-receptor blockade. Psychopharmacologia 38:219–30. [taRAW]CrossRefGoogle ScholarPubMed

Rosenblatt, W. H., Hutchins, K. & Sinnamon, H. M. (1979) Pimozide's effects on ICSS depend on the interaction of reward and effort. Society for Neuroscience Abstracts 5:350. [HMS]Google Scholar

Royall, D. R. & Klemm, W. R. (1981) Dopaminergic mediation of reward: Evidence gained using a natural reinforcer in a behavioral contrast paradigm. Neuroscience Letter 21:223–29. [CBN, WRK]CrossRefGoogle Scholar

Ruffieux, A. & Schultz, W. (1980) Dopaminergic activation of reticulata neurones in the substantia nigra. Nature 285:240–42. [DCG]CrossRefGoogle ScholarPubMed

Sahakian, B. J. & Robbins, T. W. (1977) Isolation-rearing enhances tail pinch behavior in rats. Physiology and Behavior 18:53–58. [GFK]CrossRefGoogle Scholar

Sanghera, M. K., German, D. C. & Kiser, R. S. (1979) Dopamine neuronal activity during operant behavior. Federation Proceedings 38:256. [DCG]Google Scholar

Schaefer, G. P. & Michael, R. P. (1979) Acute effects of neuroleptics on brain self-stimulation thresholds in rats. Psychopharmacology 67:9–15. [AE, taRAW]CrossRefGoogle Scholar

Scull, J., Davies, K. & Amsel, A. (1970) Behavioural contrast and frustration effect in multiple and mixed fixed interval schedules in the rat. Journal of Comparative and Physiological Psychology 71:478–83. [GFK]CrossRefGoogle Scholar

Schwartzbaum, J. S. (1975) Interrelationship among multiunit activity of the midbrain reticular formation and lateral geniculate nucleus, thalamocortical arousal, and behavior in rats. Journal of Comparative and Physiological Psychology 89:131–57. [RBM]CrossRefGoogle Scholar

Seeman, P. (1980) Dopamine receptors. Pharmacological Reviews 32:229–313. [RJK, taRAW]Google Scholar

Sheffield, V. F. (1950) Resistance to extinction as a function of the distribution of extinction trials. Journal of Experimental Psychology 40:305–13. [GFK]CrossRefGoogle Scholar

Siegel, J. M. (1979) Behavioral functions of the reticular formation. Brain Research Reviews 1:69–105. [RBM]CrossRefGoogle Scholar

Simon, H., LeMoal, M. & Cardo, B. (1975) Self-stimulation in the dorsal pontine tegmentum in the rat. Behavioral Biology 13:339–47. [rRAW]CrossRefGoogle Scholar

Simon, H., Le Moal, M. & Koob, G. F. (1981) Effects of 6-OHDA lesions to the frontal cortex, nucleus accumbens or corpus striatum on amphetamine-induced behavior and acquisition of the conditioned avoidance response. Neuroscience Abstracts 7:155. [GFK]Google Scholar

Simon, H., Stinus, L., Tassin, J. P., Lavielle, S., Blanc, G., Thierry, A. M., Glowinski, J. & LeMoal, M. (1979) Is the dopaminergic mesocorticolimbic system necessary for intracranial self-stimulation? Behavioral and Neural Biology 27:125–15. [GFK, rRAW]CrossRefGoogle ScholarPubMed

Snyder, S. H. (1981) Dopamine receptors, neuroleptics and schizophrenia. American Journal of Psychiatry 138:460–64. [CBN]Google Scholar

Solomon, P. R., Crider, A., Winkelman, J. W., Turi, A., Kamer, R. M. & Kaplan, L. J. (1981) Disrupted latent inhibition in the rat with chronic amphetamine or haloperidol-induced supersensitivity: Relationship to schizophrenic attention disorder. Biological Psychiatry 16:519–37. [PRS]Google ScholarPubMed

Spear, N. E., Hill, W. F. & O'Sullivan, D. J. (1965) Acquisition and extinction after initial trials without reward. Journal of Experimental Psychology 69:25–29. [RLM]CrossRefGoogle ScholarPubMed

Spohn, H. E., Lacoursiere, R. B., Thompson, K. & Coyne, L. (1977) Phenothiazine effects on psychological and psychophysiological dysfunction in chronic schizophrenics. Archives of General Psychiatry 34:633–44. [WJF, PRS]CrossRefGoogle ScholarPubMed

Staddon, J. E. R. (1979) Operant behavior as adaptation to constraint. Journal of Experimental Psychology: General 108:48–67. [HMS]CrossRefGoogle Scholar

Stapleton, J. M., Merriman, V. J., Coogle, C. L., Gelbard, S. D. & Reid, L. D. (1979) Naloxone reduces pressing for intracranial stimulation of sites in the periacqueductal gray area, accumbens nucleus, substantia nigra, and lateral hypothalamus. Physiological Psychology 7:427–36. [taRAW]CrossRefGoogle Scholar

Staton, D. M. & Solomon, P. R. (1980) Microinjections of d-amphetamine in the nucleus accumbens disrupt the rat's ability to learn to ignore an irrelevant stimulus. Society for Neuroscience Abstracts 6:169. [PRS]Google Scholar

Stein, L. (1980) The chemistry of reward. In Biology of reinforcement: facets of brain stimulation reward ed. Routtenberg, A., pp. 109–30. New York: Academic Press. [rRAW]Google Scholar

Steiner, J. E. (1973) The human gustofacial response. In: Fourth symposium on oral sensation and perception, ed. Bosma, J. F., pp. 254–78. Bethesda, Md.: U. S. Dept. of Health, Education, and Welfare. [LDK]Google Scholar

Stricker, E. M. & Zigmond, M. J. (1976) Recovery of function following damage to central catecholamine-containing neurons: A neurochemical model for the lateral hypothalamic syndrome. In: Progress in psychobiology and physiological psychology, vol. 6, ed. Sprague, J. M. and Epstein, A. N.. New York: Academic Press. [RJK, taRAW]Google Scholar

Szostak, C. & Tombaugh, T. N. (1981) The effects of pimozide on the performance of conditional discrimination tasks as a function of task complexity. Paper presented to the Canadian College of Psychopharmacology, Toronto. [taRAW]Google Scholar

Teitelbaum, P., Schallert, T., DeRyck, M., Whishaw, I. Q. & Colani, I. (1980) Motor subsystems in motivated behavior. In: Neural mechanisms of goal-directed behavior and learning, ed. Thompson, R. F., Hicks, L. H. & Shvyrkov, V. B., pp. 127–44. New York: Academic Press. [RJB]CrossRefGoogle Scholar

Thompson, T., Heistad, G. J. & Palmero, D. S. (1963) Effect of amount of training on rate and duration of responding during extinction. Journal of Experimental Psychology – Animal Behavior 6:155–61. [GFK]Google ScholarPubMed

Tombaugh, T. N. (1981) Effects of pimozide on nondiscriminated and discriminated performance in the pigeon. Psychopharmacology 73:137–46. [TNT]CrossRefGoogle Scholar

Tombaugh, T. N., Anisman, H. & Tombaugh, J. (1980) Extinction and dopamine receptor blockade after intermittent reinforcement training: Failure to observe functional equivalence. Psychopharmacology 70:19–28. [RJB, AE, WJF, taRAW]CrossRefGoogle ScholarPubMed

Tombaugh, T. N. & Mills, P. (1981) The effects of pimozide on the acquisition of a simultaneous discrimination. Paper presented at Canadian Psychological Association meeting, Toronto. [TNT]Google Scholar

Tombaugh, T. N., Ritch, M. A. & Shepherd, D. T. (1980) Effects of pimozide on accuracy of performance and distribution of correct responding on a simultaneous discrimination task in the rat. Pharmacology, Biochemistry and Behavior 13:859–62. [TNT]CrossRefGoogle ScholarPubMed

Tombaugh, T. N., Tombaugh, J. & Anisman, H. (1979) Effects of dopamine receptor blockade on alimentary behaviors: Home cage food consumption, magazine training, operant acquisition, and performance. Psychopharmacology 66:219–25. [HA, RJB, taRAW]CrossRefGoogle ScholarPubMed

Trowill, J. A., Panksepp, J. & Gandelman, R. (1969) An incentive model of rewarding brain stimulation. Psychological Review 76:264–81. [JP]CrossRefGoogle ScholarPubMed

Uguru-Okorie, D. C. & Arbuthnott, G. W. (1981) Altered paw preference after unilateral 6-hydroxy-dopamine injections into lateral hypothalamus. Neuropsychology 19:463–67. [GWA]CrossRefGoogle ScholarPubMed

Ungerstedt, U. (1979) Central dopamine mechanisms and unconditioned behavior. In: The neurobiology of dopamine, ed. Horn, A. S., Korf, J. & Westerink, B. H. C., pp. 577–96. New York: Academic Press. [RJB]Google Scholar

Valenstein, E. S. (1964) Problems of measurement and interpretation with reinforcing brain stimulation. Psychological Review 71:415–37. [taRAW]CrossRefGoogle ScholarPubMed

Valzelli, L. & Garattini, S. (1970) Pharmacology of phenothiazines. In: Principles of psychopharmacology ed. Clark, W. G. & delGuidice, J.. pp. 255–67. New York: Academic Press. [taRAW]Google Scholar

van der Kooy, D., LePiane, F. G. & Phillips, A. G. (1977) Apparent independence of opiate reinforcement and electrical self-stimulation systems in rat brain. Life Sciences 20:981–86. [WRK]CrossRefGoogle ScholarPubMed

Vanderwolf, C. H. & Robinson, T. E. (1981) Reticulo-cortical activity and behavior: A critique of the arousal theory and a new synthesis. The Behavioral and Brain Sciences 4:459–514. [RBM]CrossRefGoogle Scholar

Wauquier, A. (1976) The influence of psychoactive drugs on brain self-stimulation in rats: A review. In: Brain stimulation reward, ed. Wauquier, A. & Rolls, E. T., pp. 123–70. New York: Elsevier. [taRAW]Google Scholar

Wauquier, A. (1976) (1979) Neuroleptics and brain self-stimulation behavior. International Review of Neurobiology 21:335–403. JL, taRAW]CrossRefGoogle Scholar

Wauquier, A. & Niemegeers, C. J. E. (1979) A comparison between lick or lever-pressing contingent reward and the effects of neuroleptics thereon. Archives Internationales de Pharmacodynamie et de Therapie 239:230–40. [JP, taRAW]Google ScholarPubMed

White, N. (1976) Strength-duration analysis of the organization of reinforcement pathways in the medial forebrain bundle of rats. Brain Research 110:575–91. [taRAW]CrossRefGoogle ScholarPubMed

White, N., Brown, Z. & Yachnin, M. (1978) Effects of catecholamine manipulations on three different self-stimulation behaviors. Pharmacology, Biochemistry and Behavior 9:603–08. [JP, taRAW]CrossRefGoogle Scholar

Wilson, M. C., Hitomi, M. & Schuster, C. R. (1969) Further studies of the self-administration of psychomotor stimulation in the rhesus monkey. Minutes of meeting of the committee on problems of drug dependence, NAS-NRC, Palo Alto, Calif. [GFK]Google Scholar

Wilson, M. C. & Schuster, C. R. (1972) The effects of chlorpromazine on psychomotor stimulant self-administration in the rhesus monkey. Psychopharmacologia 26:115–26. [GFK, taRAW]CrossRefGoogle Scholar

Wise, R. A. (1980) Action of drugs of abuse on brain reward systems. Pharmacology, Biochemistry and Behavior 13:213–23. [CBN, taRAW]CrossRefGoogle ScholarPubMed

Wise, R. A. (1974) Lateral hypothalamic electrical stimulation: Does it make animals hungry? Brain Research 67:187–209. [rRAW]CrossRefGoogle ScholarPubMed

Wise, R. A. & Schwartz, H. V. (1981) Pimozide attentuates acquisition of lever-pressing for food in rats. Pharmacology, Biochemistry and Behavior. In press. [RJB, taRAW]CrossRefGoogle Scholar

Wise, R. A., Spindler, J., deWit, H. & Gerber, G. J. (1978) Neuroleptic-induced “anhedonia” in rats: Pimozide blocks reward quality of food. Science 201:262–64. [taRAW]CrossRefGoogle ScholarPubMed

Wise, R. A., Spindler, J. & Legault, L. (1978) Major attenuation of food reward with performance-sparing doses of pimozide in the rat. Canadian Journal of Psychology 32:77–85. [NWM, taRAW]CrossRefGoogle ScholarPubMed

Wise, R. A., Yokel, R. A. & deWit, H. (1976) Both positive reinforcement and conditioned aversion from amphetamine and from apomorphine in rats. Science 191:1273–74. [WHL, taRAW]CrossRefGoogle ScholarPubMed

Wuerthele, S. M., Olson, L., Freed, W. J., Morihisa, J., Spoor, L., Wyatt, R. J. & Hoffer, B. J. (1980) Electrophysiological characteristic of substantia nigra brain grafts in the lateral ventricle. Neuroscience Abstracts 6:327. [DCG]Google Scholar

Yokel, R. A. & Wise, R. A. (1975) Increased lever pressing for amphetamine after pimozide: Implications for a dopamine theory of reward. Science 187:547–49. [AE, taRAW]CrossRefGoogle ScholarPubMed

Yokel, R. A. & Wise, R. A. (1976) Attenuation of intravenous amphetamine reinforcement by central dopamine blockade in rats. Psychopharmacology 48:311–18. [WJF, WHL, taRAW]CrossRefGoogle ScholarPubMed

Yokel, R. A. & Wise, R. A. (1978) Amphetamine-type reinforcement by dopamine agonists in the rat. Psychopharmacology 58:289–96. [taRAW]CrossRefGoogle ScholarPubMed

Zarevics, P. & Setler, P. E. (1981) Effects of GABAergic drugs on brain stimulation reward as assessed by a “threshold” method. Brain Research 215:201–09. [PS]CrossRefGoogle Scholar

Zarevics, P., Weidley, E. & Setler, P. E. (1977) Blockade of intracranial self-stimulation by antipsychotic drugs: Failure to correlate with central alpha-noradrenergic blockade. Psychopharmacology 53:283–88. [taRAW]CrossRefGoogle ScholarPubMed